#NEXUS [!This data set was downloaded from TreeBASE, a relational database of phylogenetic knowledge. TreeBASE has been supported by the NSF, Harvard University, Yale University, SDSC and UC Davis. Please do not remove this acknowledgment from the Nexus file. Generated on November 11, 2026; 16:28 GMT TreeBASE (cc) 1994-2008 Study reference: Gallagher K.A., & Jensen P.R. 2015. Genomic insights into the evolution of hybrid isoprenoid biosynthetic gene clusters in the MAR4 clade of marine streptomycetes. BMC Genomics, 16(960). TreeBASE Study URI: http://purl.org/phylo/treebase/phylows/study/TB2:S18360] [ The following blocks are input data for analysis step 17336 ] BEGIN TAXA; TITLE TaxaForAnalysisStep17336; DIMENSIONS NTAX=90; TAXLABELS Aspergillus_terreus_NIH2624_EAU39467_PtfAt Botryotinia_fuckeliana_B05.10_EDN25735_PtfBf Sclerotinia_sclerotiorum_1980_EDN93598_PtfSs 'Streptomyces acidiscabies 84_104 2547553903' Streptomyces_aculeolatus_NRRL_18422_ABS50461_NapT8 Streptomyces_aculeolatus_NRRL_18422_ABS50462_NapT9 Streptomyces_anulatus_9663_CAX48655_PpzP_ Streptomyces_cinnamonensis_DSM_1042_ADQ43372_EpzP_ Streptomyces_cinnamonensis_DSM_1042_CAL34104_Fnq26 'Streptomyces coelicolor A3_2 637271461' Streptomyces_davawensis_JCM_4913_2562412110 'Streptomyces gancidicus BKS 13_15 2539351921' Streptomyces_griseoflavus_Tu4000_645416841 Streptomyces_lividans_TK24_645400867 Streptomyces_mobaraensis_NBRC_13819_2538963887 Streptomyces_niveus_DSM_40088_AAF67510_NovQ Streptomyces_roseochromogenes_oscitans_DS_12.976_AAN65239_CloQ Streptomyces_sp._303MFCol52_2521683528 Streptomyces_sp._303MFCol52_2521683684 Streptomyces_sp._CNB632_2561470561 Streptomyces_sp._CNB632_2561472124 Streptomyces_sp._CNB632_2561473002 Streptomyces_sp._CNB632_2561473004 Streptomyces_sp._CNB632_2561473755 Streptomyces_sp._CNB632_2561476030 Streptomyces_sp._CNB632_2561476124 Streptomyces_sp._CNB632_2561476125 Streptomyces_sp._CNH099_2516097927 Streptomyces_sp._CNH099_2516099186 Streptomyces_sp._CNH099_2516101115 Streptomyces_sp._CNH099_2516101746 Streptomyces_sp._CNH099_2516101748 Streptomyces_sp._CNH099_2516104298 Streptomyces_sp._CNH099_2516104521 Streptomyces_sp._CNH099_2516104522 Streptomyces_sp._CNH189_2515835839 Streptomyces_sp._CNH287_2524586714 Streptomyces_sp._CNH287_2524588539 Streptomyces_sp._CNP082_2527270384 Streptomyces_sp._CNP082_2527270866 Streptomyces_sp._CNP082_2527270867 Streptomyces_sp._CNQ329_2528489393 Streptomyces_sp._CNQ329_2528491298 Streptomyces_sp._CNQ329_2528491789 Streptomyces_sp._CNQ329_2528491790 'Streptomyces sp. CNQ509 AA958_12625 ' 'Streptomyces sp. CNQ509 AA958_12635 ' 'Streptomyces sp. CNQ509 AA958_12645' 'Streptomyces sp. CNQ509 AA958_18620' 'Streptomyces sp. CNQ509 AA958_24270 ' 'Streptomyces sp. CNQ509 AA958_24325' 'Streptomyces sp. CNQ509 AA958_30735' Streptomyces_sp._CNQ525_2562118558 Streptomyces_sp._CNQ525_2562121671 Streptomyces_sp._CNQ525_2562123443 Streptomyces_sp._CNQ525_2562123520 Streptomyces_sp._CNQ525_2562123521 Streptomyces_sp._CNQ766_2518002741_ Streptomyces_sp._CNQ766_2518005124 Streptomyces_sp._CNQ766_2518006200 Streptomyces_sp._CNQ766_2518006639 Streptomyces_sp._CNQ766_2518006640 Streptomyces_sp._CNQ865_2524593636_ Streptomyces_sp._CNQ865_2524596589 Streptomyces_sp._CNQ865_2524600624 Streptomyces_sp._CNQ865_2524600745 Streptomyces_sp._CNQ865_2524600746_ Streptomyces_sp._CNS335_2518010821 Streptomyces_sp._CNS335_2518010999 Streptomyces_sp._CNS335_2518013585 Streptomyces_sp._CNS335_2518013945 Streptomyces_sp._CNS335_2518014051 Streptomyces_sp._CNS654_2562084974_ Streptomyces_sp._CNT371_2516104881 Streptomyces_sp._CNT371_2516108106 Streptomyces_sp._CNT371_2516111586 Streptomyces_sp._CNT371_2516112034 Streptomyces_sp._CNT371_2516112035 Streptomyces_sp._CNX435_2561476450 Streptomyces_sp._CNX435_2561478010 Streptomyces_sp._CNX435_2561479929 Streptomyces_sp._CNX435_2561481643 Streptomyces_sp._CNY243_2518513180 Streptomyces_sp._CNY243_2518518536 Streptomyces_sp._CNY243_2518518703 Streptomyces_sp._CNY243_2518518936 Streptomyces_sp._CNY243_2518518937 'Streptomyces sp. Cl190 1ZB6_A NphB' Streptomyces_sp._KO3988_BAE78975_Fur7 Streptomyces_vitaminophilus_DSM_41686_2515785691 ; END; BEGIN CHARACTERS; [! TreeBASE Matrix URI: http://purl.org/phylo/treebase/phylows/matrix/TB2:M33800] TITLE MAR4_clade_of_marine_streptomycetes_Orf2_prenyltransferases; LINK TAXA = TaxaForAnalysisStep17336; DIMENSIONS NCHAR=400; FORMAT DATATYPE=Protein SYMBOLS= "A C D E F G H I K L M N P Q R S T V W Y" MISSING=? GAP= -; MATRIX [ 10 20 30 40 50 60 70 80 90 100 110 120 130 140 150 160 170 180 190 200 210 220 230 240 250 260 270 280 290 300 310 320 330 340 350 360 370 380 390 400] [ . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .] Aspergillus_terreus_NIH2624_EAU39467_PtfAt ----------------MIQQVQQAVFDPE----RFLVDIEETCRAIGAPYSQEKTLKVLEGFQASF-AR--GAVLWRITN--RPGDALNYRF-YERVSIDAVSCAVEAKLF--QPNHPLSELIVSWTALYPGAAQQSCDFDAEQGFSKIWVYL--GDMRPLSDILSAPHVPLSIRKHATTFYNL-GLE--LVRHVAADFTSNTINIYFRV-------QGLLTLERARSLVR---LSDPAYLLECGEVEE----MRRLLNPVGFTFAVTMDYSTGDIKRVGIYA------LKLAPGTYPAMDERLKATRAI--PLEK---QAYILLS---QGVLMA--KEVAAAFPVPSETA-AVNRPREVDVEVGVGVASFMFQPTTPIAPTVDVRDNVVVAVFHAVESP Botryotinia_fuckeliana_B05.10_EDN25735_PtfBf --------------MVVQAVSESLKFDQS----RFLNDIQILSAAINAPYSESTTKKVLSVFSDSF-HD--GVVLWRATD--RVGDALNYRF-YSRRPIDTVTIASSAGLLSPDVVSNLGRLVTSWSSLYDGLPEESCDFDAEKGLVKAWVYM--RGMRPLGDILSAEGVPESLKQHEERFKAL-ELE--KVRHVAVDYQKATVNLYFRA-------QGPISLQQATSFNALAGAGPPS--------QTQFLEMQEFLNAVGYTFAVTIRVDSGDIERVGYYALKL---PDRATKNWPV----------I--NAQL---EKFAQFA---PSYDRE--EMNAVAWSFGGTKR-YVKFERSYCGELVPLIKGWGTTLSS----------------------- Sclerotinia_sclerotiorum_1980_EDN93598_PtfSs --------------MVVQLISKPSKFSQS----RFLDDIRNLSAAINAPYSERTTIEALSVYSHSF-HN--GVVLWRVTD--RPGDALNYRF-YSREPIDTVSIAASAGLLSPDIANTLGKLVTSWSSLYDGTPEESCDFDAEKGLVKAWVYF--GGMRPLDDILGAEGVPESVRQHEKRFKEL-GLQ--KVRHVAVDYHKQTVNLYFRA-------QGPISFQQATAFNALAGAEPPS--------QSQFIEMREFLNAVGYTFAVTINIDSGDIERVGYYALKL---PERSAKKWPA----------I--NAQL---ERFVQFA---PSYDRE--EMNAVAWSFGERKT-YVKFERSYCGELIPLIKGWGTTLSS----------------------- 'Streptomyces acidiscabies 84_104 2547553903' ---------------------MNEAVH------ALHSAIDDAAGLLEVDYERGDVLRILNLYGGEL-AD--AVVAFRVSTGEGRAGELDCRFTIPDG-LDPYQLAVDNGLL-EKDGHPVSRLLAELSARCP-VDGYGIDFGVVGGFKKIWAVLPRTQLQDVRTLAALPSMPGSLAASLDFIDRH-GLGD-TVGLLGVDYRHRTVNIYFGE-----PPAGGIAPESVRAMLREVDQAEPS--------EQ----MLRLG-RQAFGVYVTLDWDSPAITRVCFAV------ATTDPASLPV---------QL--DDRI---RQFVRHV---QRADPE--TRFVYAVASQPDGE-YYKLQSYY--RWGAGVPDIMQLPDGALADPV----------------- Streptomyces_aculeolatus_NRRL_18422_ABS50461_NapT8 ---------------------------ME----GLYAAIEEASGLLDVAPSRDKVWPILSAYE--L-DK--VVVAFRVTT--RGSKDLDCRFTALPADVNPYRYAVSKGIA-EATDHPVGTLLDDVQANIP-VTAHGVDFGVVEGFRKTWTFLPGNDLQKLSKVAALPSMPPSLAENLDFYARY-GLDD-KNSMIGIDYPSRTVNVYFLQ-----FPDETREPETVRAMLRDLGLPEPS--------EQ----MLTLA-KQAVGIYTTLTWDSPKIQRITFAT------LVPDAEALPG---------RIAVEPSV---EKFARNV---PHTYPGP-VQGLYNVASYSGGE-YFKLQTYH--QLAEGSLEARVLLGAAGAGS------------------ Streptomyces_aculeolatus_NRRL_18422_ABS50462_NapT9 MVGSHTRISQNLIGIDCLECLVSGATGAE----KLYSAIEESARMVDAPFSRDKVWPTLSAFEGGFSDA--GGVILSLQAG-THVPEMEYSAQVSPGISDPYARALASGIL-TETDHPVSTVLAEIVSLAP-TSEHYIDCGIVGGFKKIYANFP-HDQQTVAALAGLPSMPRAVGGNAEFFARH-GLD--RVALIGVDYVNKTINLYFQVSA---ATAGNLDQKTVSAMLHETGMSEPS--------DA----MVAYA-CQAYRIYTTLSWDAEEILRIAFAPKPR---RGIDPADLPA---------RL--EPRI---EKFLRAT---PHKYPGA-LINATAAKWSPERE-VLDLAAHY--QVSAVQMKAIEAEEGQAS-------------------- Streptomyces_anulatus_9663_CAX48655_PpzP_ ---------------------MSESAELT----ELYSAIEETTRVVGAPCRRDTVRPILTAYEDVI-AQ--SVISFRVQTGTSDAGDLDCRFTLLPKDMDPYATALSNGLT-AKTDHPVGSLLEEVHRQFP-VDCYGIDFGAVGGFKKAWSFFRPDSLQSASDLAALPSMPSGVSENLGLFDRY-GMTD-TVSVVGFDYAKRSVNLYFTG-----ASPESFEPRGIQAILRECGLPEPS--------DE----LLRFG-EEAFAIYVTLSWDSQKIERVTYSV------NTPDPMALPV---------RI--DTRI---EQLVKDA---PLGSAG--HRYVYGVTATPKGE-YHKIQKYF--QWQSRVEKMLTADAG----------------------- Streptomyces_cinnamonensis_DSM_1042_ADQ43372_EpzP_ ---------------------MSESADLT----ELYSIIEKTAQVVDVTASHDKVWPILNAFQDVI-AD--SVISFRASTG-SSADDLDCRFTMLPKGLDPYARALEHGLT-PKTDHPVGSLLKEVHENLP-ITSCGVDFGVAGGFTKTWSFPSAEKLGKVSELVKLPSIPDAVAANRDFFEKW-GIAD-MVSTVGIDYSKRTMNLYFGGGVGDRVPAGVFEEKGVRAILGELGLAAPS--------EE----LLKFC-ERSFVIYVTLSWDSPKINRFTYSV------MTPEPLGLPV---------DL--APTF---ERLIKSA---PYDTEG--RNYVYGIASTPKGE-YHKIASYY--QWQKRVEKLLRSDG------------------------ Streptomyces_cinnamonensis_DSM_1042_CAL34104_Fnq26 --------------------MMSGTADLA----GVYAAVEESAGLLDVSCAREKVWPILAAFEDVL-PT--AVIAFRVATNARHEGEFDCRFTVP-GSIDPYAVALDKGLT-HRSGHPIETLVADVQKHCA-VDSYGVDFGVVGGFKKIWVYFPGGRHESLAHLGEIPSMPPGLAATEGFFARY-GLAD-KVDLIGVDYASKTMNVYFAA------SPEVVSAPTVLAMHREIGLPDPS--------EQ----MLDFC-SRAFGVYTTLNWDSSKVERIAYSV------KTEDPLELSA---------RL--GSKV---EQFLKSV---PYGIDT--PKMVYAAVTAGGEE-YYKLQSYY--QWRTDSRLNLSYIGGRS--------------------- 'Streptomyces coelicolor A3_2 637271461' -------------------MPTGRTTDLA----LFLSDLEAYAKLAEVTFDKRAVEQVVDVFAEQF-AT--GTITVRTTTHEAANRSVNFRYMYPDSPHDPVEIARAHGLL-PDADPAVMSLLAEVTEKIP-L-WWGLDASVGHGVQKVWAFF--EQPLEFGEIASLENTPHSLRDHRERFGEA-RID--RFAIMGFDFRDNTTNLYSEM-----VSPGYFEQEEVARMIRDVGSLPPD--------NE----EIERC-RGAINVYYTFDWNSPQARRLCFAV------PSRD-GEFPS---------HL--HPLA---ARFAAEA---PVQAER--RELIFNPTFGARGS-YLKMEADY--TGDAASRVFGYWNR------------------------ Streptomyces_davawensis_JCM_4913_2562412110 ---------------------MSGTVDVSVA--GFYSAIEKSAGLLDVTASREAVWPILTAFEDAL-PH--AVIAFRVATNARHEGDFDARFTLPKE-IDPYEVAVSKGLM-AKTDHPIGSLLADLQQLCP-IDSYGIDFGVTSGFKKIWVYFPAGEHETLERLTGLASMPRSLAQNLEFFTRH-GLAD-KVDVIGIDYRSRTMNAYLRA------PAECYERESVLTMHRELGLPSPS--------EQ----MFAFC-EKAFGIYTTHNWDSPEIERISYGV------KTENPMAYFA---------RL--GTKI---EHFVQSV---PYGVND--PKMVYAAVTSTGEE-YYKLQSYY--RWRSVSRLNAAYIAARDQENA----------------- 'Streptomyces gancidicus BKS 13_15 2539351921' -----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-----VRPGYFAQEDVASMIRDMGSHPAD--------DE----EVGRC-REAINVYYTFDWNSPRARRLCFAV------PSRE-GNFPS---------HV--HPLA---ARFAAEA---PVLTER--RQLIFNPTFGAHGK-YLKLEADY--TGDAASRVFGYWNR------------------------ Streptomyces_griseoflavus_Tu4000_645416841 ---------------------MSGTSEAD----EICSAVTETAGRLGIAFSRDKVWPILSAYGDAF-AH-AMPLAFRMATGPQHAGDVDCRFITHPKDRNPYPLAVSKGLT-PKTSHPVGTLLSEIEERFP-IDGYGIDFGVVNGFTKVYAGFAPQDLQNASKLVEIPAMPRSLAGNFDFFVRH-GLDD-KVAFVAVDYLHRTVNVYFND-----VPAACFESDGIRRMLRDLGLPGPS--------DR----MLGIG-GQAFGLYITLNWDSPAIERFCFGV------TTTDLSSLPV---------SI--EPQL---EKFAHCV---PYGGAD--RKFVYGVAAAPEGE-YYKLETHY--KWNPGTVAFI---------------------------- Streptomyces_lividans_TK24_645400867 -------------------MPTGRTTDLA----LFLSDLEAYAKLAEVTFDNRAVEQVVDVFAEQF-AT--GTITVRTTTHEAANRSVNFRYMYPDSPHDPVEIARAHGLL-PDADPAVMSLLAEVTEKIP-L-WWGLDASVGHGVQKVWAFF--EQPLEFGEIASLENTPHSLRDHRERFGEA-RID--RFAIMGFDFRDNTTNLYSEM-----VSPGYFEQEEVARMIRDVGSLPPD--------NE----EIERC-RGAINVYYTFDWNSPQARRLCFAV------PSRD-GEFPS---------HL--HPLA---ARFATEA---PVQAER--RELIFNPTFGARGS-YLKMEADY--TGDAASRVFGYWNR------------------------ Streptomyces_mobaraensis_NBRC_13819_2538963887 ---------------MSEADPISRSSAAR----ALCSAIEETAGLLEVDYVRDDVLRVLDVYGGEL-SR--AVVAFRVATGAHRADELDCRFTVPRD-VDPYRLAVDSGLL-EETDHPVARLLADLRDNCP-VDGYGIDFGVVGGFKKIWVVLPRTALHSVTELAGLPSMPHSLGKSLDFISRH-GLGD-TVGLLGVDYRNRTVNVYFGE-----PPAGGIAPESVRSMLREVDQAEPS--------EQ----MLRLG-RRAFGVYVTLGWDSPVIERICFAV------ATTDPASLPV---------EL--DERI---ERFVRHV---RRTDPD--TRFVYAVASQPDGE-YYKLQSYY--RWDSGVRDIMRLPAGALADPV----------------- Streptomyces_niveus_DSM_40088_AAF67510_NovQ ----------------MPALPMNQEFDRE----RFRVDLRATAAAIGAPVTPRVTDTVLETFRDNF-AQ--GATLWKTTS--QPGDQLSYRF-FSRLKMDTVGRAVDAGLL-DGT-HPTVPIVEDWSDLYGGTPVQSADFDAGRGMAKTWLYF--GGLRPAEDILSVPALPAPVQARLKDFLGL-GLA--HVRFAAVDWRHRSANVYFRG-------QGPLDTAQFARVHALSGGTPPA--------ADVVAEVLAYV-PEDYCVAITLDLHTGAIDRVCFYA------LKVPKDARP----------RV--PARI---ATFLEVA---PSHDPE--ECNVIGWSFGRSGD-YVKAERSYTGNMTEILSGWNCFFHGEEGRDHDLRALQDTGSITGGAR- Streptomyces_roseochromogenes_oscitans_DS_12.976_AAN65239_CloQ ----------------MPALPIDQEFDCE----RFRADIRATAAAIGAPIAHRLTDTVLEAFRDNF-AQ--GATLWKTTS--QPGDQLSYRF-FSRLKMDTVSRAIDAGLL--DAAHPTLAVVDAWSSLYGGAPVQSGDFDAGRGMAKTWLYF--GGLRPAEDILTVPALPASVQARLKDFLAL-GLA--HVRFAAVDWRHHSANVYFRG-------KGPLDTVQFARIHALSGSTPPA--------AHVVEEVLAYM-PEDYCVAITLDLHSGDIERVCFYA------LKVPKNALP----------RI--PTRI---ARFLEVA---PSHDVE--ECNVIGWSFGRSGD-YVKAERSYTGNMAEILAGWNCFFHGEEGRDHDLRALHQHTESTMGGAR Streptomyces_sp._303MFCol52_2521683528 ---------------------MSGTADIE----RLYPVVEEAAGLLDIACPPERMRPVLTAFRDAL-AD---PVVFNAVTKGGRIADLSFDFTLPASAGDPYAIAVAHGLA-EETDHPIRTLFSDLRARLP-VQGYGVDYGVNGGFNKTYAFFPLGDLQALAELAALPSMPPALSEHLALFTEH-GLGH-KVSALAIDYARRTWNVYFNG-----LPADFVRRTAVLPMLRAFGLPEPS--------EQ----LLDFI-ETSSALYPTFGWDSSKIERISFST------RTTNPVALPA---------RI--EPKL---EKFARSA---PYAYEGE-RVLVYAGALSPSEE-YYKLATYY--RMSAAAHDRVRAAN------------------------ Streptomyces_sp._303MFCol52_2521683684 ---------------------MSKATEVD----RVYAAVEKAAALAGTTCAGDKVRPVLTGHQDLL-DE--AVIVFSMTASGSHSGGLDLSMTVPAEHVDPYSFALSEGLI-EPTDHPVGSVISDFQERFP-IGMYGIDVDVAGGFKKAYAAFPSNDLRELKQLFDLPSMPSAAAENAELFARY-GLD--RVTGVSVDYKRHELNLYCDR-----ATTEPLDPDYVQSMLRDMGLKEAS--------EQ----GLEFA-KKTFAIYPTLNWDSSEIVRICFAV------ITTDPATTPT---------RS--EPELGQMWEYANTA---PYAYVGEQRALVYGLALSPEKE-YYKLGAYY--QISDYQRKLVKAFDALPE-------------------- Streptomyces_sp._CNB632_2561470561 ---------------------MPEATKLE----TVFSAVEETARLVDAPCSREKVWPALETFGRWL-DD--AHIIFSMGTGRKYRGELAFDFTVPAEAGDPYAAAVAGGLL-EKVDHPVTGLFSEIGDRFP-VDAYAVDYGVRGGFKKACVFFPLAKPQSMKALAELPSIPPALAAHADYFAAA-GLDG-KVSCIGIDYGSRTWNLYISG-----LTPDYTRPDAIVATLGEMGLSKPS--------ED----MLEFI-STSFAMYPTFGWDTTRIERMCFST------RTSDPNLLPA---------RI--EPDV---AKFARDM---PTVHGGE-PSYVYAGTVARGEE-FFKLASYY--QMSSQVSERVRPAD------------------------ Streptomyces_sp._CNB632_2561472124 ---------------------MSATAEMD----ELYAVIEQSARTLGVPCAPEKVRPVLAAYEDAF-GHAATVVAFRVATSVRHAGELDCRFTTHPDERDPYATALAAGLA-RRTDHPVGAVLAQLQGRCH-VDSHGIDFGVVGGFKKVYAFFTPDDLQEVAKFADLPAMPRALAEHTGFFARH-GLAD-RVGVVGVDYGHRTLNVYFND-----VPAQLFEPGTVSATLRELGMARPS--------AQ----MLKLG-REAFGLYVTLGWDSPRIERICYAV------TTADLAALPV---------PV--EPEI---ERFVRGV---PADDGD--RKFVYGVAVAPEGE-YYKLESHY--RWKPGTMDFI---------------------------- Streptomyces_sp._CNB632_2561473002 ---------------------MSAEPAIE----RLCVAAEDAAGIVGLECPREKMTAVLTAFPNVV-TD--STVVFNVVNKGGRVGDMSFDFTVPLAAGDPYERALAHGLA-EETNHPVRGMFADMLTTLP-VDCYGVDYGVNGGFNKAYAVFPMGRLQELHKLAAVPAMADTLSKWRGLLADY-GLDG-KVSTVAVDHANRTWNVYFNG-----LSAEQFERPTLQAMIRDFGLPEPS--------AQ----LLDFA-ETSSALYPTFSWDSPEIERVSFST------RTTDPNALPA---------HV--EPKL---GALAANA---PYTYDGD-RRLVFAGALTTGGE-YYKLATYY--QMATAAHDRVRRGG------------------------ Streptomyces_sp._CNB632_2561473004 ---------------------MSESAEFA----HLYQAIEKSARLLEVPYAHDKVQAVLTAYKDAI-PK--TPIAFRMGTGARYSSDVDWRFTIPRDHEDPYTVAVTHGLL-EPSDHPVFPLYGEVLQRCG-IHCYGVDFGVAGGLKKLYINFRPDDMEPLSAFLDIPSMPPSVAENYDFFVQH-GMGGPQMPMFAIDYRYRTANLYFGG-----LTAEPLAPDTVRSIFSRLQLPEPS--------ER----LLKLS-GRAMGAYATLSWDSSKIERFAFTI------PAGDVSELPV---------PM--EPEI---QKFLGDV---KGEVADDSHRFVYYVAMSSTGEELYKFQSYY--RYEPWLRELMTLNGQGRGS------------------- Streptomyces_sp._CNB632_2561473755 ---------------------MSGAKDVE----RVYSAMEEAAGLLNVPVARDKIWPVLTAYQDAL-AD--AVIVFSMAGG-RRSTELDFSISVPTDHGDPFTTALERGLT-EKENHPVDNLLAELRDGFP-LGMYAIDGMVTTGFKKAYASFPTNEPQPLTALLDLPSMPESARANAELFARY-GLD--KVQMVSVDYPKRQVNLYFSE-----LKADHLTPEQVKATASEMGLVEPT--------DM----ALDFA-TGSFAVYPTLGYDSDVVDRITYAV------ISVDPTLAPT---------TS--EPEKTQITTYANSA---PYAYAGENRTLVYGFTLTSKEE-YYKLGSYY--QITDLQRTLVKAFEALD--------------------- Streptomyces_sp._CNB632_2561476030 ---------------------MSGTAELE----KVYSAIEESARLVGVACSRDNVWPILAAFGESI-ED--ALMVFSLQTGGRHAGELDYSFTAPPGIGDPYPRALSHGFV-SETDHPVGSVLSDLQGRWA-IREHFVDCGVTGGFKKLYAHFP-QDLQPAARLAEIPSVPRAVADNAGLFARY-GLD--RVAMVGVDYQRRTMNLYFQF-----TPDGRPEPGALRSMLREIGLYEAD--------EG----MLEFA-SRSMRANITFSWDSARIVRVAFAPPPG---KGLDPAAVPA---------PI--EPHI---ARFATSA---PYAYAGE-RMNLFGVKWFPDGE-FIDVCAYY--QLSAGYEPVRLMETHKDQT------------------- Streptomyces_sp._CNB632_2561476124 --------------------MLAEKTDVE----KVYASLEEAARLVGASCARDKVWPVLREFGAVL-GE--DLVVLGVQSGRRNEGELDFSFRVPAAIGNPYPYALAKGFA-TGTDHPVGALLSDVAARVP-VGEYFVDGGVAGGFKKLYAHFP-QELQPLTALAGLPSMPDAVGENADLFARF-GLD--TVAMVGVNYRETKMNLYFQF-----TPESRPEPKAVGAMLREMGMPEPD--------EP----VLRYV-RGAMRANITLTWDSARISRVALAPPPS---SGLEPSDVPV---------PL--EPRM---ERFLRHA---PYAYEGE-RVRLIAFKWVPGEE-FIEANSYY--RLSPLLKQLTRPADMSPEGRRENHAQ------------ Streptomyces_sp._CNB632_2561476125 --------------------MPSSSAD------SLYAAIRKTARLVDVPCDHAKVRPLVDAFADLL-PQ--AAILFRVATDARHAGELNCHLMMLPSSVDPHARARSAGLL-PRTDHPVGTLLSDIEERFP-VGGYGLDFGLVGGFQKAWSCFPGDEMQSLPELARLPSMPPSVAGNMGFFRRY-GLAE-KITLIGMDYAHRTMNVYFGE------VEDCLTPEAVRSMLRDLDMPEPS--------EQ----MLTFT-RQAFGFYATLSWDSPKIERFCYSA------ITPDPLALLE---------RV--DPKI---EHFLREI---PYGADD--PKAVYVATSPGDGE-YYKVQAYY--QWRPRLVNHMHTQAPPTTGQPD---------------- Streptomyces_sp._CNH099_2516097927 ---------------------MPEATKLE----TVFSAVEETARLVDAPCSREKVWPALETFGRWF-DD--AHIIFSMGTGHKYRGELAFDFTVPPEAGDPYAAAVAGGLL-EKVDHPVTGLFSEIGDRFP-VDAYAVDYGVRGGFKKACVFFPLARPQSMKALAELPSIPPALAAHAEYFAAA-GLDG-KVSCIGIDYGSRTWNLYISG-----LTPDYTRPDAIVATLGEMGLSKPS--------EH----MLEFI-STSFAMYPTFGWDTTRIERMCFST------RTSDPNLLPA---------RI--EPDV---AKFARDM---PTVHGGE-PSYVYAGTVARGEE-FFKLASYY--QMSSKVSERVRPAD------------------------ Streptomyces_sp._CNH099_2516099186 ---------------------MSATAEMD----ELYAVIEQSARTLGVPCAPEKVRPVLAAYEDAF-GHAATVVAFRVATSIRHAGELDCRFTTHPDERDPYATALAAGLA-GRTDHPVGAVLAQLQGRCH-VDSHGIDFGVVGGFKKVYAFFTPDDLQEVAKFADLPAMPRALAEHTGFFARH-GLAD-RVGVVGVDYGHRTLNVYFND-----VPAQLFEPGTITATLRELGMARPS--------EQ----MLKLG-REAFGLYVTLGWDSPRIERICYAV------TTADLAALPV---------PV--EPEI---ERFVRGV---PADDGD--RKFVYGVAVAPEGE-YYKLESHY--RWKPGTMDFI---------------------------- Streptomyces_sp._CNH099_2516101115 ---------------------MSGAKDVE----RVYSAMEEAAGLLNVPVARDKIWPVLTAYQDAL-AD--AVIVFSMAGG-RRSTELDFSISVPTDHGDPFTTALERGLT-EKENHPVDNLLAELRDGFP-LGMYAIDGMVTTGFKKAYASFPTNEPQPLTALLDLPSMPESARANAELFARY-GLD--KVQMVSVDYPKRQVNLYFSD-----LNADHLTPEEVKSTASEMGLVEPT--------DM----ALDFA-TGSFAVYPTLGYDSDVVDRITYAV------ISVDPTLAPT---------TS--EPEKTQITTYANSA---PYAYAGENRTLVYGFTLTSKEE-YYKLGSYY--QITDLQRTLVKAFEALD--------------------- Streptomyces_sp._CNH099_2516101746 ---------------------MSESAEFA----HLYQAIEKSARLLEVPYAQDKVHAVLTAYEDAI-PK--TPIAFRMGTGARYSSDVDWRFTIPKEHEDPYTVAVAHGLL-EPSDHPVFPLYGEVLQRCG-IHCYGVDFGVAGGLKKLYINFRPDDMEPLSAFLDIPSMPPSVAENYDFFVQH-GMGGPQMPMFAIDYRYRTANLYFGG-----LTAEPLAPDTVRSIFSRLQLPEPS--------ER----LLKLS-GRAMGAYATLSWDSSKIERFAFTI------PAGDVSELPV---------PM--EPEI---QKFLEDV---KGEVADDSNRFVYYVAMSSTGEELYKFQSYY--RYEPWLKELMTLNGQGRGS------------------- Streptomyces_sp._CNH099_2516101748 ---------------------MSAEPAIE----RLCVAAEDAAGIVGLECPREKMTAVLTAFPNVV-TD--STVVFNVVNKGGRVGDMSFDFTVPLAAGDPYERALAHGLA-EKTNHPVRGMFADMLTTLP-VDCYGVDYGVNGGFNKAYAVFPMGRLQELDKLAAVPAMADTLSKWMGQLVDY-GLDG-RVSTVAVDHANRTWNVYFNG-----LSAEHFERPTLQAMIRDFGLPEPS--------AQ----LLDFA-ETSSALYPTFSWDSPEIERVSFST------RTTDPNALPA---------HV--EPKL---GALAANA---PYTYDGD-RRLVFAGALTTGGE-YYKLATYY--QMATAAHDRVRRGS------------------------ Streptomyces_sp._CNH099_2516104298 ---------------------MSGTAELE----KVYSAIEESARLVGVACSRDNVWPILTAFGESI-ED--ALMVFSLQTGGRHAGELDYSFTAPPGIGDPYPRALSYGFV-TETDHPVGSVLSDLQGRWA-IREHFVDCGVTGGFKKLYAHFP-QDLQPAARLAEIPSVPRAVADNAGLFARY-GLD--RVAMVGVDYQRRTMNLYFQF-----TPDGRPEPGALRSMLREIGLHEAD--------EG----MLEFA-SRSMRANITFSWDTSRIVRVAFAPPPG---KGLDPAAVPA---------PI--EPHI---ARFATSA---PYAYAGE-RMNLFGVKWFPDGE-FIDVCAYY--QLSAGYEPVRLMETHKNPT------------------- Streptomyces_sp._CNH099_2516104521 --------------------MPSSSAD------SLYAAIQKTAGLVDVPCEHAKVRPLVDAFADLL-PQ--AAILFRVATDARHAGEMNCHMMMLPSSVDPHARAQSAGLL-PRTDHPVGTLLSDIEERFP-VGSYGLDFGLVGGFQKAWSCFPGDEMQSLPELARLPSMPPSVAGNMGFFRRY-GLAE-KITLIGMDYAHRTMNVYFGE-----V-DDCLTPDAVRSMLRDLDMPEPS--------EQ----MLAFA-RQAFGFYATLSWDSPKIERFCYSA------ITPDPLALLE---------RV--DPKI---EHFLREI---PYGADD--PKAVYVATSPGEGE-YYKVQAYY--QWRPRLVNHMHTEAPPTTGQPG---------------- Streptomyces_sp._CNH099_2516104522 --------------------MLAEKTDVE----KVYASLEEAARLVGASCARDKVWPVLREFGAVL-GD--DLVVLGVQSGRRNEGELDFSFRVPAAIGDPYPYALAKGFV-TGTDHPVGALLSDVAARVP-VGEYFVDGGVAGGFKKLYAHFP-QELQPLTALAGLPSMPDAVGENADLFARF-GLD--TVAMVGVNYRETKMNLYFQF-----TPESRPEPKALGAMLREMGMPEPA--------EP----VLRYV-RGAMRANITLTWDSARVSRVALAPPPS---SGLEPSDVPV---------PL--EPHM---ERFLRHA---PYAYEGE-RVRLIAFKWVPGEE-FIEANSYY--QLSPLLKQLTRPADMSPEGRRENHAQ------------ Streptomyces_sp._CNH189_2515835839 ---------------------VSGETDAE----ELCSAIEETARLVGAPCSREKIWPILTEYRSGF-AE--GGVVFSAQAGENHAGELDYGLAVPPRIDDPYAHALAHGFV-TETDHPVAALLSDIRERCA-VTEHFADCGVVGGFRKLYAHFP-RDLQKVSEIADIPSMPRAVAENVGLFTRY-GLE--NVVMVGVNYKNKTVSLYFQF-----TAEGRPRPSAIRSMLGDIGMTEPN--------ER----MLDFA-SNSFRANITLSWDSPKILRVAFAPPPG---AGLNLSTVPI---------PT--GPHL---EDFVTRA---PRAYDGE-RMNLFAVKWTQDKE-FLEVCSYY--QLPAGYEPIRQMEIHKEQG------------------- Streptomyces_sp._CNH287_2524586714 ---------------------MYGGTEVE----EVYSALEKSAGLVGVPCNRDKVWPALSTYQDAL-GE--AVIVFSVATDERHAGELDYTITVPTGGADPYALALAKGLT-PETDHPVGTLLAGVQERCP-VAGYAVDCGVVGGFKKIYSFFPQDDLQGLAKLAEIPSMPRALAENAALFARH-GLDH-KVTMLGIDYQRESVNLYFGK-----LPEECLQPDSIRAILRDIGLPEPT--------EP----MLEFA-RKSFAIYVTLSWDAAKVERICFAVPPGRDLITLDPSALPA---------RI--APEI---EHFARNS---PYAYPGD-RMLVYGVTWSPEEE-YYKLGSYY--QLPVQTRKLLVAFDSVKDQE------------------ Streptomyces_sp._CNH287_2524588539 ---------------------MSQTAQPA----GLYPAIEEAARLLDVPCSREKVEPVLTAYGDTL-DQ--AVIAFRVATGARHAGELDCRFTMLPKDVDPYALALSRGLT-AKTDHPVGSLLADLQARFP-VDSHGIDFGVVGGFKKSWSFFPPDDLQQLAQLAQLPAMPRSLAANLDFFTRH-DLHD-KASLIGIDYRHKTVNIYFGQ-----PPAACFVPENVTSMLHELGLPAPS--------EQ----MLRLG-EQAFGIYVTLSWDSLKVERLCLAV------MTPDPTALPV---------EI--EPRI---EQFIKSA---PHTDPEEDRRFVYAVTASPAGE-YFKLQSYY--QWRPRMLNLMLLD------------------------- Streptomyces_sp._CNP082_2527270384 ---------------------MPVSKNAE----AVYSAIEDAAGLLDIPCSREKVMSVLAAFGDGVSEE--SVVVLAMAGGERHGGDIDYNFTVPTEVGDPYEIAVANGWI-EPTDHPIANLLPEIVESSP-VTFYGVESGVVDGFKKTYIFFPLDNLGKLSTLASLPSMPSSVAEHAATFGLN-GMDN-RISIIGIDYIRKTVNVYFMA--------GPLEEKSCLSLLEETNLPAPN--------PQ----LLEFI-PNSFSIYPTFTYDSPDIHRICFSS------VSPDDTAYPT---------TL--HDEI---ARFAKNA---PYEYGGA-RVLVYGATVSRTEE-YHKLGVYF--RRPAAFWDNLPLAATFEKLAAAHRGA------------ Streptomyces_sp._CNP082_2527270866 ---------------------MTGAG-ME----GLYAAIEETSGLLDISPSRDKVWPILSAYD--L-EK--VVVAFRVTT--RGSRDLDCRFTALPADVNPYRYAVSKGIA-EATDHPVGTLLDDVQANIP-VTAHGVDFGVSEGFRKTWTFLPGNDLQKLSKVAALPSMPPSLAENLDFYARY-GLDD-KNSMIGIDYPSRTVNVYFLQ-----FPGECREPETVRAMLRDLGLPEPS--------SQ----LLTLA-RQAIGIYTTLTWDSPKIQRITFAT------RVADARALPG---------RIAVEADV---EKFAMNV---PHTYPGP-VQGMYNVASYSGGE-YFKLQTYH--QLSEGSLEARVLLGPAG--------------------- Streptomyces_sp._CNP082_2527270867 --------------------------------------------MVGAPFSRDQVWPILSAFSGGFSDT--GGVIISLQAG-TQVSEMEYSAQVSPGIGDPYAHALASRIL-TPTDHPVSTVLSEIVALVP-TSEHYIDCGITGGFKKIYANFP-HAPQTVSALAGLPSIPRAVGENAEFFARY-GLE--DVALIGVDYKNRTINLYFQAPA---ATAGDLGPKTVSAMLRETGMSTPS--------EQ----MTAYA-GRAYRIYATLGWDTQEILRIAFAPQPH---RSIDLAELPA---------RL--EPRI---RQFMRAT---PHKYPGA-LINATAAKWSPVYE-VLDLAAYY--QVSALHLKAIEAEEGQTS-------------------- Streptomyces_sp._CNQ329_2528489393 ---------------------MSAQADIE----TVHSAIEEAAGLLNLTCSPGTVRPILEAFGPFE-----GGVIFSASAGEGHAGDLDLTIQVPRAIDDPYTHALTHGFV-PQTDHPVSTLLSDLKERVS-VDECLIDFGVIAGFNKIYVHFP-RDLQTVAQLAALPSMPRALADNAELFARH-GLD--KVAMLSIDYHKRTINPFFTF-------PNGLEAKTISSLLHEFGVLEPD--------EE----LVESS-SKIFRAYPTLGWESSKIDRISFA-------RSLDLPTIRP---------RV--EPEI---VRFVTGT---PYTYDGE-RFSISIVKWSPDDT-WFNVGSYF--QFGPLQREVLGKVLR----------------------- Streptomyces_sp._CNQ329_2528491298 ---------------------MPESKNAE----AVYSAIEESAGLLDIPCSRQKVMSVLSAFGDGVSEE--SVIVMAMAGGERHGGDIDYNFTVPTEVGDPYEIAVANGWI-EALDHPIANLLPEIVESSP-VTFYGVEAGVVEGFKKTYIFFPLDNLGKLSTLASLPSMPRSVAEHARTFDGLNGMGD-RISIIGIDYIKRTVNVYFMA--------GTLGEKSVLSLLEDTNLPAPT--------PD----FLEFV-QNSFSIYPTFTYESSDIHRICFSS------VSPDDTAYPT---------TL--HEEI---ARFTKNA---PYEYDGA-RVLVYGATISRREE-YHKLGVYF--RRPPAFWDNLPLAATFEKLAAAHRGA------------ Streptomyces_sp._CNQ329_2528491789 ---------------------MTGTG-ME----GLYAAIEEASGLLDISPSRDKVWPILSAYD--L-EK--VVVAFRVTT--RASRDLDCRFTALPADVNPYRYAVSKGIA-EATDHPVGTLLDDVQANIP-VIAHGVDFGVTAGFRKTWTFLPGNDLQKLSKVAALPSMPPSLAENFDFYARY-GLDD-KNSMIGIDYPSRTVNVYFLQ-----FSDECRRPETVRAMLSDLGLPEPS--------EQ----MLALA-NQAVGIYTTLTWDSPKIQRITFAT------LVPDAQALPE---------RIQVEPNV---EKFARNV---PHTYPGP-VQGLYNVASYSGGE-YFKLQTYH--QLAEGSLEARVLLGTAGAGN------------------ Streptomyces_sp._CNQ329_2528491790 -MIGSHRIHRKLVGIDCLECLVSEVFEAE----GLYSAIEESARLVDAPFSRDKVWPILSAFAGGLSDA--GGVIFSLQAG-KQVPEMEYSVQISSGIADPYAHALAGGIL-TETDHPVSTVLSEIVSLAP-TSEHYIDCGIVGGFKKIYANFP-HDQQKVSRLADLPSMPRAVGENAEFFSRY-GLD--NVALIGVDYRNKTINLYFQAPA---AIAGNLDPKTVSAMLRETGMSTPS--------EE----MVAYA-GRAYRIYATLGWDAREIRRIAFAPQPR---RSIDLAELPA---------RL--EPRI---EQFMRAT---PHKYAGA-LVNATAAKWSHEHE-VLDLAAYY--QISVVHMKAIQAEEGQSS-------------------- 'Streptomyces sp. CNQ509 AA958_12625 ' --------------------MLADKTEVE----EVYSALEESARLVGAVCVRDKAWPVLDAFGAVV-GE--DLVVLGVQSGKRNAAELDFSFRVPGEIGNPYPYALEKGFV-GETDHPVGTLLSDVGARFP-VQEYYVDAGVVGGFKKLYAHFP-LALQPLAALTDIPSMPEAVAENAGLFARY-GLD--KVAMVGVNYRANTMNLYFQF-----APDNRPEPGALASMLREMGMPEPT--------EA----VLRYV-SAAMRANITLGWDSAHIFRVALAPPPS---AGFEPAEIPA---------PM--EPHM---ERFVREA---PFAYEGE-RVNLIAVKWVPEEQ-FVEANSYY--QLSPMLKKLTRGD------------------------- 'Streptomyces sp. CNQ509 AA958_12635 ' ---------------------MSSPAE------NLYAAIEKTAGLVDVPCAREKVWPILSAFEELL-PQ--AAILFRVATDARHAGEINCHMMMLPSTIDPHALAQANGLL-PRKDHPIDSLLGDIEAGFP-IGSYGVDFGLVGGFQKAWSCFPGEQMQSLPKLAALPSMPPSVAGNMDFFERY-GLAE-KITLIGMDYGHRTMNVYFGE------VDDCLTPAAVRSMLSDIGMPEPS--------EH----LLTFA-QQAFGFYTTLSWDSPDIERFCYSA------ITPDPLAILD---------RV--EPKI---EHFLREI---PYGADN--PKAVYVATSPGDGE-YCKVQSYY--QWRPRLVNHMHTTAPPASG------------------- 'Streptomyces sp. CNQ509 AA958_12645' ---------------------MSTNPGIE----RLCAAAEEAAGLVGVDCPPEKMTALLTAFPNVV-TD--STVVFNAVNKGGSIRDLSFDFTVPLAEGNPYERALEHGLA-EETDHPVRGMFADLLTALP-VDCYGVDYGVNSGFNKSYAVFPMGRLQELGPLASVPAMSTALSRWMDVLVEY-GLDG-KVSTVAIDHANRTWNVYFNG-----LSPEHFERATVQAMLRDFGLPEPS--------GQ----LLDFA-ATSSALYPTFGWDAAEIERVSFST------RTTDPAALPS---------HV--EPKL---GVLAAKA---PYSYEGD-RKLVFAGALTADGE-YFKLATYY--QLATAAHDRVRRGS------------------------ 'Streptomyces sp. CNQ509 