#NEXUS
[saved by seaview on Fri Jun 27 12:54:05 2014]
BEGIN DATA;
	Title 'Alignment from "E5-SMAD-76.nexus"';
  DIMENSIONS NTAX=76 NCHAR=115;
  FORMAT DATATYPE=PROTEIN
  GAP=-
  ;
MATRIX
[1] 'Hydra magnipapillata Smad4'
GYNLYRSDRNDVHRG-------------------GRGIKLDRRGE--GDVWVRCLSDQSV
FVSSYFLD------RQAGRSPGDAVHKIYPQ--AYIKVFDLRMCYEQMKQQAQAA
[2] 'Cladonema pacificum Smad4'
----------------------------------GRGIQLDRRGE--GDVWVRCLSDQSV
FVSSYYLD------RQAGRSPGDAVHKIYPQ--AYIKVFDLRMCFEQMKQQAQAA
[3] 'Lottia gigantea Smad4'
IDRFCLGQLSNVHRTEASERA---------RLHIGKGVQLDYRGE--GDVWIRCVSDHSV
FVQSYYLD------REAGRAPGDAVHKIYPS--AYIKVFDIRQCHRQMQQQAATA
[4] 'Ciona intestinalis Smad4'
-NRFCLGQLSNVHRTEASEKA---------RLHIGKGVQLVCHGE--GDVWVKCLSDHAV
FVQSYYLD------REAGRSPGDAVHKIYPN--AYIKVFDLRQCHRQMQQQANTA
[5] 'Danio rerio Smad4'
-DRFCLGQLSNVHRTEAIERA---------RLHIGKGVQLECKGE--GDVWVRCLSDHAV
FVQSYYLD------REAGRAPGDAVHKIYPS--AYIKVFDLRQCHRQMQQQAATA
[6] 'Mus musculus Smad4'
-DRFCLGQLSNVHRTEAIERA---------RLHIGKGVQLECKGE--GDVWVRCLSDHAV
FVQSYYLD------REAGRAPGDAVHKIYPS--AYIKVFDLRQCHRQMQQQAATA
[7] 'Branchiostoma floridae Smad4'
-DRFCLGQLSNVHRTEASERA---------RLHIGKGVQLDLRGE--GDVWVRCLSDHAV
FVQSYYLD------REAGRAPGDAVHKIYPS--AYIKVFDLRQCHRQMQQQAATA
[8] 'Oscarella carmela Smad4'
-GRFCLGQLSNVHRAEQIERV---------RLHIGRGIQLDSRSN--GDVWLRCLSEHSV
YVQSYYLD------QEAGRAPGDAVHKIYPN--AYIKI--------------ANE
[9] 'Saccoglossus kowalevskii Smad4'
-DRFCLGQLSNVHRTEASERA---------RLHIGRGVQLDLRGE--GDVWVRCLSDHAV
FVQSYYLD------REAGRAPGDAVHKIYPN--AYIKVFDLRQCHQQMRQQAATA
[10] 'Acropora millepora Smad4'
-SRFCLGQLSNVHRTDASEKA---------RLHIGKGVQLDLRGE--GDVWVRCLSEHSV
FVQSYYLD------REAGRCPGDAVHKIYPS--AYIKVFDLRQCYHQIKQQAHAA
[11] 'Acropora digitifera Smad4'
-SRFCLGQLSNVHRTDASEKA---------RLHIGKGVQLDLRGE--GDVWVRCLSEHSV
FVQSYYLD------REAGRCPGDAVHKIYPS--AYIKVFDLRQCYHQIKQQAHAA
[12] 'Nematostella vectensis Smad4'
-NRFCLGQLSNVHRTEASERA---------RLHIGKGVQLDVRGE--GDVWVRCLSEHSV
FVQSYYLD------REAGRCPGDAVHKIYPS--AYIKVFDLRALLPQMGQTSVGV
[13] 'Tribolium castaneum Smad4'
-NRFCLGALSNVHRTDQSERA---------RLHIGKGVQLDLRGE--GDVWLRCLSDHSV
FVQSYYLD------REAGRQPGDAVHKIYPS--AYIKVFDLRQCHNQMTTQAATA
[14] 'Drosophila melanogaster Smad4'
-NRFCLGALSNVHRTEQSERA---------RLHIGKGVQLDLRGE--GDVWLRCLSDNSV
FVQSYYLD------REAGRTPGDAVHKIYPA--ACIKVFDLRQCHQQMHSLATNA
[15] 'Trichoplax adhaerens Smad4'
-NRFCLGQLSNVHRTKESERA---------RLHIGKGVRLECHGE--GDVWLSCLSEHSV
FVQSYYLD------REAGRGPFDYVHKVYPK--AYIKVFDLQLCYQQMQQEASKA
[16] 'Mnemiopsis leidyi Smad4'
-NRFCLGQLSNVHRTEASEKA---------RLHVGKGVKLTLSGE--GDVWLECQSQHPV
FVQSQYLD------KEAKRAPGDAVHKIFPG--THLKVFDLHDCYDTIKNKAQKA
[17] 'Amphimedon queenslandica Smad4b'
-DRFCLGRLSNVHRTEASERA---------RLHIGKGIIIEEKNE--TEVWIRCVSEHSV
FVQSYYLD------YQAGRALGDAVHKIYPK--AYIKVFDLRHCYEEMQKQAHEA
[18] 'Amphimedon queenslandica Smad4a'
-DRFCLGRLSNVHRTEPSKRV---------ISHIEKGIVIEEKNE--TEVWIRCVSRHSV
FVQSNYLD------YQAGQAQGDAVHKIYPN--AYIKVFDLSYY-----------
