#NEXUS
[!This data set was downloaded from TreeBASE, a relational database of phylogenetic knowledge. TreeBASE has been supported by the NSF, Harvard University, Yale University, SDSC and UC Davis. Please do not remove this acknowledgment from the Nexus file.


Generated on September 19, 2025; 0:31 GMT

TreeBASE (cc) 1994-2008

Study reference:
Casewell N.R., Wagstaff S.C., Harrison R.A., & Wuster W. 2010. Gene tree parsimony
of multi-locus snake venom protein families reveals species tree conflict as a
result of multiple parallel gene loss. Molecular Biology and Evolution, .

TreeBASE Study URI:  http://purl.org/phylo/treebase/phylows/study/TB2:S10791]

BEGIN TAXA;
        TITLE  Echis;
        DIMENSIONS NTAX=27;
        TAXLABELS
            Echis_carinatus_sochureki_07B03_ECS00244
            Echis_carinatus_sochureki_09A02_ECS00105
            Echis_carinatus_sochureki_11A11_ECS00134
            Echis_carinatus_sochureki_11F09_ECS00186
            Echis_coloratus_01C11_ECO00042
            Echis_coloratus_01G12_ECO00013
            Echis_coloratus_03A12_ECO00135
            Echis_coloratus_03G08_ECO00112
            Echis_coloratus_04E01_ECO00164
            Echis_coloratus_04E05_ECO00161
            Echis_coloratus_05D01_ECO00206
            Echis_coloratus_05H12_ECO00182
            Echis_coloratus_08A11_ECO00182
            Echis_coloratus_11A06_ECO00285
            Echis_coloratus_13E06_ECO00285
            Echis_coloratus_13F10_ECO00419
            Echis_ocellatus_02E07_EOC00185
            Echis_ocellatus_02F07_EOC00181
            Echis_ocellatus_03E02_EOC00049
            Echis_ocellatus_05B06_EOC00049
            Echis_ocellatus_06E11_EOC00049
            Echis_ocellatus_10B04_EOC00315
            Echis_pyramidum_leakeyi_03A08_EPL00141
            Echis_pyramidum_leakeyi_03H09_EPL00098
            Echis_pyramidum_leakeyi_13A12_EPL00502
            Echis_pyramidum_leakeyi_13B07_EPL00435
            Homo_sapiens_13897994
            ;
END;

BEGIN CHARACTERS;
[! TreeBASE Matrix URI: http://purl.org/phylo/treebase/phylows/matrix/TB2:M6402]

	TITLE Echis_serine_protease_amino_acid_alignment;
	LINK TAXA = Echis;
	DIMENSIONS NCHAR=260;
	FORMAT DATATYPE=Protein SYMBOLS= "A C D E F G H I K L M N P Q R S T V W Y" MISSING=? GAP= -;

MATRIX
[                                                    10        20        30        40        50        60        70        80        90        100       110       120       130       140       150       160       170       180       190       200       210       220       230       240       250       260]
[                                                     .         .         .         .         .         .         .         .         .         .         .         .         .         .         .         .         .         .         .         .         .         .         .         .         .         .]
Echis_carinatus_sochureki_07B03_ECS00244     MVLIRVLANLLVLQLSYAQKSSELVIGGAECNINEHRFLAFVYNSSG--FACGGTLINEEWVLTAAHCDRENIRIYFGLHNLKQPNKDRKRRVAEKKFFCQR--NHTMWDNDIMLIKLDKPVTSSTHIAPISLPSSPPSVGSVCRIMGWGSITSPNLTRPDVPHCAKIKILKHKVCQRAYKRNLANSKILCAGIRKGGKDTCQGDSGGPLICNGQFQGVVAGGATPCAQPRMPGIY????????????????????????
