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Citation for Study 12670

About Citation title: "Saccharomyces cerevisiae occurs in surprisingly diverged populations in natural environments remote from human activity".
About Study name: "Saccharomyces cerevisiae occurs in surprisingly diverged populations in natural environments remote from human activity".
About This study is part of submission 12670 (Status: Published).

Citation

Wang Q., Liu W., Liti G., Wang S., & Bai F. 2012. Saccharomyces cerevisiae occurs in surprisingly diverged populations in natural environments remote from human activity. Molecular Ecology, 21(22): 5404-5417.

Authors

  • Wang Q. (submitter) Phone 81-10-64807352
  • Liu W.
  • Liti G.
  • Wang S.
  • Bai F.

Abstract

As a most-used model system in eukaryotic genetics, genomics and molecular biology, Saccharomyces cerevisiae is becoming a powerful tool to illuminate ecological and evolutionary principles. However, little is known about the ecology and population structure of the species in nature. We presented a field survey of the yeast at an unprecedented scale and performed population genetics analysis based on sequences of nine genes and four intergenic loci from Chinese wild isolates representing different ecological and geographical origins. A set of world-wide isolates representing the maximum genetic variation of S. cerevisiae documented so far, were also included. Here we show for the first time that S. cerevisiae is a ubiquitous species in nature, occurring in highly diversified substrates from human-associated environments as well as habitats remote from human activity. Chinese isolates of S. cerevisiae exhibited strong population structure with much more (nearly double) genetic variation than those from the rest of the world together. We identified eight new distinct wild lineages (CHN I-VIII) from a set of 99 Chinese isolates characterized. Isolates from primeval forests occurred in ancient and significantly diverged basal lineages, while those from human-associated environments usually clustered in less differentiated domestic or mosaic groups. Wild S. cerevisiae lineages exhibited lineage-specific karyotypes and partial reproductive isolation. The results suggest that wild S. cerevisiae populations have existed independently all along predating domestication and differentiated greatly in nature, and that China harbors a natural reservoir of S. cerevisiae genetic variation, which is perhaps a signature of its origin.

Keywords

Fungi, Population Genetics - Empirical, Population Ecology, Phylogeography

External links

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  • Canonical resource URI: http://purl.org/phylo/treebase/phylows/study/TB2:S12670
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