[19] 'Hydra magnipapillata Smad2/3'
QDRFCLGLLSNINRTEQIELS---------RRHIGKG-VRLYYFG--GEVFAECLSNSSI
FVQSSNCN------RRYGWHP-ATVCKIPPS--CNLKIFNNQEFAELLSQCVPRG
[20] 'Cladonema pacificum Smad2/3b'
VERFCLGLLSNINRTEQVEES---------RRHIGKG-VRLYYFG--GEVFAECLSKGSI
FVQSANCN------RRYGWHP-ATVCKIPSG--CNLKIFNNQEFAGLLSESVNKG
[21] 'Cladonema pacificum Smad2/3a'
LDRFCLGLLSNINRTEQVEEC---------RRAIAKG-VRLYYFG--GEVFAECLSVSSI
FVQSANCN------RRYGWHP-ATVCKIPSG--CNLKIFNNQEFAKLLSERVPLG
[22] 'Ciona intestinalis Smad2/3a'
SERFCLGLLSNINRNQQIELT---------RRHVGKG-VRLYYIG--GEVFAECLGESSI
FVQSPNCN------NRYGWHP-ATVVKIPPG--CNLKIFNNQEFAALLSQLVNQG
[23] 'Drosophila melanogaster Smad2/3'
SERFCLGLLSNVNRNEVVEQT---------RRHIGKG-VRLYYIG--GEVFAECLSDSSI
FVQSPNCN------QRYGWHP-ATVCKIPPG--CNLKIFNNQEFAALLSQSVSQG
[24] 'Danio rerio Smad3'
SERFCLGLLSNVNRNAAVELT---------RRHIGRG-VRLYYIG--GEVFAECLSDSAI
FVQSPNCN------QRYGWHP-ATVCKIPPG--CNLKIFNNQEFAALLAQSVNQG
[25] 'Mus musculus Smad3'
SERLCLGLLSNVNRNAAVELT---------RRHIGRG-VRLYYIG--GEVFAECLSDSAI
FVQSPNCN------QRYGWHP-ATVCKIPPG--CNLKIFNNQEFAALLAQSVNQG
[26] 'Danio rerio Smad2'
SERFCLGLLSNVNRNATVEMT---------RRHIGRG-VRLYYIG--GEVFAECLSDSAI
FVQSPNCN------QRYGWHP-ATVCKIPPG--CNLKIFNNQEFAALLAQSVNQG
[27] 'Mus musculus Smad2'
SERFCLGLLSNVNRNATVEMT---------RRHIGRG-VRLYYIG--GEVFAECLSDSAI
FVQSPNCN------QRYGWHP-ATVCKIPPG--CNLKIFNNQEFAALLAQSVNQG
[28] 'Lottia gigantea Smad2/3'
SERFCLGLLSNVNRTQQVEMT---------RRYIGKG-VRLYYIG--GEVFAECLSENAV
FVQSPNCN------QRYGWHP-ATVCKIPPG--CNLKIFNNQEFAALLAQSVNQG
[29] 'Saccoglossus kowalevskii Smad2/3'
SERFCLGLLSNINRNQTIELT---------RRHIGKG-VRLYYIG--GEVFAECLSESSI
FVQSPQCN------LRYGWHP-ATVCKIPPG--CNLKIFNNQEFAALLSQSVNQG
[30] 'Branchiostoma floridae Smad2/3'
SERFCLGLLSNVNRNHVIEQT---------RRHIGKG-VRLYYIG--GEVFAECLSESSV
FVQSPNCN------QRYGWHP-ATVCKIPPG--CNLKIFNNQEFAQLLSQSVSQG
[31] 'Ciona intestinalis Smad2/3b'
SERFCLGLLSNINRTQHVEIT---------RRHVGKG-VRLYYIA--GEVFAECLSDSAI
FVQSPNCN------QRYGWHP-ATVVKIPPG--CHLKIFNNQEFAALLSQSVNQG
[32] 'Acropora millepora Smad2/3'
SDRFCLGLLSNINRNPQIEMT---------RKHIGKG-VRLYYIG--GEVFAECLSDSSI
FVQSPNCN------QRYGWHP-ATVCKIPPG--CNLKIFNNQEFAQLLSQSVNQG
[33] 'Acropora digitifera Smad2/3'
SDRFCLGLLSNINRNPQIEMT---------RKHIGKG-VRLYYIG--GEVFAECLSDSSI
FVQSPNCN------QRYGWHP-ATVCKIPPG--CNLKIFNNQEFAQLLSQSVNQG
[34] 'Nematostella vectensis Smad2/3'
SDRFCLGLLSNINRNPPIEMT---------RKHIGKG-VRLYYIG--GEVFAECLSDSSI
FVQSPNCN------QRYNWHP-ATVCKIPPG--CNLKIFNNQEFAQLLSQSVNQG
[35] 'Trichoplax adhaerens Smad2/3'
SERFCLGLLSNVNRDPTVEMT---------RREIGKG-VRLCYVH--GEVFAECCSKHAV
FVQSPNSN------RRYGWHP-AAVCKIPPG--SSLRIFNSQEFANLLSQSVTQG
[36] 'Mnemiopsis leidyi Smad2/3-like'
NRRFCLGQLTNINRTPPVEKC---------RKQIGKG-IHLQYVQ--GEVHAVCLSDSSI
FVQSQNCN------QRNGWHP-NTVCKIPTG--CHLNIFNNTEFANLLSQSVGHG
[37] 'Ciona intestinalis Smad1/5'
SNRFCLGQLSNVNRNSTIENT---------RRHISKG-VHLYYVG--GEVYAECLSDSSI