Echis_carinatus_sochureki_09A02_ECS00105     MVLIRVLANLLVLQLSYAQKSSELVTGGAECDINEHRFLVALYTASSSTFHCAGTLINHEWVLTAVHCDRKNIRIKLGMHSKNMPNEDEQIRVPKKKVFCHNSKFPNGMDKDIMLIRLRRPVNNSTHIAPVSLPSSPSSPRSRCRIMGWGKISSAEDTDSIVPHCANIFVVKHSWCEAIYPWVPADSRTLCAGILQGGKDTCHGDSGGPLICNGQIQGIVSGGSEPCGQRLKPAV?????????????????????????
Echis_carinatus_sochureki_11A11_ECS00134     MVLIRVLANLLVLQLCYAQKSSELVIGGAECNINEHRSLALVFNSSG--FICGGTLINQEWVLSAAHCDVENMQIYLGLHNFSPPNKEHKERVAKEKFFCLPSRNYTLWDKDIMLIKLNRPVKNSAHIAPLHLPSNPPRLGSVCRIMGWGSIISPNEKMSYVPHCANINILRYSLCQVIYGGLPDKSRTLCAGILGTRIGSCKGDSGGPLICDGQIQGIVSWVSKPCAHHGAPGM?????????????????????????
Echis_carinatus_sochureki_11F09_ECS00186     MVLIRMLANLLVLQLSYAQKSSELVTGGDECNINEHPFLVALHTARSKRFHCTGTLINEQWVLTAARCNRKNIRIKLGVHNKNVRNENEEMRVPAEKVFCVSSKTYTRWDKDIMLIKMKRPVNNSTHIAPLSLPSNPASVGSVCRIMGWGTITTTKVTYPDVPHCANIKIFDYSVCRGAYRKLPEKSRTLCAGVLEGGIDSCKADTGGPLICNGQFQGIASWGGQPCAQPLKPALYT???????????????????????
Echis_coloratus_01C11_ECO00042               MVLIRVLANLLVLQLSYAQKSSELIIGGAECNINDHRFLVALYNYRTRAFLCGGTLINQEWVLSAAHCNRKSLQIKIGMHSKTAPNDDLQTRVPKETYFCLPNKNYTMWDKDIMLIKLNRPVNNSTHIAPISLPSNRPSLGSVCRIMGWGSIIPTNETYPDVPHCTNINLLHYSVCRAAYPWLPVNSRTFCAGVLQGGKDTCKGDSGGPLICNGQFQGILSWGWTPCAQLLEPALYTKVFDYSDWIQSIIAGNTTASCPP
Echis_coloratus_01G12_ECO00013               MVLIRVLANLLVLQLSYAQKSSELVIGGSPCNITEHRSLVVMFNSSA--FLCAGTLINQEWVLTAAHCDSDNFQMLLGVHSKKVLNEDEETREPKEKVYCVSHEKNTDWAKDIMLIKLNKPVKSSTHIAPLSLPSSPPSVGSVCRIMGWGTISSTELTYPDVPHCANIKILNHKVCQAAHPKLLAESRTLCAGILEGGKDTCQGDSGGPLICDGQIQGIVSWGGHPCGEHLSPGVY????????????????????????
Echis_coloratus_03A12_ECO00135               MVLIRVLANLLVLHFSYAQKSSELVIGGAECNINGHRSLAVLHNSSG--LLCSGTLINEEWVLSAAHCDMENMQIYLGYHNFSVPNDDEEIRVPVEKYFCLPRRNYIVWGKDIMLIKLNRSVNISTHIAPLSLPSSPPSLDSVCRIMGWGAITSPNETYSNVPHCANINILHSSVCRAAYGRLPGLSRTLCAGILRGGIDSCKGDSGGPLICNGQFQGIVSWGDHPCGQRRKPGIYTKVFDYTDWVQSIIAGNTAVTCPP
Echis_coloratus_03G08_ECO00112               MVLIRVLANLLVLQLSYAQKSSELIIGGAECDINEHRSLALVYHGN---YQCGGTLINQEWVLTAAHCDGKTMKIHFGVHSKKKQNKDKQIRVPKEKFFCLPSRNYTMWDKDIMLIKLNKPVKNSTHIAPLSLPSNPPRLGSVCRIMGWGTISTTKVILPDVPHCVNINLLNYSECQAVHPELPEKGRTLCAGVLEGGKDTCHGDSGGPLICNGQIQGISSWGGDPCAQPHEPAL?????????????????????????
