#NEXUS
[!This data set was downloaded from TreeBASE, a relational database of phylogenetic knowledge. TreeBASE has been supported by the NSF, Harvard University, Yale University, SDSC and UC Davis. Please do not remove this acknowledgment from the Nexus file.


Generated on September 19, 2025; 0:33 GMT

TreeBASE (cc) 1994-2008

Study reference:
Belahbib H., Renard E., Santini S., Jourda C., Clavery J., Borchiellini C., & Le
bivic A. 2018. New Genomic Data and Analyses Challenge the Traditional Vision of
Epithelium Evolution in Sponges and Ctenophores. BMC Genomics, .

TreeBASE Study URI:  http://purl.org/phylo/treebase/phylows/study/TB2:S22408]

BEGIN TAXA;
        TITLE  Taxa;
        DIMENSIONS NTAX=47;
        TAXLABELS
            'A.queenslandica_crb'
            A.vastus
            'AnophelesD_Crb'
            'Apis_Crb_iso1'
            'Aplysia_Crb'
            'C.elegans_CRB1'
            'C.elegans_CRB3'
            'Caw_Crb1'
            'Caw_Crb2'
            'Chimpanzee_Crb1'
            'Chimpanzee_Crb2'
            'Danio_Crb1'
            'Danio_Crb2'
            'Danio_Crb3'
            'Daphnia_Crb'
            'Dog_Crb1'
            'Fruitfly_CrbB'
            'Gallus_Crb1'
            'Gallus_Crb2_iso12'
            'HUMAN_CRUM1'
            'HUMAN_CRUM2'
            'HUMAN_CRUM3'
            'MOUSE_CRUM1'
            'MOUSE_CRUM2'
            'MOUSE_CRUM3'
            'Macaca_Crb1'
            'Macaca_Crb2'
            'Macaca_Crb3'
            'Nasonia_Crb-iso1'
            'Nematostella_CrbA'
            'Nematostella_CrbB'
            'O.lobularis_crb'
            O.minuta
            'Opossum_Crb1'
            'Opossum_Crb2'
            'Opossum_Crb3'
            'S.ciliatum_crb'
            'Saccoglossus_CrbL'
            'Takifugu_Crb1'
            'Takifugu_Crb2'
            'Tribolium_Crb'
            'Trichoplax_CrbA'
            'Trichoplax_CrbB'
            'Urchin_Crb1'
            'Xenopus_Crb1'
            'Xenopus_Crb2'
            'Xenopus_Crb3'
            ;
END;

BEGIN CHARACTERS;
[! TreeBASE Matrix URI: http://purl.org/phylo/treebase/phylows/matrix/TB2:M45621]

	TITLE Character_Matrix_figure_5_tree;
	LINK TAXA = Taxa;
	DIMENSIONS NCHAR=71;
	FORMAT DATATYPE=Protein SYMBOLS= "A C D E F G H I K L M N P Q R S T V W Y" MISSING=? GAP= -;