FVQSRNCN------YHHGFHP-TTVCKIPPS--CSLKIFNNQEFAALLSQSVNHG
[38] 'Drosophila melanogaster Smad1'
SDRCCLGQLSNVNRNSTIENT---------RRHIGKG-VHLYYVT--GEVYAECLSDSAI
FVQSRNCN------YHHGFHP-STVCKIPPG--CSLKIFNNQEFAQLLSQSVNNG
[39] 'Tribolium castaneum Smad1'
SDRFCLGQLSNVNRNSTIENT---------RRHIGKG-VHLYYVN--GEVYAECLSDSPI
FVQSRNCN------HHHGFHP-SAVCKIPAG--CSLRIFNNAEFAQLLSQCVNHG
[40] 'Lottia gigantea Smad1/5'
ADRFCLGLLSNVNRNSTIENT---------RRHISKG-VHLYYVG--GEVFAECLSDSSI
FVQSRNCN------YHHGFHP-TTVCKIPPG--CSLKIFNNQEFATLLSQSVNHG
[41] 'Mus musculus Smad8'
RNRFCLGLLSNVNRNSTIENT---------RRHIGKG-VHLYYVG--GEVYAECVSDSSI
FVQSRNCN------YQHGFHP-ATVCKIPSG--CSLKVFNNQLFAQLLAQSVHHG
[42] 'Mus musculus Smad9'
RNRFCLGLLSNVNRNSTIENT---------RRHIGKG-VHLYYVG--GEVYAECVSDSSI
FVQSRNCN------YQHGFHP-ATVCKIPSG--CSLKVFNNQLFAQLLAQSVHHG
[43] 'Danio rerio Smad9'
KNRFCLGLLSNVNRNSTIEHT---------RRHIGKG-VHLYYVG--GEVYAECLSDSSI
FVQSRNCN------YQHGFHP-TTVCKIPSG--CSLKIFNNQLFAQLLSQSVNHG
[44] 'Danio rerio Smad5'
KNRFCLGLLSNVNRNSTIENT---------RRHIGKG-VHLYYVG--GEVYAECLSDTSI
FVQSRNCN------YHHGFHP-TTVCKIPSG--CSLKIFNNQEFAQLLAQSVNHG
[45] 'Mus musculus Smad5'
KSRFCLGLLSNVNRNSTIENT---------RRHIGKG-VHLYYVG--GEVYAECLSDSSI
FVQSRNCN------FHHGFHP-TTVCKIPSS--CSLKIFNNQEFAQLLAQSVNHG
[46] 'Danio rerio Smad1'
RNRFCLGLLSNVNRNSTIENT---------RRHIGKG-VHLYYVG--GEVYAECLSDSSI
FVQSRNCN------YHHGFHP-TTVCKIPSR--CSLKIFNNQEFAELLAQSVNHG
[47] 'Mus musculus Smad1'
KNRFCLGLLSNVNRNSTIENT---------RRHIGKG-VHLYYVG--GEVYAECLSDSSI
FVQSRNCN------YHHGFHP-TTVCKIPSG--CSLKIFNNQEFAQLLAQSVNHG
[48] 'Acropora millepora Smad1/5/8b'
SERFCLGLLSNVNRNSTIEST---------RRHIGKG-VHLYYVG--GEVYAECLSDSAI
FVQSRNCN------HSHGFHP-TTVCKIPSG--CTLKIFNNQEFAQLLSQSVNYG
[49] 'Acropora digitifera Smad1/5/8'
SERFCLGLLSNVNRNSTIEST---------RRHIGKG-VHLYYVG--GEVYAECLSDSAI
FVQSRNCN------HSHGFHP-TTVCKIPSG--CTLKIFNNQEFAQLLSQSVNYG
[50] 'Nematostella vectensis Smad1/5'
SERFCLGLLSNVNRNSTIENT---------RRHIGKG-VHLYYVG--GEVYAECLSDSAI
FVQSRNCN------HSHGFHP-TTVCKIPSG--CTLKIFNNQEFAQLLSQSVNYG
[51] 'Acropora millepora Smad1/5/8a'
SERFCLGLLSNVNRNSTIEST---------RRHIGKG-VHLYYVG--GEVYAECLSDSAI
FVQSRNCN------HSHGFHP-TTVCKIPSG--CTLKIFNNQEFAQLLSQSVNYD
[52] 'Saccoglossus kowalevskii Smad1/5'
SDRFCLGLLSNVNRNSTIENT---------RRHIGKG-VHLYYVG--GEVYAECLSDSSI
FVQSRNCN------YTHGFHP-TTVCKIPPG--CSLKIFNNQEFAALLSQSVNHG
[53] 'Hydra magnipapillata Smad1/5'
SDRFCLGGMSNVNRNSTIENT---------RRHISKG-VHLYYVG--GEVFAECLSDSAV
FVQSKNCN------YHHGFHP-STVCKIPPQ--CTLKIFNNQEFAQLLSQSVNHG
[54] 'Cladonema pacificum Smad1/5/8b'
SDRFCLGGMSNVNRNSTIENT---------RRHISKG-VHLYYVG--GEVFAECLSDSAI
FVQSRNCN------YHHGFHP-TTVCKIPPQ--CTLKIFNNQEFAQLLSQSVNHG
[55] 'Cladonema pacificum Smad1/5/8a'
SDRFCLGGMSNVNRNSTIENT---------RRHISKG-VHLYYVG--GEVFAECLSDSAI
FVQSRNCN------YHHGFHP-TTVCKIPPQ--CTLKIFNNQEFAQLLSQSVNHG
[56] 'Oscarella carmela Smad1/5/8'
SDRFCLGLLSNVNRNSTIENT---------RRHIGRG-VHLYYVG--GEVFAECLSDSAV
FVQSRNCN------HHHGFHP-STVCKIPHG--CSLKIFNNQEFAELLSRNVNEG