Echis_coloratus_04E01_ECO00164               MVLIRVLANLLVLQLSYAQKSSELVIGGAECNINEHRSLALIYNSTSMWFHCSGTLLNQEWVLTAAHCEMENMQIYLGVHNKTKRNKDQQKRFPKKKYFCLKSKNFTLWDKDIMLIKLNRPVKSSTHIEPFSLPSSPPSVGSVCRIMGWGAINSPNETFPDVPHCANIKLYNYSVCREAYGGLPEKSRTLCAGVLEGGIDTCMADSGGPLICNGQFQGIVSWGRHPCAQPLLPAFYT???????????????????????
Echis_coloratus_04E05_ECO00161               MVLIRVLANLLVLQLSYAQKSSELVIGGAECNINEHRSLALIYNSTSMWFHCSGTLLNQEWVLTAAHCEMENMQIYLGVHNKTKRNKDQQKRFPKKKYFCLKSKNFTLWDKDIMLIKLNRPVKSSMHIEPFSLPSSPPSVGSVCRIMGWGAINSPNETFPDVPHCANIKLYNYSVCREAYGGLPEKSRTLCAGVLEGGIDTCMADSGGPLICNGQFQGIVSWGRHPCAQPLLPAFY????????????????????????
Echis_coloratus_05D01_ECO00206               MVLIRVLANLLVLQLSYAQKSSELVTGGAECDINEHPFLVALYTASSSTFHCAGTLINQEWVLTAVHCDRKKIRIKLGMHSKNMPNEDEQIRVPKKKVFCHNSKFPNGMDKDIMLIKLRRPVNNSAHIAPISLPSSPSSPRSRCRIMGWGKISSAEDTDSLVPHCANIFIVKHSWCEAIYPWVPADSRTLCAGILQGGKDTCHGDSGGPLICNGQIQGIVSGGSEPCGQRLKPAVYTKVFDYTDWIQSIIAGNTTVTCPP
Echis_coloratus_05H12_ECO00182               MVLIRVLANLLVLQLSYAQKSSELVIGGAECDINEHRSLVLVYNASG--FLCGGTLINREWVLSAAHCYMKNMRIYLGLHNFSLPNNDQQRRGARETYFCLPSRNYTKWDKDIMLIKLNRPVNYSTHIAPLRLPSNPPHLGSVCHIMGWGAITSPNETHPDVPHCANINILRYSICRAAYGGLPAQSRTLCAGILGRRIGSCKGDSGGPLICNGQIQGIVSWGAKVCARPRAPGLYTKVFD?TDWIQSI?AGNTTA??PP
Echis_coloratus_08A11_ECO00182               MVLIRVLANLLVLQLSYAQKSSELVIGGAECDINEHRSLVLVYNASG--FFCGGTLINREWVLSAAHCYMKNMRIYLGLHNFSLPNNDQQRRGARETYFCLPSRNYTKWDKDIMLIKLNRPVNYSTHIAPLHLPSNPPHLGSVCHIMGWGAITSPNETHPDVPHCANINILRYSICRAAYGGLPAQSRTLCAGILGRRIGSCKGDSGGPLICNGQIQGIVSWGAKVCARPRAPGLYTK??????????????????????