MATRIX
[                               10        20        30        40        50        60        70 ]
[                                .         .         .         .         .         .         . ]
'A.queenslandica_crb'   LSIII-LAVVVFVLLLFLVVVV-VVV--GLRIVRRKSRRKGFYSPAAVERESE-----GTGGQRTDRERLL
A.vastus                LIGVV-LLIVITVVLIIALVVLWKYV--------SSYYRYDKYSPAKTEVQKG-SLGLIDI---ESEETLI
'AnophelesD_Crb'        IALIV-VPVVIGILTIAGALIG---T--FLVMARNKRATRGTYSPSAQEYCNP-RLEMDNVLKPPPEERLI
'Apis_Crb_iso1'         IAVIV-GPIVGCLFIIAAGSLV---A--LFMMARKKRATRGTYSPSAQEFSNP-RVEMDNVMKPPPEERLI
'Aplysia_Crb'           -ILIL-VPILGGLLFIALIVGA--IW--LLKSWREKRASHGVYSPSQQESSGS-RVELGNVLKKPPEERLI
'C.elegans_CRB1'        ISYLF-GPIIAVVIVFAILGCL---L--LFFVIRGNNAMHGHYSPSSHEFTQN-RMAMPTVIKLPPQERLI
'C.elegans_CRB3'        IAGIV-IAVVIGVLLIGVVGFF------AFKYVKDRRKNHGEYRPQFEEQHHA---KDLPYLQPPNVEGLI
'Caw_Crb1'              VFTTI-GSVTLALLLILFLAVV------ASVLASNKRATQGSYSPSRQEKDSS-RVEMWSVMDAPAAERLI
'Caw_Crb2'              LLEVA-VPAACACLLLLLLGLL---S--GILAARKRRQSEGTYSPSQQEVAGA-RLEMDSVLKVPPEERLI
'Chimpanzee_Crb1'       IFTTI-GSVTIALLLILLLAIV------ASVVTSNKRATQGTYSPSRQEKEGS-RVEMWNLMPAPAMERLI
'Chimpanzee_Crb2'       LLEVA-VPAACACLLLLLLGLL---S--GILAARKRRQSEGTYSPSQQEVAGA-RLEMDSVLKVPPEERLI
'Danio_Crb1'            LLLSI-SLVCVVLLLVVFGVTT------ALVIALNRRATRGTYSPSRQEKEGS-RVEMWNIVQPPPMERLI
'Danio_Crb2'            WLAIA-VPLACGCILLVAIGLI---F--MLMTARKKRQSEGTYSPSHQEVAGA-RLEMDSMLKVPPEERLI
'Danio_Crb3'            VAIVV-PTVVLGLLAILTAVLV---F--LFCVVKKKRQTEGTYRPSAEEQTGARSVEAPDALKLPKEERLI
'Daphnia_Crb'           LVAII-VPIVAALLLIALVGFV---V--FVMMARNKRATRGTYSPSRQEMFSP-RVEMGQVMKPPPEERLI
'Dog_Crb1'              VFTTI-GSVTTVLLLILFLAVV------ASVVASNKRATQGTYSPSRQEKEGS-RVEMWSMRPPPALERLI
'Fruitfly_CrbB'         IAIIV-IPVVVVLLLIAGALLG---T--FLVMARNKRATRGTYSPSAQEYCNP-RLEMDNVLKPPPEERLI
'Gallus_Crb1'           VFTSL-GSVTLA-LLILFLAVV------VSVIAANKRSTQGTYSPSRQEKDGA-RVEMWSMVQPPPIERLI
'Gallus_Crb2_iso12'     LIEVA-VPVACGSLLLLSIGLI---F--MILTARKRRQSEGTYSPSQQEVAGA-RLEMDSVLKVPPEERLI
'HUMAN_CRUM1'           IFTTI-GSVTVALLLILLLAIV------ASVVTSNKRATQGTYSPSRQEKEGS-RVEMWNLMPPPAMERLI
'HUMAN_CRUM2'           LLEVA-VPAACACLLLLLLGLL---S--GILAARKRRQSEGTYSPSQQEVAGA-RLEMDSVLKVPPEERLI
'HUMAN_CRUM3'           TAIIV-VFSLLAAL-LLAVGLA---L--LVRKLREKRQTEGTYRPSSEEQVGA-RVPPTPNLKLPPEERLI