AA958_18620' ---------------------MSGANDVE----RVYSAMEEAAGLLGVPVAREKVRPVLTAYQDAL-AD--AVVVFSMAGG-RRATELDFSISVPTDHGDPFTTALQRGLT-EKTGHPVDNLLAELREGFP-LGMYAIDGMVSTGFKKTYASFPTNEPQPLDDLLDVPSMPASARANAKLFANY-GLD--KVQMVSVDYPKRQVNLYFSE-----LNTDYLQPAQVKALAAEMGLIEPS--------EL----GLEFA-KGSFAVYPTLSYDTDASDRLCLAV------ISSDPTLAPT---------TS--EPEVTQFSTYANNA---PYAYAGENRTLVYGLTLTPKEE-YYKLGSYY--QITDYQRKLVKAFEALD--------------------- 'Streptomyces sp. CNQ509 AA958_24270 ' ---------------------MSGAVELE----RVYSAIEESAHLVGVACSREKVWPLLSTFGESI-ED--ALLVLSLQTGGRHAGELDYSFTASPGLGDPYPHAVAHGFL-EPTDHPVHSLLSDLQGRWT-IREHFVDCGVTGGFKKLYAHFP-QDLQPVAKLAEVPSVSHAVADNAGLFARY-GLD--EVAMVGVDYKRQTMNLYFQF-----TPDGRPEPSALRAMLREIGLYDAD--------EG----MLEFA-SRSMRANITFRWDSSRIVRVAFAPPPG---RGLDPAAVPA---------PI--EPHI---ARFATNA---PYAYPGE-RLNLFGVKWFPDGE-FIDVCAYY--QLSAGYEPVRLMETHKR--------------------- 'Streptomyces sp. CNQ509 AA958_24325' ---------------------MSGAADVE----RVYSAMEEAARLLDITVSREKVRPALEAYHEVL-AD--AVVVFSMASG-RYATELDFSISVPAEAGDPYRVALAKGLT-PRTDHPVGRLLADTQEHCP-VSMFAFDGEITGGFKKTYAFFPTNDLQSASKLAEIPSMPDSVKENADLFARY-GLD--KVQMTSIDYKKKAVNLYFSE-----MSPDILGPDTVRSMLRDMGLKETG--------ET----GLTFA-RRSFSVYPTLNWETGRIERLCFAV------ISRDPTLAPA---------ER--AEDL---AKFSKYANNAPYAYAGEARTLVYGLTLTPREE-YYKLGSYY--QISDIQRKLLKAFDSLND-------------------- 'Streptomyces sp. CNQ509 AA958_30735' ---------------------MPEATKLE----TIYSAVEQTSRLVDAPCAREKIWPALDTFGKWLVDD--AHIIFSMGTGERYRGELAFDFTLPTEAGDPYAAAVAGGLL-EETDHAITGLFTEIRDRFP-VDAYAVDFGVVGGFRKAVTFFPLAKPQSMKALTELPSIPPGLAAHADSFAEA-GLDG-KVSAIGVDYRSRSWNLYVSG-----LTPEYTRPDALIPTLRDMGLPEPS--------EH----MLEFI-GTSYAMYPTFGWDTTRIERMCFST------RTSDPDLLPS---------RI--APEV---GRFARDM---PTVHGGE-PSYVYAGTVARGEE-FFKLASYY--QMSSQVSDRVRPAD------------------------ Streptomyces_sp._CNQ525_2562118558 ---------------------MPEATELE----TIYSAVEETARLVDAPCSRDRVWPALDTFGKWL-DD--AHIIFSMGTGNRYRGELAFDFSLPKAAGDPYAAALAGGLL-DKVDHPIAGLLPEIRDRFT-VDAYGVDFGIVGGFRKAVAFFPLAEPQSMKALTELSSIPPALAEHAESFGAA-GLDG-KVSAIGVDYRSRSWNLYISG-----LTPEYTRPDAIIPTLRGMGLPEPS--------EH----MLEFI-GTSYAMYPTFGWDSTRIERMCFST------RTSDPDLLPA---------RI--EPAV---GKFAREM---PTVHKGE-PSYVYAGTVARGEE-FFKLASYY--QISSQVSDRVRPAD------------------------ Streptomyces_sp._CNQ525_2562121671 ---------------------MSATAETD----ELYSVIEQSARTLGVPCEPGTVRPVLTAYADAF-GHEAAVVAFRVATSLRHAGELDCRFTTHPEERDPYATALAAGLT-RPTDHPVGAVLAQVQGRCR-VDSHGVDFGVVGGFKKVYAFFTPDDLQDLAKFADLPAMPPALAAHADFFARH-GLAD-RVGVIGVDYHHRTLNVYFND-----VPPRLFEPDAITATLRELGMAAPS--------AH----MLKLG-REAFGLYVTAGWDAPRIERICYAV------TTPDLAALPV---------RV--EPEI---ERFVRGV---PAGDGD--RKFVYGVAVAPGGE-YYKLESHY--RWQAGTMDFI---------------------------- Streptomyces_sp._CNQ525_2562123443 ---------------------MSAQADIE----TVHSAIEEAAGLLNLTCSPGTVRPILEAFGPFE-----GGVIFSASAGEGHAGDLDLTIQVPRAIDDPYAHALKHGFV-PHTDHPVSTLLSDLKEHVS-VDECLIDFGVIAGFNKIYVHFP-RDLQGVAQLAALPSMPRALADNAEFFARH-GLD--NVAMLSIDYHKRTINPFFTF-------PKGLEAKTISSLLHEFGVVEPD--------EE----LVESS-SKIFRAYPTLGWESSKIDRISFA-------RSLDLPTIRP---------RV--EPEI---VRFVTGT---PYTYDGE-RFSISIVKWSPDDT-WFNVGSYF--QFGPIQRAVLGKVLR----------------------- Streptomyces_sp._CNQ525_2562123520 ---------------------MTDTG-ME----GLYAAIEEASGLLDVAPSRDKVWPILSAYE--L-DK--VVVAFRVTT--RGSKDLDCRFTALPADVNPYRYAVSKGIA-EATDHPVGTLLDDVQANIP-VTAHGVDFGVVEGFRKTWTFLPGNDLQKLSKVAALPSMPPSLAENLDFYARY-GLDD-KNSMIGIDYPSRTVNVYFLQ-----FPDETREPETVRAMLRDLGLPEPS--------EQ----MLTLA-KQAVGIYTTLTWDSPKIQRITFAT------LVPDAEALPG---------RIAVEPSV---EKFARNV---PHTYPGP-VQGLYNVASYSGGE-YFKLQTYH--QLAEGSLEARVLLGAAGAGS------------------ Streptomyces_sp._CNQ525_2562123521 --------------------------------------------MVDAPFSRDKVWPTLSAFEGGFSDA--GGVILSLQAG-THVPEMEYSAQVSPGISDPYARALASGIL-TETDHPVSTVLAEIVSLAP-TSEHYIDCGIVGGFKKIYANFP-HDQQTVAALAGLPSMPRAVGGNAEFFARH-GLD--RVALIGVDYVNKTINLYFQVSA---ATAGNLDQKTVSAMLHETGMSEPS--------DA----MVAYA-CQAYRIYTTLSWDAQEILRIAFAPKPR---RGIDPADLPA---------RL--EPRI---EKFLRAT---PHKYPGA-LINATAAKWSPERE-VLDLAAHY--QVSAVQMKAIEAEEGQAS-------------------- Streptomyces_sp._CNQ766_2518002741_ ---------------------MPEATELE----TIYSAVEETARLVDAPCSRDRVWPALDTFGKWL-DD--AHIIFSMGTGNRYRGELAFDFSLPKAAGDPYAAALAGGLL-DKVDHPIAGLLPEIRDRFT-VDAYGVDFGIVGGFRKAVAFFPLAEPQSMKALTELSSIPPALAEHAESFGAA-GLDG-KVSAIGVDYRSRSWNLYISG-----LTPEYTRPDAIIPTLRGMGLPEPS--------EH----MLEFI-GTSYAMYPTFGWDSTRIERMCFST------RTSDPDLLPA---------RI--EPAV---GKFAREM---PTVHKGE-PSYVYAGTVARGEE-FFKLASYY--QMSSQVSDRVRPAD------------------------ Streptomyces_sp._CNQ766_2518005124 ---------------------MSATAETD----ELYSVIEQSARTLGVPCEPGTVRPVLTAYADAF-GHEAAVVAFRVATSLRHAGELDCRFTTHPEERDPYATALAAGLT-RPTDHPVGAVLAQVQGRCR-VDSHGVDFGVVGGFKKVYAFFTPDDLQDLAKFADLPAMPPALAAHADFFARH-GLAD-RVGVIGVDYHHRTLNVYFND-----VPPRLFEPDAITATLRELGMAAPS--------GH----MLKLG-REAFGLYATVGWDTPRIERICYAV------TTSDLAALPV---------RV--EPEI---ERFVRGV---PAGDGD--RKFVYGVAVAPGGE-YYKLESHY--RWRAGTMDFI---------------------------- Streptomyces_sp._CNQ766_2518006200 ---------------------MSAQADIE----TVHSAIEEAAGLLNLTCSPGTVRPILEAFGPFE-----GGVIFSASAGEGHAGDLDLTIQVPRAIDDPYTHALTHGFV-PHTDHPVSTLLSDLKKHVS-VDEYLIDFGVIAGFNKIYVHFP-RDLQGVAQLAALPSMPRALADNAELFARH-GLD--NVAMLSIDYHKRTINPFFTF-------SNGLEAKTISSLLHELGVVEPD--------EE----LVESS-SKIFRAYPTLGWESSKIDRISFA-------RSLDLPTIRP---------RV--EPEI---VRFVTGT---PYTYDGE-RFSISIVKWSPDDT-WFNVGSYF--QFGPRQREVLGKVLR----------------------- Streptomyces_sp._CNQ766_2518006639 --------------------------------------------MVDAPFSRDKVWPTLSAFEGGFSDA--GGVILSLQAG-THVPEMEYSAQVSPGISDPYARALASGIL-TETDHPVSTVLAEIVSLAP-TSEHYIDCGIVGGFKKIYANFP-HDQQTVAALAGLPSMPRAVGGNAEFFARH-GLD--RVALIGVDYVNKTINLYFQVSA---ATAGNLDQKTVSAMLHETGMSEPS--------DA----MVAYA-CQAYRIYTTLSWDAEEILRIAFAPKPR---RGIDPADLPA---------RL--EPRI---EKFLRAT---PHKYPGA-LINATAAKWSPERE-VLDLAAHY--QVSAVQMKAIEAEEGQAS-------------------- Streptomyces_sp._CNQ766_2518006640 ---------------------MTDTG-ME----GLYAAIEEASGLLDVAPSRDKVWPILSAYE--L-DK--VVVAFRVTT--RGSKDLDCRFTALPADVNPYRYAVSKGIA-EATDHPVGTLLDDVQANIP-VTAHGVDFGVVEGFRKTWTFLPGNDLQKLSKVAALPSMPPSLAENLDFYARY-GLDD-KNSMIGIDYPSRTVNVYFLQ-----FPDETREPETVRAMLRDLGLPEPS--------EQ----MLTLA-KQAVGIYTTLTWDSPKIQRITFAT------LVPDAEALPG---------RIAVEPSV---EKFARNV---PHTYPGP-VQGLYNVASYSGGE-YFKLQTYH--QLAEGSLEARVLLGAAGAGS------------------ Streptomyces_sp._CNQ865_2524593636_ ---------------------MSATAETD----ELYSVIEQSARTLGVPCEPGTVRPVLTAYADAF-GHEAAVVAFRVATSLRHAGELDCRFTTHPEERDPYATALAAGLT-RPTDHPVGAVLAQVQGRCR-VDSHGVDFGVVGGFKKVYAFFTPDDLQDLAKFADLPAMPPALAAHADFFARH-GLAD-RVGVIGVDYHHRTLNVYFND-----VPPRLFEPDAITATLRELGMAAPS--------GH----MLKLG-REAFGLYVTVGWDTPRIERICYAV------TTPDLAALPV---------RV--EPEI---ERFVRGV---PAGDGD--RKFVYGVAVAPGGE-YYKLESHY--RWRAGTMDFI---------------------------- Streptomyces_sp._CNQ865_2524596589 ---------------------MPEATELE----TIYSAVEETARLVDAPCSRDRVWPALDTFGKWL-DD--AHIIFSMGTGNRYRGELAFDFSLPKAAGDPYAAALAGGLL-DKVDHPIAGLLPEIRDRFT-VDAYGVDFGIVGGFRKAVAFFPLAEPQSMKALTELSSIPPALAEHAESFGAA-GLDG-KVSAIGVDYRSRSWNLYISG-----LTPEYTRPDAIIPTLRGMGLPEPS--------EH----MLEFI-GTSYAMYPTFGWDSTRIERMCFST------RTSDPDLLPA---------RI--EPAV---GKFAREM---PTVHKGE-PSYVYAGTVARGEE-FFKLASYY--QMSSQVSDRVRPAD------------------------ Streptomyces_sp._CNQ865_2524600624 ---------------------MSAQADIE----TVHSAIEEAAGLLNLTCSPGTVRPILEAFGPFE-----GGVIFSASAGEGHAGDLDLTIQVPRAIDDPYTHALTHGFV-PHTDHPVSTLLSDLKKHVS-VDEYLIDFGVIAGFNKIYVHFP-RDLQGVAQLAALPSMPRALADNAELFARH-GLD--NVAMLSIDYHKRTINPFFTF-------SNGLEAKTISSLLHELGVVEPD--------EE----LVESS-SKIFRAYPTLGWESSKIDRISFA-------RSLDLPTIRP---------RV--EPEI---VRFVTGT---PYTYDGE-RFSISIVKWSPDDT-WFNVGSYF--QFGPRQREVLGKVLR----------------------- Streptomyces_sp._CNQ865_2524600745 ---------------------MTDTG-ME----GLYAAIEEASGLLDVAPSRDKVWPILSAYE--L-DK--VVVAFRVTT--RGSKDLDCRFTALPADVNPYRYAVSKGIA-EATDHPVGTLLDDVQANIP-VTAHGVDFGVVEGFRKTWTFLPGNDLQKLSKVAALPSMPPSLAENLDFYARY-GLDD-KNSMIGIDYPSRTVNVYFLQ-----FPDETREPETVRAMLRDLGLPEPS--------EQ----MLTLA-KQAVGIYTTLTWDSPKIQRITFAT------LVPDAEALPG---------RIAVEPSV---EKFARNV---PHTYPGP-VQGLYNVASYSGGE-YFKLQTYH--QLAEGSLEARVLLGAAGAGS------------------ Streptomyces_sp._CNQ865_2524600746_ --------------------------------------------MVDAPFSRDKVWPTLSAFEGGFSDA--GGVILSLQAG-THVPEMEYSAQVSPGISDPYARALASGIL-TETDHPVSTVLAEIVSLAP-TSEHYIDCGIVGGFKKIYANFP-HDQQTVAALAGLPSMPRAVGGNAEFFARH-GLD--RVALIGVDYVNKTINLYFQVSA---ATAGNLDQKTVSAMLHETGMSEPS--------DA----MVAYA-CQAYRIYTTLSWDAEEILRIAFAPKPR---RGIDPADLPA---------RL--EPRI---EKFLRAT---PHKYPGA-LINATAAKWSPERE-VLDLAAHY--QVSAVQMKAIEAEEGQAS-------------------- Streptomyces_sp._CNS335_2518010821 ---------------------MSATAETD----ELYSVIEQSARTLGVPCEPGTVRPVLTAYADAF-GHEAAVVAFRVATSLRHAGELDCRFTTHPEERDPYATALAAGLT-RPTDHPVGAVLAQVQGRCR-VDSHGVDFGVVGGFKKVYAFFTPDDLQDLAKFADLPAMPPALAAHADFFARH-GLAD-RVGVIGVDYHHRTLNVYFND-----VPPRLFEPDAITATLRELGMAAPS--------GH----MLKLG-REAFGLYVTVGWDTPRIERICYAV------TTPDLAALPV---------RV--EPEI---ERFVRGV---PAGDGD--RKFVYGVAVAPGGE-YYKLESHY--RWRAGTMDFI---------------------------- Streptomyces_sp._CNS335_2518010999 ---------------------MPEATELE----TIYSAVEETARLVDAPCSRDRVWPALDTFGKWL-DD--AHIIFSMGTGNRYRGELAFDFSLPKAAGDPYAAALAGGLL-DKVDHPIAGLLPEIRDRFT-VDAYGVDFGIVGGFRKAVAFFPLAEPQSMKALTELSSIPPALAEHAESFGAA-GLDG-KVSAIGVDYRSRSWNLYISG-----LTPEYTRPDAIIPTLRGMGLPEPS--------EH----MLEFI-GTSYAMYPTFGWDSTRIERMCFST------RTSDPDLLPA---------RI--EPAV---GKFAREM---PTVHKGE-PSYVYAGTVARGEE-FFKLASYY--QMSSQVSDRVRPAD------------------------ Streptomyces_sp._CNS335_2518013585 ---------------------MSAQADIE----TVHSAIEEAAGLLNLTCSPGTVRPILEAFGPFE-----GGVIFSASAGEGHAGDLDLTIQVPRAIDDPYTHALTHGFV-PHTDHPVSTLLSDLKEHVS-VDEYLIDFGVIAGFNKIYVHFP-RDLQGVAQLAALPSMPRALADNAELFARH-GLD--NVAMLSIDYHKRTINPFFTF-------SNGLEAKTISSLLHELGVVEPD--------EE----LVESS-SKIFRAYPTLGWESSKIDRISFA-------RSLDLPTIRP---------RV--EPEI---VRFVTGT---PYTYDGE-RFSISIVKWSPDDT-WFNVGSYF--QFGPRQREVLGKVLR----------------------- Streptomyces_sp._CNS335_2518013945 ---------------------MTDTG-ME----GLYAAIEEASGLLDVAPSRDKVWPILSAYE--L-DK--VVVAFRVTT--RGSKDLDCRFTALPADVNPYRYAVSKGIA-EATDHPVGTLLDDVQANIP-VTAHGVDFGVVEGFRKTWTFLPGNDLQKLSKVAALPSMPPSLAENLDFYARY-GLDD-KNSMIGIDYPSRTVNVYFLQ-----FPDETREPETVRAMLRDLGLPEPS--------EQ----MLTLA-KQAVGIYTTLTWDSPKIQRITFAT------LVPDAEALPG---------RIAVEPSV---EKFARNV---PHTYPGP-VQGLYNVASYSGGE-YFKLQTYH--QLAEGSLEARVLLGAAGAGS------------------ Streptomyces_sp._CNS335_2518014051 -----------------------------------YSAIEESARMVDAPFSRDKVWPTLSAFEGGFSDA--GGVILSLQAG-THVPEMEYSAQVSPGISDPYARALASGIL-TETDHPVSTVLAEIVSLAP-TSEHYIDCGIVGGFKKIYANFP-HDQQTVAALAGLPSMPRAVGGNAEFFARH-GLD--RVALIGVDYVNKTINLYFQVSA---ATAGNLDQKTVSAMLHETGMSEPS--------DA----MVAYA-CQAYRIYTTLSWDAEEILRIAFAPKPR---RGIDPADLPA---------RL--EPRI---EKFLRAT---PHKYPGA-LINATAAKWSPERE-VLDLAAHY--QVSAVQMKAIEAEEGQAS-------------------- Streptomyces_sp._CNS654_2562084974_ ---------------MPQPAELTEPAGSA----ELYSAIEETTRVVGAPCRRDTVGPILTAYEDVI-AQ--SVISFRVQTGTSDAGDLDCRFTLLPKDIDPYAVALSNGLT-PNTDHPVCSLLEEVHRKFP-VDCYGIDFGAVGGFKKAWSFFRPDSLQSATELAALPSMPTGVSENLGLFDRY-GMTD-TVSVVGFDYAKRSVNLYFTG-----ASAESFEPRGIQAILRECGLPEPS--------EE----LLRFG-EQAFAIYVTLSWDSPKIERVTYSV------NTPDPMALPV---------RI--DPRI---EQLVKDA---PIGSAG--HRYVYGVTATPKGE-YHKIQKYY--QWQTRVEKMLAADAG----------------------- Streptomyces_sp._CNT371_2516104881 ---------------------MSVTAETD----ELYSVIEQSARTLGVPCEPGTVRPVLAAYADAF-GHEAAVVAFRVATSLRHAGELDCRFTTHPEERDPYATALAAGLT-RPADHPVGAVLAQVQGRCR-VDSHGVDFGVVGGFKKVYAFFTPDDLQDLAKFADLPAMPPALAAHADFFARH-GLAD-RVGVIGVDYHHRTLNVYFND-----VPPRLFEPDAVTATLRELGMAAPS--------AH----MLKLG-REAFGLYVTVGWDAPRIERICYAV------TTPDLSALPV---------RV--EPEI---ERFVRGV---PAGDGD--RKFVYGVAVAPEGE-YYKLESHY--RWRAGTMDFI---------------------------- Streptomyces_sp._CNT371_2516108106 ---------------------MPEATELE----TIYSAVEETARLVDAPCSRDKVWPALDTFGKWL-DD--AHIIFSMGTGNRYRGELAFDFSLPKAAGDPYAAALAGGLL-DKVDHPIAGLLPEIRDSFT-VDAYGVDFGIVGGFRKAVAFFPLAEPQSMKALTELPSIPPALAAHAESFGAA-GLDG-KVSAIGVDYRSRSWNLYISG-----LTPEYTRPDAIIPTLRGMGLPEPS--------EH----MLEFI-GTSYAMYPTFGWDSTRIERMCFST------RTSDPDLLPA---------RI--EPGV---GRFAREM---PTVHKGE-PSYVYAGTVARGEE-FFKLASYY--QMSSQVSDRVRPAD------------------------ Streptomyces_sp._CNT371_2516111586 ---------------------MSAQADVE----TVHSAIEKAAGLLNLTCSPGTVRPILEAFGPFE-----GGVIFSASAGEGHAGDLDLTIQVPRAIDDPYTHALTHGFV-PHTDHPVSTLLSDLKEHVS-VDEFLIDFGVIAGFNKIYVHFP-RDLQGVAQLAALPSMPRALADNAQLFARH-GLD--KVAMLSIDYHKRTINPFFTF-------PNGLEAKTISSLLHEFGVEEPD--------EE----LVESS-SKIFRAYPTLGWESSKIDRISFA-------RSLDLPTIRP---------RV--APEI---VRFVTGT---PYTYDGD-RFSISIVKWSPDDT-WFNVGSYF--QFGPLQREVLGKVLR----------------------- Streptomyces_sp._CNT371_2516112034 ---------------------MTDTG-ME----GLYAAIEEASGLLDIAPSRDKVWPILSAYE--L-EK--VVVAFRVTT--RGSKDLDCRFTALPADVNPYRYAVSKGIA-EATDHPVGTLLDDVQANIP-VTAHGVDFGVVEGFRKTWTFLPGNDLQKLSKVAALPSMPPSLAENLDFYARY-GLDD-KNSMIGIDYPSRTVNVYFLQ-----FPDETRAPETVRAMLRDLGLPEPS--------EQ----MLTLA-KQAVGIYTTLTWDSPKIQRITFAT------LVPDAEALPG---------RIALEPSV---EKFARNV---PHTYPGP-VQGLYNVASYSGGE-YFKLQTYH--QLAEGSLEARVLLGPAGSGS------------------ Streptomyces_sp._CNT371_2516112035 -----------VIGIDFLECLVSEGIEAE----GLYSAIEESARMVDAPFSRDKVWPILSAFGGGFSDA--GGVIFSLQAG-KDVPEMEYSAQISAEVGDPYAHALAAGVL-NETDHPVSTVLAEIVSAAP-TSEHYIDCGIVGGFKKIYANFP-HDQQKVSRLADLPAMPRAVGANAEFFDRY-GLD--NVALIGVDYRNKTINLYFQAPA---ETAGNLDPKTVSAMLRETGMSTPS--------EE----MVAYA-GRAYRIYATLGWDSPEVMRLAFAPQPR---RSIDLAELPA---------RL--EPRI---EQFMRAT---PHKYAGA-LINATAAKWSKKHE-VLDLAAYY--QVSALHLKAIQAEEGQSS-------------------- Streptomyces_sp._CNX435_2561476450 ---------------------MSATVEMD----ELYSVIEQSARTLGVPCAPETVRPVLAAYADTF-GHAATVVAFRVATSIRHAGELDCRFTTHPEEREPYATALAAGLA-RRTDHPAGAVLAQLQGRCH-VDSHGIDFGVVGGFKKVYAFFTPDDLQEISKIADLPAMPRALAGHAGFFARH-GLAD-RVGVVGVDYGHRTLNVYFND-----VPARLFEPGTIAATLDELGMARPS--------EQ----MLKLG-REAFGLYVTLGWDSPRIERICYAV------TTADLAALPV---------PV--EPEI---ERFVRGV---PAGDGD--RKFVYGVAVAPEGE-YYKLESHY--RWKPGTMDFI---------------------------- Streptomyces_sp._CNX435_2561478010 ---------------------MPDATKLE----TVYSAIEETARLVDAPCSREKVWPALDTFGRWF-DD--SHIIFSMGTGKKYRGELAFDFTVPTEAGDPYAAAVADGLL-EKVDHPITGLFSEIADRLP-LDAYAVDFGVARGFKKACVFFPLAQPASMKALAELPSIPPALAEHADFFAAA-GLDG-KVSCIGIDYGSRTWNLYVSG-----LTPEFTQRDAIGETLRGMGLPEPS--------EQ----MGEFI-STSFALYPTFGWDTTRVERMCFST------RTSDPNLLPA---------RI--EPDI---AKFARDM---PTVHSGE-PSYVYAGTVARGGE-FFKLASYY--QFSSQVSERVRPAD------------------------ Streptomyces_sp._CNX435_2561479929 ---------------------MSGANDVE----RVYSAMEEAAGLLNVPVARDKIWPVLTAYQDAL-AD--AVVVFSMAGG-RRATELDFSISVPTDLGDPFTTALRRGLT-EKTNHPVDNLLAELTDGFE-IGMYAIDGMVTTGFKKTYASFPTNEPQPLTALLDVPSMPESARANAELFARY-GLD--KVQMVSVDYPKRQVNLYFSE-----LDTDYLQPEHVKSLARETGLVEPT--------EM----GLDFA-SGSFAVYPTLGYDNDIVDRITYAV------ISVDPTLAPT---------KS--EPEVSQLSRYATSA---PYAYAGENRTLVYGVTLTSKEE-YYKLGSYY--QITDLQRTLVKAFEALD--------------------- Streptomyces_sp._CNX435_2561481643 ---------------------MTVNPGIE----RLCEAAEEAARQVGLDCPREKMTAVLTAFPNVV-TD--STVVFNIVNKGGRVGDMSFDFTVPLAEGDPYERALAHGLA-EETDHPVRGMFADMLATLP-VDCYGVDYGVNGGFNKAYAVFPMGRLQELSKLAAVPAMADTLSKWLGTLAGY-GLDG-KVSTVAIDHANRTWNVYFNG-----LSSQHFERATVQAMLRDFGLPKPS--------GQ----LLDFA-ETSSALYPTFSWDSPEIERVSFST------RTTDPAALPA---------HI--EPKL---GVLAANA---PYTYDGD-RKLVFAGALTTGGE-YYKLATYY--QMATDAHDRVRRGS------------------------ Streptomyces_sp._CNY243_2518513180 ---------------------MPEATELE----TIYSAVEETARLVDAPCSRDRVWPALDTFGKWL-DD--AHIIFSMGTGNRYRGELAFDFSLPKAAGDPYAAALAGGLL-DKVDHPIAGLLPEIRDRFT-VDAYGVDFGIVGGFRKAVAFFPLAEPQSMKALTELSSIPPALAEHAESFGAA-GLDG-KVSAIGVDYRSRSWNLYISG-----LTPEYTRPDAIIPTLRGMGLPEPS--------EH----MLEFI-GTSYAMYPTFGWDSTRIERMCFST------RTSDPDLLPA---------RI--EPAV---GKFAREM---PTVHKGE-PSYVYAGTVARGEE-FFKLASYY--QMSSQVSDRVRPAD------------------------ Streptomyces_sp._CNY243_2518518536 ---------------------MSATAETD----ELYSVIEQSARTLGVPCEPGTVRPVLTAYADAF-GHEAAVVAFRVATSLRHAGELDCRFTTHPEERDPYATALAAGLT-RPTDHPVGAVLAQVQGRCR-VDSHGVDFGVVGGFKKVYAFFTPDDLQDLAKFADLPAMPPALAAHADFFARH-GLAD-RVGVIGVDYHHRTLNVYFND-----VPPRLFEPDAITATLRELGMAAPS--------GH----MLKLG-REAFGLYVTVGWDTPRIERICYAV------TTPDLAALPV---------RV--EPEI---ERFVRGV---PAGDGD--RKFVYGVAVAPGGE-YYKLESHY--RWRAGTMDFI---------------------------- Streptomyces_sp._CNY243_2518518703 ---------------------MSAQADIE----TVHSAIEEAAGLLNLTCSPGTVRPILEAFGPFE-----GGVIFSASAGEGHAGDLDLTIQVPRAIDDPYTHALTHGFV-PHTDHPVSTLLSDLKEHVS-VDEYLIDFGVIAGFNKIYVHFP-RDLQGVAQLAALPSMPRALADNAELFARH-GLD--NVAMLSIDYHKRTINPFFTF-------SNGLEAKTISSLLHELGVVEPD--------EE----LVESS-SKIFRAYPTLGWESSKIDRISFA-------RSLDLPTIRP---------RV--EPEI---VRFVTGT---PYTYDGE-RFSISIVKWSPDDT-WFNVGSYF--QFGPRQREVLGKVLR----------------------- Streptomyces_sp._CNY243_2518518936 --------------------------------------------MVDAPFSRDKVWPTLSAFEGGFSDA--GGVILSLQAG-THVPEMEYSAQVSPGISDPYARALASGIL-TETDHPVSTVLAEIVSLAP-TSEHYIDCGIVGGFKKIYANFP-HDQQTVAALAGLPSMPRAVGGNAEFFARH-GLD--RVALIGVDYVNKTINLYFQVSA---ATAGNLDQKTVSAMLHETGMSEPS--------DA----MVAYA-CQAYRIYTTLSWDAEEILRIAFAPKPR---RGIDPADLPA---------RL--EPRI---EKFLRAT---PHKYPGA-LINATAAKWSPERE-VLDLAAHY--QVSAVQMKAIEAEEGQAS-------------------- Streptomyces_sp._CNY243_2518518937 ---------------------MTDTG-ME----GLYAAIEEASGLLDVAPSRDKVWPILSAYE--L-DK--VVVAFRVTT--RGSKDLDCRFTALPADVNPYRYAVSKGIA-EATDHPVGTLLDDVQANIP-VTAHGVDFGVVEGFRKTWTFLPGNDLQKLSKVAALPSMPPSLAENLDFYARY-GLDD-KNSMIGIDYPSRTVNVYFLQ-----FPDETREPETVRAMLRDLGLPEPS--------EQ----MLTLA-KQAVGIYTTLTWDSPKIQRITFAT------LVPDAEALPG---------RIAVEPSV---EKFARNV---PHTYPGP-VQGLYNVASYSGGE-YFKLQTYH--QLAEGSLEARVLLGAAGAGS------------------ 'Streptomyces sp. Cl190 1ZB6_A NphB' ---------------------MSEAADVE----RVYAAMEEAAGLLGVACARDKIYPLLSTFQDTL-VEGGSVVVFSMASG-RHSTELDFSISVPTSHGDPYATVVEKGLF-PATGHPVDDLLADTQKHLP-VSMFAIDGEVTGGFKKTYAFFPTDNMPGVAELSAIPSMPPAVAENAELFARY-GLD--KVQMTSMDYKKRQVNLYFSE-----LSAQTLEAESVLALVRELGLHVPN--------EL----GLKFC-KRSFSVYPTLNWETGKIDRLCFAV------ISNDPTLVPS---------SD--EGDI---EKFHNYATKAPYAYVGEKRTLVYGLTLSPKEE-YYKLGAYY--HITDVQRGLLKAFDSLED-------------------- Streptomyces_sp._KO3988_BAE78975_Fur7 ---------------------MPGTDDVAVDVASVYSAIEKSAGLLDVTAAREVVWPVLTAFEDVL-EQ--AVIAFRVATNARHEGDFDVRFTVP-EEVDPYAVALSRSLI-AKTDHPVGSLLSDIQQLCS-VDTYGVDLGVKSGFKKVWVYFPAGEHETLARLTGLTSMPGSLAGNVDFFTRY-GLAD-KVDVIGIDYRSRTMNVYFAA------PSECFERETVLAMHRDIGLPSPS--------EQ----MFKFC-ENSFGLYTTLNWDTMEIERISYGV------KTENPMTFFA---------RL--GTKV---EHFVKNV---PYGVDT--QKMVYAAVTSSGEE-YYKLQSYY--RWRSVSRLNAAYIAARDKEST----------------- Streptomyces_vitaminophilus_DSM_41686_2515785691 ---------------------MSGTAELP----GLYTALEESARLLDVTCSRDRVWPILTAYGDVL-PR--AVIAFRVATGSRHEGELDCRFLSLPGDVDPYAVAVSNGLT-AETDHPAGALLSDIQQRCP-IDSYGIDFGVVGGFKKTWSFFPGDDFQELSKLADIASMPRGLAENAGFFARY-GLDD-RVSLVGIDYPHRTVNVYFGE-----LPPECLEPEAIRSMHRDLDLPEPS--------EQ----MLGLS-QESFGLYVTLSWDSPKIKRISFGV------MTPDPQTLPG---------RL--DPKI---EHFVKND---PYGAAA--PKVVYVAMSSTEGE-YYKLQSYY--RWRPRMLDLMQVSDDTEDPA------------------ ; END; [ The following blocks are output data for analysis step 17336 ] BEGIN TREES; TITLE Streptomyces_Orf2_prenyltransferase_phylogeny; LINK TAXA = TaxaForAnalysisStep17336; TREE Orf2 = [&R] (((Streptomyces_roseochromogenes_oscitans_DS_12.976_AAN65239_CloQ:0.07691900489017722,Streptomyces_niveus_DSM_40088_AAF67510_NovQ:0.1284838695843765):0.7121626725970468,(Aspergillus_terreus_NIH2624_EAU39467_PtfAt:1.0710478425805983,(Botryotinia_fuckeliana_B05.10_EDN25735_PtfBf:0.15935194136460976,Sclerotinia_sclerotiorum_1980_EDN93598_PtfSs:0.06752410151380873)100:0.3864135814287891)54:0.2445458530745995)100:0.6655521009997607,(('Streptomyces gancidicus BKS 13_15 2539351921':0.12540188200741692,(Streptomyces_lividans_TK24_645400867:0.007212309755356725,'Streptomyces coelicolor A3_2 