Echis_coloratus_11A06_ECO00285               MVLIRVLANLLVLQLSYAQRSSELVTGGAECDINEHPFLVALHTARSKRFHCTGTLIDNQWVLTAARCDRKNIRIKVGVHNKNKRNKDEMMRVPAEKFFCASSKTYTRWDKDIMLIRLKRPVNGSTHIAPLSLPSNPASVDSECRIMGWGTITTTKVTYPDVPHCANIKIFDYSVCREAYRKLPEKSRTLCAGILERSIDSCKADTGGPLICNGQFQGIASWGGKPCAQPLKPALYTNVFDYNDWIKSIIAGNTDATCPP
Echis_coloratus_13E06_ECO00285               MVLIRVLANLLVLQLSYAQRSSELVTGGAECDINEHPFLVALHTARSKRFHCTGTLIDNQWVLTAARCDRKNIRIKVGVHNKNKRNKDEMMRVPAEKFFCASSKTYTRWDKDIMLIRLKRPVNGSTHIAPLSLPSNPASVDSECRIMGWGTITTTKVTYPDVPHCANIKIFDYSVCREAYRKLPEKSRTLCAGILEGGIDSCKADTGGPLICNGQFQGIASWGGKPCAQPLKPALYTNVFDYNDWIKSIIAGNTDATCPP
Echis_coloratus_13F10_ECO00419               MVLIIVLANLLVLQLSYAQKSSELVIGGAECNINEHRSLALVFNSSG--FICGGTLINHEWVLSAAHCDVENMQIYLGLHNFSPPNKEHKKRVAKEKFFCLSSKSYTLWDKDIMLIKLNKPVKNSAHIEPLSLPSNPPRLHSVCRIMGWGSITSPNEKMSYVPHCANINILRYSVCQAIYGGLPDKSRTLCAGILGRRIGSCKGDSGGPLICDGQIQGIVSWVSKPCAHHGAPGMYTKVFDYTDWMQSIIAGSTTATCPP
Echis_ocellatus_02E07_EOC00185               MVLIRSLPHRVILRFCYSPNSYQLFSERAESDINELPFLVSLLTARSKRFHCPGTLIGKQWVLTAARCIKKNIRVKIGMHNQNERTDDEMMTVAAEKFFCASSKTYTIWDKDIMLIKLKRPVNNRTHIAPLSLPSNPASVGSECRIMGWGTTTTTKVTYPDVPHCANIKIFNYSVCREAYRKLPEKSIILCASI??????????????????????????????????????????????????????????????????
Echis_ocellatus_02F07_EOC00181               MVLIRVLANLLVLQLSYAQKSSELVAGGAECDKNEHPFLVALHTARSKRFHCTGTLIGKQWVLTAARCNKKNIRVKIGMHNKNERTEDEMMRVAAEKFFCASSKTYTRWDKDIMLIKLKRPVNNRTHIAPLSLPSNPASVGSECRIMGWGTTTTTKVTYPDVPHCANIKIFDYSVCREAYRKLPEKSRILCAGIL?GGIDSCKADTGGPLICNGEFQGIASWGGQPCAQPLKPALYTNVFDYSDW???????????????
Echis_ocellatus_03E02_EOC00049               MVLIRVLANLLVLQLSYAQMSSELVVGGGECNRNRHRSLALLYNSSG--TLCGGTLIHEEWVLSAAHCDMENMKIYLGLHNLSLPNKDQQKREPRETHFCLPSRNYTLWDKDIMLIKLNRPVKSSPHIAPISLPSNPPRLRSVCHIMGWGAITSPNETYPDVPHCANINILRYSVCRAAFGRLPAQSRTLCAGILRGGIDTCLGDSGGPLICNGQIQGIVSWGAEVCAKPHAPGLYTKVSDYTDWIQSIIAGNTT?????