[57] 'Trichoplax adhaerens Smad1/5'
ADRFCLGLLSNVNRNSTIENT---------RRHIGKG-VHLYYVG--GEVYAECLSESSI
FVQSRNCN------YHHNFHP-TTVCKIPSS--CSLKIFDNQDFAALLSESVSKG
[58] 'Amphimedon queenslandica Smad1/5b'
GDRFCLGLLSSVHRNSTIENT---------RRHIGKG-VHLVYVN--GEVFAECLSENSI
FVQSRNCN------SSHGFHL-TTVCKIPPG--CSLKIFNNQDFASMLAQSVHQG
[59] 'Amphimedon queenslandica Smad1/5a'
GERFCLGQFSSIRRSGLIENT---------RRHIGKG-VHLVYVN--GEVIADCLSENAI
FVHSRNNN------FSNGFHP-TTVCKIPPG--CSLRIFNNQDFASTLAESVTEG
[60] 'Mnemiopsis leidyi R-Smadb'
KDRYCIGLLSNVARNPMIEAT---------RKHINRG-VKLTKVN--GEVHAECLSDSAI
FVQSRNCN------RERGFHP-STVCKLPPG--YKLRIFNYSDFYRLLQDNVHNG
[61] 'Mnemiopsis leidyi R-Smada'
QQRFCLGQLSNVSRNNTVEKT---------RKHIGRG-VKISFED--NKVYIECLGDSAV
FVQSRNSN------KEYGFHP-STVVKIQSG--VKLKIFCHKLFHEILTQQLTEG
[62] 'Amphimedon queenslandica Smad2/3'
TDRFCLGKMCNVNRDNITIQA---------RKHIGQG-IKLMYIG--GEVHLECLGKNAV
FVQAPNAN------LRNRWES-ATVVKVPQG--CLLDLFNSQDFAKRLADAVHLG
[63] 'Amphimedon queenslandica R-Smadb'
SSRYCLGRITNVNRNETINKA---------RKFIGNG-IIIRYRN--HELVVENHGSAAV
FVNSKMTN------FEHCLPR-STVIKVPNN--YYLKIFDTNLFSYVLSKTAKDG
[64] 'Amphimedon queenslandica R-Smada'
SSRYCLGRITNVNRNEAINKA---------RKFIGNG-IIIRFRN--HELVVENHGSAAV
FVNSKMTN------FEHCLPR-STVIKVPNN--YYLKIFDTSLFSYVLSKTAKDG
[65] 'Tribolium castaneum Smad5'
-DRFNLFEKENAGREWTVKNT---------RQQIGRG-ITLHYVK--GQIYVQLWSDSDL
YVNSRFYN------RLKNYPG-GTICKLSPFRCRHMKLFRDDEFHEMLSAEVAKG
[66] 'Ciona intestinalis Smad6/7'
--GFCLSAVS----SQTSRSA-------KVRRLIGHG-VTIGIDPTLQEASLYNRSDYPV
FVNSPVLE------PIPSRS--QLVHKVLPG--ECCRIFSHEVAADLKRLHSHHV
[67] 'Mnemiopsis leidyi Smad6/7'
--GLDLSKIANDDVSRDEVTA-------RVRKHIGSG-ILVSLEE--DGIWLYNRSEISI
FVQSPTMS------TGDKSR--LQVHKVLPG--YALNSY--------HFAHHSTV
[68] 'Branchiostoma floridae Smad6/7'
--GFCLGLLSSS-ESHSENVV-------RTRKKIGYG-LTLSKEP--DGVWAYNRSSHAI
FVNSPTLD------IPNSRT--LIVRKIPPG--FSIKIFDYGRS-EMLQRTSNPD
[69] 'Lottia gigantea Smad6'
--GMSLEILQN--KPNLESVK-------RTREKIGFG-IILSKEA--DGVWVYNRSSYPI
FVNSPTLD------DPESRT--LIVRKVLPG--YSIKIYDFELA-KELELSRDPA
[70] 'Saccoglossus kowalevskii Smad6'
--GLCLGLLDR--ECRTESVI-------RTRTKIGYG-VTISREQ--DGVWAYNRSNHAM
FVNSPTLD------TPNSRT--LSVWKVSPG--YSIRIFDYEKS-ELLRRTRNPE
[71] 'Mus musculus Smad6'
--GFCLGQLNL--EQRSESVR-------RTRSKIGFG-ILLSKEP--DGVWAYNRGEHPI
FVNSPTLD------APGGRA--LVVRKVPPG--YSIKVFDFERS-GLLQH--AD-
[72] 'Tribolium castaneum Smad6/7'
--GLSLETLAQQNCNAPESVR-------HGRCKIGLG-VTLSHEG--GSVWVYNRSENPI
FVNSVTLD------SADS----PLPTRVPAE--QCLCVYDPQK--AAAHRTCWDF
[73] 'Drosophila melanogaster Smad6/7'
--EVDSMCLRDLTPAGNQIHS----VVPKARHTVGLG-VTLSLEN--GDVWIYNRGNTTI
FVDSPTLS------ENLDR-----VCKVMPG--YCLKAFETNRA-ELLSMRDHGH
[74] 'Trichoplax adhaerens Smad6/7'
--GFWLGALNRDGVSGNISNTDSNQCDSRVFHRIGYG-LQLSRED--DSVWIYNRSEHPL
YVNSPLYN------KNIQSTHNTEVKKVQPG--YSLKVFNYARV-DMPQQIRP--
[75] 'Nematostella vectensis Smad6/7'
--GFCLAGLDRNQNVSDGTKR--------ARNHVGFG-LQLSREE--DGIWIYNRSEYAV
