CiteULike CiteULike
Delicious Delicious
Connotea Connotea

Citation for Study 22172

About Citation title: "The obligate alkalophilic soda-lake fungus Sodiomyces alkalinus has shifted to a protein diet".
About Study name: "The obligate alkalophilic soda-lake fungus Sodiomyces alkalinus has shifted to a protein diet".
About This study is part of submission 22172 (Status: Published).

Citation

Grum-grzhimaylo A.A., Falkoski D., Van den heuvel J., Valero-jim?nez C., Min B., Choi I., Lipzen A., Daum C., Aanen D., Tsang A., Henrissat B., Bilanenko E.N., De vries R., Van kan J., Grigoriev I.V., & Debets A.J. 2018. The obligate alkalophilic soda-lake fungus Sodiomyces alkalinus has shifted to a protein diet. Molecular Ecology, .

Authors

  • Grum-grzhimaylo A.A.
  • Falkoski D.
  • Van den heuvel J.
  • Valero-jim?nez C.
  • Min B.
  • Choi I.
  • Lipzen A.
  • Daum C.
  • Aanen D.
  • Tsang A.
  • Henrissat B.
  • Bilanenko E.N.
  • De vries R.
  • Van kan J.
  • Grigoriev I.V.
  • Debets A.J.

Abstract

Sodiomyces alkalinus is one of the very few alkalophilic fungi, adapted to grow optimally at high pH. It is widely distributed at the plant-deprived edges of extremely alkaline lakes and locally abundant. We sequenced the genome of S. alkalinus and reconstructed evolution of catabolic enzymes, using a phylogenomic comparison. We found that the genome of S. alkalinus is larger, but its predicted proteome is smaller and heavily depleted of both plant-degrading enzymes and proteinases, when compared to its closest plant-pathogenic relatives. Interestingly, despite overall losses, S. alkalinus has retained many proteinases families and acquired bacterial-cell-wall-degrading enzymes, some of them via horizontal gene transfer from bacteria. This fungus has very potent proteolytic activity at high pH values, but slowly-induced low activity of cellulases and hemicellulases. Our experimental and in silico data suggest that plant biomass, a common food source for most fungi, is not a preferred substrate for S. alkalinus in its natural environment. We conclude the fungus has abandoned the ancestral plant-based diet, and has become specialized in a more protein-rich food, abundantly available in soda lakes in the form of prokaryotes and small crustaceans.

Keywords

alkalophilic fungus, brine shrimps, enzymes, HGT, prokaryotes, Sodiomyces alkalinus

External links

About this resource

  • Canonical resource URI: http://purl.org/phylo/treebase/phylows/study/TB2:S22172
  • Other versions: Download Reconstructed NEXUS File Nexus Download NeXML File NeXML
  • Show BibTeX reference
  • Show RIS reference