Echis_ocellatus_05B06_EOC00049               MVLIRVLANLLVLQLSYAQMSSELVVGGGECNRNRHRSLALLYNSSG--TLCGGTLIHEEWVLSAAHCDMENMKIYLGLHNLSLPNKDQQKREPRETHFCLPSRNYTLWDKDIMLIKLNRPVNNSPHIAPISLPSNPPRLRSVCHIMGWGAITSPNETYPDVPHCANINILRYSVCRAAFGRLPAQSRTLCAGILRGGIDTCLGDSGGPLICNGQIQGIVSWGAEVCAKPHAPGLYTKVSDYTDWIQSIIAGNTTATCPP
Echis_ocellatus_06E11_EOC00049               MVLIRVLANLLVLQLSYAQMSSELVVGGGECNRNRHRSLALLYNSSG--TLCGGTLIHEEWVLSAAHCDMENMKIYLGLHNLSLPNKDQQKREPRETHFCLPSRNYTLWDKDIMLIKLNRPVKSSPHIAPISLPSNPPRLRSVCHIMGWGAITSPNETYPDVPHCANINILRYSVCRAAFGRLPA?SRTLCAGILRGGIDTCLGDSGGPLICNGTIQGIVSWG?????????????????????????????????????
Echis_ocellatus_10B04_EOC00315               MVLIRVLANLLVLQLSYAQKSSELVIGGAECDINEHRSLILVYNASG--YYCSGTLIHEEWVLTAVHCYVENMRIHLGMHNFSQRNEDEQRREASETYFCLPDRNYTRWDKDIMLIKLDRPVNNSPHIAPLSLPSNPPSVGSHCRIMGWGAITSPNKTFPRVPHCANIEIIDYSVCRAAFGRLPAQSRTLCAGIL?????????????????????????????????????????????????????????????????
Echis_pyramidum_leakeyi_03A08_EPL00141       MVLIRVLANLLVLQLSYAQKSSELIIGGAECNINEHRSLILVYNASG--YYCSGTLINQEWVLTAVHCYVENMRIHLGVHNLRLRNKEEQRREASETYFCLPSRNYTRWDKDIMLIKLDRPVNNSTHIAPLSLPSNPPSVGSHCRIMGWGAITSPNVTFPKVPHCANIEIIDYSVCRAAHGGLPAQSRTLCAGILQGGIGSCLGDSGGPLICDGQFQGIVAWGGDTCALPREPVMYTKVFDYTEWIQSIIAGNTAATCPP
Echis_pyramidum_leakeyi_03H09_EPL00098       MVLIRVVANLLVLQLSYAQKSSELVIGGAECDINEHRSLALIYNSTSMWFHCSGTLLNEEWVLTAAHCEMENMQIYLGVHNKTKRNKEQQKRFPKKKYFCLKSKNFTLWDKDIMLIKLNRPVKSSTHIEPFSLPSSPPSVGSVCRIMGWGAINSPNETFPEVPHCANIKLYNYSVCREAYGGLPEKSRTLCAGVLEGGIDTCMADSGGPLICNGQFQGIVAWGRHPCAQPLLPAFY????????????????????????
Echis_pyramidum_leakeyi_13A12_EPL00502       ????????????????????????????AECDINEHRSLILVYNASG--YYCSGTLINQEWVLTAVHCYVENMRIHLGVHNLRLRNKEEQRREASETYFCLPSRNYTRWDKDIMLIKLDRPVNNSTHIAPLSLPSNPPSVGSHCRIMGWGAITSPNVTFPKVPHCANIEIIDYSVCRAAHGGLPAQSRTLCAGILQGGIGSCLGDSGGPLICDGQFQGIVAWGGDTCALPREPVMYTKVFDYTEWIQSIIAGNTAATCPP
Echis_pyramidum_leakeyi_13B07_EPL00435       MVLIRVLANLLVLQLSYAQKSSELVIGGAECDINEHRSLALVFNSSG--FICGGTLINHEWVLSAAHCDVENMQIYLGLHNFSPANKEHKKRVAKKKFFCLSSKSYTLWDKDIMLIKLNKPVRNSAHIEPLSLPSNPPRLHSVCRIMGWGSITSPNEKMSYVPHCANINILRYSVCQAIYGGLPDKSRTLCAGILGRRIGSCKGDSGGPLICDGQIQGIVSWVSKPCAHHGAPGM?????????????????????????
Homo_sapiens_13897994                        MFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQWVITAAHCGRPILQVALGKHNLR-RWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPG-MVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWIEETMRDK???????
;
END;