FANGTTFPYVTTTPSAS---QNITVTKVPPG--FSLKIYDYNHS--PATCRTFEG
[76] 'Acropora digitifera Smad6/7'
--GFCLADLNRSSDVSEGTKR--------VRSQIGYG-LQLTRER--EEIWIYNRSNFSL
FANGPTLTFSDVNIPGGKLRHNIVVHKVPPG--CSLKVFDYKLT--PQVCRAIDS
;
END;

BEGIN TREES;
	Title 'Trees from "E5-SMAD-76.nexus"';
  TREE 'PhyML ML tree' = [PhyML LG+G4, 500 bootstrap replicates](((((((((((((((((((((((((('Cladonema pacificum Smad1/5/8a':0.0,'Cladonema pacificum Smad1/5/8b':0.0)[&label=419]:1.0E-6,'Hydra magnipapillata Smad1/5':0.036954)[&label=474]:0.082109,'Lottia gigantea Smad1/5':0.018316)[&label=151]:0.020307,'Ciona intestinalis Smad1/5':0.037391)[&label=133]:0.01271,'Saccoglossus kowalevskii Smad1/5':0.012652)[&label=58]:1.0E-6,(('Amphimedon queenslandica Smad1/5a':0.295398,'Amphimedon queenslandica Smad1/5b':0.032485)[&label=475]:0.182262,'Trichoplax adhaerens Smad1/5':0.107812)[&label=137]:0.030026)[&label=23]:0.013191,(((('Mus musculus Smad1':0.0,'Danio rerio Smad5':0.012323)[&label=409]:1.0E-6,'Mus musculus Smad5':0.037111)[&label=141]:1.0E-6,'Danio rerio Smad1':0.03774)[&label=150]:4.0E-6,('Danio rerio Smad9':0.024517,('Mus musculus Smad9':0.0,'Mus musculus Smad8':0.0)[&label=500]:0.064076)[&label=338]:0.026401)[&label=361]:0.051468)[&label=49]:0.024568,((('Acropora millepora Smad1/5/8a':0.012181,'Acropora millepora Smad1/5/8b':0.0)[&label=191]:1.0E-6,'Acropora digitifera Smad1/5/8':0.0)[&label=369]:0.012244,'Nematostella vectensis Smad1/5':1.0E-6)[&label=497]:0.063809)[&label=93]:0.012718,('Tribolium castaneum Smad1':0.080785,'Drosophila melanogaster Smad1':0.048872)[&label=265]:0.022492)[&label=59]:1.0E-6,((('Amphimedon queenslandica Smad2/3':0.983561,'Trichoplax adhaerens Smad2/3':0.230265)[&label=126]:0.085902,((('Nematostella vectensis Smad2/3':0.025821,('Acropora digitifera Smad2/3':0.0,'Acropora millepora Smad2/3':0.0)[&label=341]:1.0E-6)[&label=427]:0.012478,(('Cladonema pacificum Smad2/3a':0.119654,'Cladonema pacificum Smad2/3b':0.076044)[&label=399]:0.107376,'Hydra magnipapillata Smad2/3':0.060961)[&label=472]:0.163008)[&label=136]:0.017549,((('Ciona intestinalis Smad2/3b':0.092937,'Ciona intestinalis Smad2/3a':0.055491)[&label=209]:0.038335,'Saccoglossus kowalevskii Smad2/3':0.038287)[&label=116]:0.016773,(('Lottia gigantea Smad2/3':0.078576,(('Mus musculus Smad2':0.0,'Danio rerio Smad2':0.0)[&label=377]:1.0E-6,('Mus musculus Smad3':0.012879,'Danio rerio Smad3':0.0)[&label=448]:0.026013)[&label=443]:0.027791)[&label=120]:0.028954,('Branchiostoma floridae Smad2/3':0.060313,'Drosophila melanogaster Smad2/3':0.013487)[&label=246]:0.043368)[&label=10]:0.01876)[&label=51]:0.038214)[&label=83]:0.026048)[&label=214]:0.101214,'Mnemiopsis leidyi Smad2/3-like':0.456865)[&label=198]:0.086716)[&label=68]:0.047676,'Oscarella carmela Smad1/5/8':0.059589)[&label=285]:0.10305,'Tribolium castaneum Smad5':1.633726)[&label=109]:0.087946,'Mnemiopsis