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Citation for Study 14909

Citation title: "Dynamic evolution of mitochondrial ribosomal proteins in Holozoa".

Study name: "Dynamic evolution of mitochondrial ribosomal proteins in Holozoa".

This study is part of submission 14909 (Status: Published).

Citation

Scheel B.M., & Hausdorf B. 2014. Dynamic evolution of mitochondrial ribosomal proteins in Holozoa. Molecular Phylogenetics and Evolution, 76: 67-74.

Authors

• Scheel B.M. (submitter)
• Hausdorf B.

Abstract

We studied the highly dynamic evolution of mitochondrial ribosomal proteins (MRPs) in Holozoa. Most major clades within Holozoa are characterized by gains and/or losses of MRPs. The usefulness of gains of MRPs as rare genomic changes in phylogenetics is undermined by the high frequency of secondary losses. However, phylogenetic analyses of the MRP sequences provide evidence for the Acrosomata hypothesis, a sister group relationship between Ctenophora and Bilateria. An extensive restructuring of the mitochondrial genome and, as a consequence, of the mitochondrial ribosomes occurred in the ancestor of metazoans. The last MRP genes encoded in the mitochondrial genome were either moved to the nuclear genome or were lost. The strong decrease in size of the mitochondrial genome was probably caused by selection for rapid replication of mitochondrial DNA during oogenesis in the metazoan ancestor. A phylogenetic analysis of MRPL56 sequences provided evidence for a horizontal gene transfer of the corresponding MRP gene between metazoans and Dictyostelidae (Amoebozoa). The hypothesis that the requisition of additional MRPs compensated for a loss of rRNA segments in the mitochondrial ribosomes is corroborated by a significant negative correlation between the number of MRPs and length of the rRNA. Newly acquired MRPs evolved faster than bacterial MRPs and positions in eukaryote-specific MRPs were more strongly affected by coevolution than positions in prokaryotic MRPs in accordance with the necessity to fit these proteins into the pre-existing structure of the mitoribosome.

Keywords

Holozoa, Metazoa, Ctenophora, mitochondrial ribosomal proteins, horizontal gene transfer, coevolution

External links

• DOI: 10.1016/j.ympev.2014.03.005
• Other URL: http://www.sciencedirect.com/science/article/pii/S1055790314000979

About this resource

• Canonical resource URI: http://purl.org/phylo/treebase/phylows/study/TB2:S14909
• Other versions: Nexus NeXML
• Show BibTeX reference

  		@ARTICLE{TreeBASE2Ref22542,
  	 author = {Bettina M. Scheel and Bernhard  Hausdorf},
  	 title = {Dynamic evolution of mitochondrial ribosomal proteins in Holozoa},
  	 year = {2014},
  	 keywords = {Holozoa, Metazoa, Ctenophora, mitochondrial ribosomal proteins, horizontal gene transfer, coevolution},
  	 doi = {10.1016/j.ympev.2014.03.005},
  	 url = {http://www.sciencedirect.com/science/article/pii/S1055790314000979},
  	 pmid = {},
  	 journal = {Molecular Phylogenetics and Evolution},
  	 volume = {76},
  	 number = {},
  	 pages = {67--74},
  	 abstract = {We studied the highly dynamic evolution of mitochondrial ribosomal proteins (MRPs) in Holozoa. Most major clades within Holozoa are characterized by gains and/or losses of MRPs. The usefulness of gains of MRPs as rare genomic changes in phylogenetics is undermined by the high frequency of secondary losses. However, phylogenetic analyses of the MRP sequences provide evidence for the Acrosomata hypothesis, a sister group relationship between Ctenophora and Bilateria. An extensive restructuring of the mitochondrial genome and, as a consequence, of the mitochondrial ribosomes occurred in the ancestor of metazoans. The last MRP genes encoded in the mitochondrial genome were either moved to the nuclear genome or were lost. The strong decrease in size of the mitochondrial genome was probably caused by selection for rapid replication of mitochondrial DNA during oogenesis in the metazoan ancestor. A phylogenetic analysis of MRPL56 sequences provided evidence for a horizontal gene transfer of the corresponding MRP gene between metazoans and Dictyostelidae (Amoebozoa). The hypothesis that the requisition of additional MRPs compensated for a loss of rRNA segments in the mitochondrial ribosomes is corroborated by a significant negative correlation between the number of MRPs and length of the rRNA. Newly acquired MRPs evolved faster than bacterial MRPs and positions in eukaryote-specific MRPs were more strongly affected by coevolution than positions in prokaryotic MRPs in accordance with the necessity to fit these proteins into the pre-existing structure of the mitoribosome.}
  }
  		

• Show RIS reference

  		TY  - JOUR
  ID  - 22542
  AU  - Scheel,Bettina M.
  AU  - Hausdorf,Bernhard 
  T1  - Dynamic evolution of mitochondrial ribosomal proteins in Holozoa
  PY  - 2014
  KW  - Holozoa
  KW  - Metazoa
  KW  - Ctenophora
  KW  - mitochondrial ribosomal proteins
  KW  - horizontal gene transfer
  KW  - coevolution
  UR  - http://www.sciencedirect.com/science/article/pii/S1055790314000979
  N2  - We studied the highly dynamic evolution of mitochondrial ribosomal proteins (MRPs) in Holozoa. Most major clades within Holozoa are characterized by gains and/or losses of MRPs. The usefulness of gains of MRPs as rare genomic changes in phylogenetics is undermined by the high frequency of secondary losses. However, phylogenetic analyses of the MRP sequences provide evidence for the Acrosomata hypothesis, a sister group relationship between Ctenophora and Bilateria. An extensive restructuring of the mitochondrial genome and, as a consequence, of the mitochondrial ribosomes occurred in the ancestor of metazoans. The last MRP genes encoded in the mitochondrial genome were either moved to the nuclear genome or were lost. The strong decrease in size of the mitochondrial genome was probably caused by selection for rapid replication of mitochondrial DNA during oogenesis in the metazoan ancestor. A phylogenetic analysis of MRPL56 sequences provided evidence for a horizontal gene transfer of the corresponding MRP gene between metazoans and Dictyostelidae (Amoebozoa). The hypothesis that the requisition of additional MRPs compensated for a loss of rRNA segments in the mitochondrial ribosomes is corroborated by a significant negative correlation between the number of MRPs and length of the rRNA. Newly acquired MRPs evolved faster than bacterial MRPs and positions in eukaryote-specific MRPs were more strongly affected by coevolution than positions in prokaryotic MRPs in accordance with the necessity to fit these proteins into the pre-existing structure of the mitoribosome.
  L3  - 10.1016/j.ympev.2014.03.005
  JF  - Molecular Phylogenetics and Evolution
  VL  - 76
  IS  - 
  SP  - 67
  EP  - 74
  ER  -