@ARTICLE{TreeBASE2Ref24349,
author = {alex twyford and Jannice Friedman},
title = {Adaptive divergence in the monkey flower Mimulus guttatus is maintained by a chromosomal inversion},
year = {2015},
keywords = {chromosome inversion, adaptation, population genomics, Mimulus, phylogeography},
doi = {},
url = {http://},
pmid = {},
journal = {Evolution},
volume = {},
number = {},
pages = {},
abstract = {Organisms exhibit an incredible diversity of life history strategies as adaptive responses to environmental variation. The establishment of novel life history strategies involves multilocus polymorphisms, which will be challenging to establish in the face of gene flow and recombination. Theory predicts that adaptive allelic combinations may be maintained and spread if they occur in genomic regions of reduced recombination, such as chromosomal inversion polymorphisms, yet empirical support for this prediction is lacking. Here, we use genomic data to investigate the evolution of divergent adaptive ecotypes of the yellow monkey flower Mimulus guttatus. We show a large chromosomal inversion polymorphism is the major region of divergence between geographically widespread annual and perennial ecotypes. In contrast, ~40,000 SNPs in collinear regions of the genome show no signal of life history, revealing genomic patterns of diversity have been shaped by localised homogenizing gene flow and large-scale Pleistocene range expansion. Our results provide evidence for an inversion capturing and protecting loci involved in local adaptation, while also explaining how adaptive divergence can occur with gene flow.}
}
Citation for Study 17291
Citation title:
"Adaptive divergence in the monkey flower Mimulus guttatus is maintained by a chromosomal inversion".
Study name:
"Adaptive divergence in the monkey flower Mimulus guttatus is maintained by a chromosomal inversion".
This study is part of submission 17291
(Status: Published).
Citation
Twyford A., & Friedman J. 2015. Adaptive divergence in the monkey flower Mimulus guttatus is maintained by a chromosomal inversion. Evolution, .
Authors
-
Twyford A.
(submitter)
07783408245
-
Friedman J.
Abstract
Organisms exhibit an incredible diversity of life history strategies as adaptive responses to environmental variation. The establishment of novel life history strategies involves multilocus polymorphisms, which will be challenging to establish in the face of gene flow and recombination. Theory predicts that adaptive allelic combinations may be maintained and spread if they occur in genomic regions of reduced recombination, such as chromosomal inversion polymorphisms, yet empirical support for this prediction is lacking. Here, we use genomic data to investigate the evolution of divergent adaptive ecotypes of the yellow monkey flower Mimulus guttatus. We show a large chromosomal inversion polymorphism is the major region of divergence between geographically widespread annual and perennial ecotypes. In contrast, ~40,000 SNPs in collinear regions of the genome show no signal of life history, revealing genomic patterns of diversity have been shaped by localised homogenizing gene flow and large-scale Pleistocene range expansion. Our results provide evidence for an inversion capturing and protecting loci involved in local adaptation, while also explaining how adaptive divergence can occur with gene flow.
Keywords
chromosome inversion, adaptation, population genomics, Mimulus, phylogeography
External links
About this resource
- Canonical resource URI:
http://purl.org/phylo/treebase/phylows/study/TB2:S17291
- Other versions:
Nexus
NeXML
- Show BibTeX reference
@ARTICLE{TreeBASE2Ref24349,
author = {alex twyford and Jannice Friedman},
title = {Adaptive divergence in the monkey flower Mimulus guttatus is maintained by a chromosomal inversion},
year = {2015},
keywords = {chromosome inversion, adaptation, population genomics, Mimulus, phylogeography},
doi = {},
url = {http://},
pmid = {},
journal = {Evolution},
volume = {},
number = {},
pages = {},
abstract = {Organisms exhibit an incredible diversity of life history strategies as adaptive responses to environmental variation. The establishment of novel life history strategies involves multilocus polymorphisms, which will be challenging to establish in the face of gene flow and recombination. Theory predicts that adaptive allelic combinations may be maintained and spread if they occur in genomic regions of reduced recombination, such as chromosomal inversion polymorphisms, yet empirical support for this prediction is lacking. Here, we use genomic data to investigate the evolution of divergent adaptive ecotypes of the yellow monkey flower Mimulus guttatus. We show a large chromosomal inversion polymorphism is the major region of divergence between geographically widespread annual and perennial ecotypes. In contrast, ~40,000 SNPs in collinear regions of the genome show no signal of life history, revealing genomic patterns of diversity have been shaped by localised homogenizing gene flow and large-scale Pleistocene range expansion. Our results provide evidence for an inversion capturing and protecting loci involved in local adaptation, while also explaining how adaptive divergence can occur with gene flow.}
}
- Show RIS reference
TY - JOUR
ID - 24349
AU - twyford,alex
AU - Friedman,Jannice
T1 - Adaptive divergence in the monkey flower Mimulus guttatus is maintained by a chromosomal inversion
PY - 2015
KW - chromosome inversion
KW - adaptation
KW - population genomics
KW - Mimulus
KW - phylogeography
UR - http://dx.doi.org/
N2 - Organisms exhibit an incredible diversity of life history strategies as adaptive responses to environmental variation. The establishment of novel life history strategies involves multilocus polymorphisms, which will be challenging to establish in the face of gene flow and recombination. Theory predicts that adaptive allelic combinations may be maintained and spread if they occur in genomic regions of reduced recombination, such as chromosomal inversion polymorphisms, yet empirical support for this prediction is lacking. Here, we use genomic data to investigate the evolution of divergent adaptive ecotypes of the yellow monkey flower Mimulus guttatus. We show a large chromosomal inversion polymorphism is the major region of divergence between geographically widespread annual and perennial ecotypes. In contrast, ~40,000 SNPs in collinear regions of the genome show no signal of life history, revealing genomic patterns of diversity have been shaped by localised homogenizing gene flow and large-scale Pleistocene range expansion. Our results provide evidence for an inversion capturing and protecting loci involved in local adaptation, while also explaining how adaptive divergence can occur with gene flow.
L3 -
JF - Evolution
VL -
IS -
ER -