'MOUSE_CRUM1'           IFTAV-GSGTLALFFILLLAGV------ASLIASNKRATQGTYSPSGQEKAGP-RVEMWIRMPPPALERLI
'MOUSE_CRUM2'           LLEVA-VPAACACLLLLLLGLL---S--GILAARKRRQSEGTYSPSQQEVAGA-RLEMDSVLKVPPEERLI
'MOUSE_CRUM3'           VAITV-VFSILGVL-LIAVGLF---L--LMRKLREKRQTEGTYRPSSEEQVGA-RAPPPPNLKLPPEERLI
'Macaca_Crb1'           IFTAI-GSVTLALLLILLLAIV------ASVVTSNKRATQGTYSPSRQEKEGS-RVEMWNLMPPPAMERLI
'Macaca_Crb2'           LLEVA-VPAACACLLLLLLGLL---S--GILAARKRRQSEGTYSPSQQEVAGA-RLEMDSVLKVPPEERLI
'Macaca_Crb3'           TAIIV-VFSILAIL-LLAVGLA---L--LVWKLREKRQTEGTYRPSSEEQVGA-RVPPTPNLKLPPEERLI
'Nasonia_Crb-iso1'      IAVIV-GPIVGILFLIAAGSLI---A--LFMMARKKRATRGTYSPSAQEFSNP-RVEMDNVMKPPPEERLI
'Nematostella_CrbA'     DVELG-LSIAFVLVVLIVALVI---L--YFYFRKKAAKESGKYYPSEEEYKGGYPMSPLDFDKLDKEEQLL
'Nematostella_CrbB'     -EMII-IGVVVGCVALILLVLL--------IVLLMKRASNGTYSPSKEEFGGG-RVELDSMMKKPNEERLI
'O.lobularis_crb'       IAGIV-IGIVVFLILLLLLVLL----------LVRRRQHSGAYSPTETELAIG---NLLAEQERDPPEKLI
O.minuta                ----I-SILSVCLILIAILAILIAVISCYYSCRYWKSRKYNEYSPAETEVYKK-AAGLIDI---ESEETLI
'Opossum_Crb1'          IFTAI-GSITLAVLLILFLAVV------ASFIASNKRANQGTYSPSRQEKEGS-RVEMWNMVQPPPMERLI
'Opossum_Crb2'          LIEVV-VPVACGCLLLLLIGLL---S--GVLAARKRRQSEGTYSPSQQEVAGA-RLEMDSVLKVPPEERLI
'Opossum_Crb3'          TTIIY-ISSVLCIL-LLATLFL---F--LGQRLLDKRKCSGTYRPSDEEQVGD-CIPRQS-GKEPPKERLI
'S.ciliatum_crb'        TTTIV-IIVVVVVVVLLILLVL---M--GLYRRKQRGKLSGSYSPSSVEGNGA-DLDDLDV----EEERLI
'Saccoglossus_CrbL'     -VIII-GAALGGLVFIMLIILL---V--FLFSVRSKRATRGTYSPSRQEMTGS-RVEMGNVLKPPPEERLI
'Takifugu_Crb1'         -LLSV-SLVSVLLLVALVLTSV------GLAAALGRRATHGTYSPSRQEKEGS-RVEMWSITQTPPRERLI
'Takifugu_Crb2'         WLVVA-IPLTTLCMLLAILVVF---F--LIMTARKKRQSEGTYSPSSQEVAGA-RLEMGSVLKVPPEERLI
'Tribolium_Crb'         ILYII-IPIVLILSVGIAIGLA---V--LVNVARSKRATRGTYSPSAQEFCNP-RVELDHVLKPPPEERLI
'Trichoplax_CrbA'       AVAIA-VPILLVIIIIVVAIVI---F--RFYYKPRARKATGKYRPRETEQGSP-----MSTLESEGADRLI
'Trichoplax_CrbB'       -VGAT-IGIAMGVTGFILIVII---I--VVYVVIKNRAKQGRFNPSKQEEFG--RFHMADMSKLPPRERLI
'Urchin_Crb1'           WIIIG-ASLAAAVVLIIVIILL--SF--FVCSVRKKRATQGSYSPSRQEMTGS-FVEMDNVLKMPPEERLI
'Xenopus_Crb1'          VFTAV-ASVVLALFFIVCAGLC------IFIAISGMRSSQGAYSPSRQEKESS-RVEMWNIVQPPPLERLI
'Xenopus_Crb2'          ASTLVGSAIGTGMLFILLSVIT---A--VLVTMRNKRATQGTYSPSRQEKDGA-RVEMWNVLKLPPTERLI
'Xenopus_Crb3'          AAIIV-PCVVGGL--ILIGILA---F--IIIKIRERRRTEGTYRPSSEEHKEP-RVEPNMALKLPPEERLI
;
END;