637271461':9.3905322139818E-7)88:0.08441129831261007)100:1.3244974731699761,(((Streptomyces_griseoflavus_Tu4000_645416841:0.40164488175628515,((Streptomyces_sp._CNX435_2561476450:0.03577632622205219,(Streptomyces_sp._CNB632_2561472124:0.014632779328372442,Streptomyces_sp._CNH099_2516099186:0.004129022748426184)96:0.03088697867310746)89:0.05286399532735236,(Streptomyces_sp._CNT371_2516104881:0.015533288953214201,(Streptomyces_sp._CNQ525_2562121671:0.0075830527799763845,(Streptomyces_sp._CNQ766_2518005124:0.0075641370560241864,(Streptomyces_sp._CNS335_2518010821:9.3905322139818E-7,(Streptomyces_sp._CNY243_2518518536:9.3905322139818E-7,Streptomyces_sp._CNQ865_2524593636_:9.3905322139818E-7)35:9.3905322139818E-7)76:9.3905322139818E-7)86:0.00758388992632758)82:0.007353110166802683)100:0.07644287314338645)100:0.2928087628262316)83:0.14156953776469045,(((Streptomyces_sp._CNB632_2561473004:0.025739770681284916,Streptomyces_sp._CNH099_2516101746:0.00600529902689272)100:0.8755238745523257,(Streptomyces_mobaraensis_NBRC_13819_2538963887:0.11528218679704617,'Streptomyces acidiscabies 84_104 2547553903':0.20008494492509118)100:0.4150546432237362)41:0.10922833210582528,((Streptomyces_sp._CNH287_2524588539:0.23012625394254832,(Streptomyces_cinnamonensis_DSM_1042_ADQ43372_EpzP_:0.43494054456574993,(Streptomyces_sp._CNS654_2562084974_:0.04842018378936178,Streptomyces_anulatus_9663_CAX48655_PpzP_:0.045441048140496834)100:0.20999754911223625)100:0.35703701312184105)22:0.045625303959767695,(Streptomyces_vitaminophilus_DSM_41686_2515785691:0.2615225124990981,((('Streptomyces sp. CNQ509 AA958_12635 ':0.11324982783889453,(Streptomyces_sp._CNB632_2561476125:0.035009253598517934,Streptomyces_sp._CNH099_2516104521:0.015638223044636787)100:0.11478582506711715)100:0.3628285499709069,(Streptomyces_cinnamonensis_DSM_1042_CAL34104_Fnq26:0.2513993114553184,(Streptomyces_davawensis_JCM_4913_2562412110:0.14107820787132186,Streptomyces_sp._KO3988_BAE78975_Fur7:0.11943847670324917)100:0.17519379135742216)100:0.31260979139815237)46:0.08926959156450652,((Streptomyces_sp._CNP082_2527270866:0.059371091995962806,Streptomyces_sp._CNQ329_2528491789:0.04964240692025997)67:0.0047171884135077955,(Streptomyces_sp._CNT371_2516112034:0.010690467089765898,(Streptomyces_aculeolatus_NRRL_18422_ABS50461_NapT8:9.3905322139818E-7,(Streptomyces_sp._CNY243_2518518937:9.3905322139818E-7,(Streptomyces_sp._CNQ525_2562123520:9.3905322139818E-7,(Streptomyces_sp._CNQ865_2524600745:9.3905322139818E-7,(Streptomyces_sp._CNQ766_2518006640:9.3905322139818E-7,Streptomyces_sp._CNS335_2518013945:9.3905322139818E-7)22:9.3905322139818E-7)11:9.3905322139818E-7)13:9.3905322139818E-7)83:9.3905322139818E-7)97:0.010520227307727519)75:0.024129237458149617)100:0.5728159808173072)18:0.034369678874516724)33:0.09015018186565027)28:0.062447931467734676)16:0.057649048809833896)43:0.1217348236645564,(((Streptomyces_sp._303MFCol52_2521683684:0.4446767336535419,(('Streptomyces sp. CNQ509 AA958_24325':0.23266856437265435,'Streptomyces sp. Cl190 1ZB6_A NphB':0.280117949152298)69:0.08091386486668352,('Streptomyces sp. CNQ509 AA958_18620':0.06453675093093755,(Streptomyces_sp._CNX435_2561479929:0.05511986396440957,(Streptomyces_sp._CNB632_2561473755:0.006423690321261038,Streptomyces_sp._CNH099_2516101115:0.007044583290957857)100:0.06598053205970188)99:0.0711713536250153)100:0.26451267102098347)77:0.11975701081186449)100:0.19550834812301587,((Streptomyces_sp._CNQ329_2528491298:0.09513133269949027,Streptomyces_sp._CNP082_2527270384:0.04431690230298052)100:0.7167930133560517,((Streptomyces_sp._303MFCol52_2521683528:0.11088320652413923,('Streptomyces sp. CNQ509 AA958_12645':0.10527677729666847,(Streptomyces_sp._CNX435_2561481643:0.05286888310392087,(Streptomyces_sp._CNB632_2561473002:0.014992880522704378,Streptomyces_sp._CNH099_2516101748:0.014532267796778773)100:0.0705428940629863)93:0.051602414262969)100:0.44696732062497535)100:0.317011915881733,((Streptomyces_sp._CNX435_2561478010:0.10889333553153384,(Streptomyces_sp._CNB632_2561470561:0.005356899030336226,Streptomyces_sp._CNH099_2516097927:0.020406420561452365)98:0.04821222715122285)82:0.03617284870997268,('Streptomyces sp. CNQ509 AA958_30735':0.060740587176388056,(Streptomyces_sp._CNT371_2516108106:0.005706085655682301,(Streptomyces_sp._CNQ525_2562118558:0.003636645751167011,((Streptomyces_sp._CNQ766_2518002741_:9.3905322139818E-7,Streptomyces_sp._CNQ865_2524596589:9.3905322139818E-7)21:9.3905322139818E-7,(Streptomyces_sp._CNY243_2518513180:9.3905322139818E-7,Streptomyces_sp._CNS335_2518010999:9.3905322139818E-7)27:9.3905322139818E-7)63:9.3905322139818E-7)100:0.01636836981123742)100:0.08654663044222359)81:0.06112658468328183)100:0.49586705237363504)99:0.1388155081268055)92:0.141145662338636)39:0.07317314798878219,(Streptomyces_sp._CNH287_2524586714:0.2613193583856133,(((Streptomyces_sp._CNQ525_2562123443:0.021547732266645154,(Streptomyces_sp._CNT371_2516111586:0.02556716110116471,Streptomyces_sp._CNQ329_2528489393:0.01476286385485084)24:0.00417923199091078)40:0.014433967995692286,((Streptomyces_sp._CNQ766_2518006200:9.3905322139818E-7,Streptomyces_sp._CNQ865_2524600624:9.3905322139818E-7)68:0.003561349310316978,(Streptomyces_sp._CNY243_2518518703:9.3905322139818E-7,Streptomyces_sp._CNS335_2518013585:9.3905322139818E-7)62:9.3905322139818E-7)90:9.3905322139818E-7)100:0.6786971881160915,((Streptomyces_sp._CNH189_2515835839:0.3471052626557071,(('Streptomyces sp. CNQ509 AA958_12625 ':0.1389355918490891,(Streptomyces_sp._CNB632_2561476124:0.017747658541210534,Streptomyces_sp._CNH099_2516104522:0.010226427919885612)100:0.2236444880092424)100:0.39578925958139605,('Streptomyces sp. CNQ509 AA958_24270 ':0.11892872729674146,(Streptomyces_sp._CNB632_2561476030:0.008419554854390297,Streptomyces_sp._CNH099_2516104298:0.020425727958419987)95:0.040057158430549265)100:0.19455142349251003)51:0.0557482131611902)90:0.13022849573711665,((Streptomyces_sp._CNP082_2527270867:0.11373667098033369,(Streptomyces_sp._CNQ329_2528491790:0.05846442705430063,Streptomyces_sp._CNT371_2516112035:0.08163157084284138)84:0.049680069204039896)60:0.04578269875110194,(Streptomyces_sp._CNQ525_2562123521:9.3905322139818E-7,(Streptomyces_sp._CNQ766_2518006639:9.3905322139818E-7,(Streptomyces_sp._CNQ865_2524600746_:9.3905322139818E-7,(Streptomyces_sp._CNY243_2518518936:9.3905322139818E-7,(Streptomyces_sp._CNS335_2518014051:9.3905322139818E-7,Streptomyces_aculeolatus_NRRL_18422_ABS50462_NapT9:9.3905322139818E-7)96:9.3905322139818E-7)27:9.3905322139818E-7)30:9.3905322139818E-7)78:0.003691421674154318)100:0.10325834774121682)100:0.5815939926116744)60:0.11706510119335203)99:0.2866902477154784)36:0.01823149449741421)88:0.18181633047037007)98:0.6780740799200445)100:0.6655521009997607); [! TreeBASE tree URI: http://purl.org/phylo/treebase/phylows/tree/TB2:Tr91037] END;