leidyi R-Smadb':0.441317)[&label=204]:0.116348,('Mnemiopsis leidyi R-Smada':0.256932,('Amphimedon queenslandica R-Smada':0.036316,'Amphimedon queenslandica R-Smadb':4.0E-6)[&label=499]:1.262338)[&label=212]:0.211481)[&label=328]:0.77445,(('Ciona intestinalis Smad6/7':1.087156,('Mnemiopsis leidyi Smad6/7':1.134047,'Drosophila melanogaster Smad6/7':1.429527)[&label=181]:0.383149)[&label=122]:0.134216,((((('Saccoglossus kowalevskii Smad6':0.325633,'Branchiostoma floridae Smad6/7':0.212543)[&label=362]:0.097807,'Lottia gigantea Smad6':0.702721)[&label=188]:0.073519,'Mus musculus Smad6':0.31718)[&label=340]:0.234652,('Trichoplax adhaerens Smad6/7':0.984857,('Acropora digitifera Smad6/7':0.436129,'Nematostella vectensis Smad6/7':0.623019)[&label=483]:0.853912)[&label=149]:0.230286)[&label=87]:0.20523,'Tribolium castaneum Smad6/7':1.449706)[&label=102]:0.259125)[&label=496]:1.111575)[&label=485]:0.6531,'Mnemiopsis leidyi Smad4':0.25689)[&label=210]:0.239152,(('Amphimedon queenslandica Smad4a':0.278277,'Amphimedon queenslandica Smad4b':0.011703)[&label=489]:0.341378,'Oscarella carmela Smad4':0.332988)[&label=44]:0.035625)[&label=14]:3.0E-6,'Trichoplax adhaerens Smad4':0.203382)[&label=56]:0.086197,'Ciona intestinalis Smad4':0.073253)[&label=63]:0.040552,('Mus musculus Smad4':0.0,'Danio rerio Smad4':0.0)[&label=484]:0.025317)[&label=95]:0.029519,('Branchiostoma floridae Smad4':1.0E-6,'Saccoglossus kowalevskii Smad4':0.053006)[&label=132]:1.0E-6)[&label=27]:0.013217,'Lottia gigantea Smad4':0.056107)[&label=82]:0.023102,('Drosophila melanogaster Smad4':0.127373,'Tribolium castaneum Smad4':0.043855)[&label=392]:0.081048)[&label=213]:0.060767,'Nematostella vectensis Smad4':0.175138)[&label=198]:0.047183,('Acropora millepora Smad4':0.0,'Acropora digitifera Smad4':0.0)[&label=461]:0.04523)[&label=500]:0.456409,'Cladonema pacificum Smad4':0.010962,'Hydra magnipapillata Smad4':0.064389);
  TREE 'IQPNNI ML consensus tree' = [IQPNNI WAG+G4, 100 bootstrap replicates, relative majority consensus]('Hydra magnipapillata Smad4':0.11115,(((('Nematostella vectensis Smad6/7':0.72496,'Acropora digitifera Smad6/7':0.55534)100:1.66728,'Ciona intestinalis Smad6/7':1.95480,'Mnemiopsis leidyi Smad6/7':2.13958,'Branchiostoma floridae Smad6/7':0.34163,'Lottia gigantea Smad6':0.69247,'Saccoglossus kowalevskii Smad6':0.54443,'Mus musculus Smad6':0.46031,'Tribolium castaneum Smad6/7':1.73150,'Drosophila melanogaster Smad6/7':2.68247,'Trichoplax adhaerens Smad6/7':1.39424)100:1.90130,(('Amphimedon queenslandica R-Smadb':0.00531,'Amphimedon queenslandica R-Smada':0.03528)100:1.80248,(('Cladonema pacificum Smad2/3b':0.12296,'Cladonema pacificum Smad2/3a':0.22267)51:0.06868,'Hydra magnipapillata Smad2/3':0.10751)100:0.37535,('Amphimedon queenslandica Smad1/5b':0.01366,'Amphimedon queenslandica Smad1/5a':0.27695)97:0.38886,((('Acropora millepora Smad1/5/8b':0.00001,'Acropora digitifera Smad1/5/8':0.00001)100:0.05528,'Acropora millepora Smad1/5/8a':0.05670)96:0.05561,'Nematostella vectensis Smad1/5':0.02490)95:0.23223,(('Cladonema pacificum Smad1/5/8b':0.00001,'Cladonema pacificum Smad1/5/8a':0.02727)82:0.00663,'Hydra magnipapillata Smad1/5':0.05883)88:0.23606,(('Danio rerio Smad3':0.00001,'Mus musculus Smad3':0.01765)98:0.03547,('Danio rerio Smad2':0.00001,'Mus musculus Smad2':0.00001)96:0.00001)86:0.16822,(('Acropora millepora Smad2/3':0.00001,'Acropora digitifera Smad2/3':0.00001)100:0.07904,'Nematostella vectensis Smad2/3':0.02060)72:0.19637,((('Mus musculus Smad8':0.00001,'Mus musculus Smad9':0.00001)100:0.08067,'Danio rerio Smad9':0.04591)90:0.06516,(('Mus musculus Smad5':0.02489,'Mus musculus Smad1':0.00833)54:0.00548,'Danio rerio Smad5':0.03647,'Danio rerio Smad1':0.04474)44:0.03952)70:0.20043,(('Drosophila melanogaster Smad1':0.09258,'Tribolium castaneum Smad5':2.19366)50:0.00001,'Tribolium castaneum Smad1':0.11167)55:0.20412,('Ciona intestinalis Smad2/3a':0.07886,'Ciona intestinalis Smad2/3b':0.13146)46:0.18033,'Drosophila melanogaster Smad2/3':0.18991,'Lottia gigantea Smad2/3':0.21839,'Saccoglossus kowalevskii Smad2/3':0.17857,'Branchiostoma floridae Smad2/3':0.18593,'Trichoplax adhaerens Smad2/3':0.43796,'Mnemiopsis leidyi Smad2/3-like':0.58763,'Ciona intestinalis Smad1/5':0.31572,'Lottia gigantea Smad1/5':0.16709,'Saccoglossus kowalevskii Smad1/5':0.15453,'Oscarella carmela Smad1/5/8':0.27670,'Trichoplax adhaerens Smad1/5':0.27905,'Mnemiopsis leidyi R-Smadb':0.86268,'Mnemiopsis leidyi R-Smada':1.11849,'Amphimedon queenslandica Smad2/3':0.92797)74:0.84658)99:0.98560,('Amphimedon queenslandica Smad4b':0.00001,'Amphimedon queenslandica Smad4a':0.30638)99:0.56481,('Danio rerio Smad4':0.00001,'Mus musculus Smad4':0.00896)98:0.08708,('Tribolium castaneum Smad4':0.05063,'Drosophila melanogaster Smad4':0.15854)84:0.14885,(('Acropora millepora Smad4':0.00001,'Acropora digitifera Smad4':0.00001)100:0.05078,'Mnemiopsis leidyi Smad4':0.67010)45:0.18176,'Lottia gigantea Smad4':0.22515,'Ciona intestinalis Smad4':0.19239,'Branchiostoma floridae Smad4':0.08783,'Oscarella carmela Smad4':0.42784,'Saccoglossus kowalevskii Smad4':0.10924,'Nematostella vectensis Smad4':0.34540,'Trichoplax adhaerens Smad4':0.44947)100:1.29062,'Cladonema pacificum Smad4':0.00001);
  TREE 'BioNJ consensus tree' = [BioNJ WAG+G4, 100 bootstrap replicates, relative majority consensus]('Hydra magnipapillata Smad4':0.11383,(('Danio rerio Smad4':0.00001,'Mus musculus Smad4':0.00912)93:0.09316,('Amphimedon queenslandica Smad4b':0.00001,'Amphimedon queenslandica Smad4a':0.31839)83:0.57863,('Tribolium castaneum Smad4':0.05575,'Drosophila melanogaster Smad4':0.15722)61:0.14715,((((('Nematostella vectensis Smad6/7':0.71185,'Acropora digitifera Smad6/7':0.57323)93:1.66690,'Ciona intestinalis Smad6/7':2.01084,'Mnemiopsis leidyi Smad6/7':2.22326,'Branchiostoma floridae Smad6/7':0.34821,'Lottia gigantea Smad6':0.72961,'Saccoglossus kowalevskii Smad6':0.54413,'Mus musculus Smad6':0.46325,'Tribolium castaneum Smad6/7':1.75229,'Trichoplax adhaerens Smad6/7':1.39961)50:0.83856,'Drosophila melanogaster Smad6/7':1.85437)100:1.17495,(('Amphimedon queenslandica Smad1/5b':0.02546,'Amphimedon queenslandica Smad1/5a':0.27160)100:0.35060,((('Acropora millepora Smad1/5/8b':0.00001,'Acropora digitifera Smad1/5/8':0.00001)100:0.05659,'Acropora millepora Smad1/5/8a':0.05765)100:0.05186,'Nematostella vectensis Smad1/5':0.03242)100:0.14944,((('Mus musculus Smad8':0.00001,'Mus musculus Smad9':0.00001)100:0.08485,'Danio rerio Smad9':0.04367)95:0.08783,((('Mus musculus Smad5':0.02537,'Mus musculus Smad1':0.00850)59:0.00770,'Danio rerio Smad5':0.03502)40:0.00001,'Danio rerio Smad1':0.04352)92:0.02481)64:0.06420,('Drosophila melanogaster Smad1':0.10728,'Tribolium castaneum Smad1':0.10418)63:0.11010,(('Amphimedon queenslandica R-Smadb':0.00905,'Amphimedon queenslandica R-Smada':0.03231)100:1.33984,'Mnemiopsis leidyi R-Smada':0.58415)51:0.50756,((('Cladonema pacificum Smad1/5/8b':0.00001,'Cladonema pacificum Smad1/5/8a':0.02788)48:0.00821,'Hydra magnipapillata Smad1/5':0.05546)96:0.09051,'Oscarella carmela Smad1/5/8':0.17864)46:0.07936,((('Hydra magnipapillata Smad2/3':0.13634,'Cladonema pacificum Smad2/3a':0.23861)49:0.06851,'Cladonema pacificum Smad2/3b':0.09511)100:0.32674,(('Acropora millepora Smad2/3':0.00001,'Acropora digitifera Smad2/3':0.00001)100:0.07847,'Nematostella vectensis Smad2/3':0.02501)95:0.11398,('Ciona intestinalis Smad2/3a':0.08860,'Saccoglossus kowalevskii Smad2/3':0.02188)72:0.06078,((('Danio rerio Smad3':0.00001,'Mus musculus Smad3':0.01785)98:0.03592,('Danio rerio Smad2':0.00001,'Mus musculus Smad2':0.00001)93:0.00001)87:0.03294,'Lottia gigantea Smad2/3':0.07429)40:0.04536,'Drosophila melanogaster Smad2/3':0.11082,'Branchiostoma floridae Smad2/3':0.08688,'Ciona intestinalis Smad2/3b':0.22157,'Trichoplax adhaerens Smad2/3':0.38990,'Amphimedon queenslandica Smad2/3':0.92510)44:0.28211,'Mnemiopsis leidyi Smad2/3-like':0.59729,'Ciona intestinalis Smad1/5':0.19760,'Lottia gigantea Smad1/5':0.07746,'Saccoglossus kowalevskii Smad1/5':0.07830,'Trichoplax adhaerens Smad1/5':0.22835,'Mnemiopsis leidyi R-Smadb':0.88954,'Tribolium castaneum Smad5':2.51175)80:0.77576)100:0.97473,'Oscarella carmela Smad4':0.28714)52:0.15858,('Acropora millepora Smad4':0.00001,'Acropora digitifera Smad4':0.00001)45:0.23575,'Lottia gigantea Smad4':0.22602,'Ciona intestinalis Smad4':0.20312,'Branchiostoma floridae Smad4':0.09791,'Saccoglossus kowalevskii Smad4':0.10706,'Nematostella vectensis Smad4':0.34104,'Trichoplax adhaerens Smad4':0.45108,'Mnemiopsis leidyi Smad4':0.82366)100:1.31799,'Cladonema pacificum Smad4':0.00001);
END;