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Citation for Study 12186

About Citation title: "A Molecular Phylogeny of Living Primates.".
About Study name: "A Molecular Phylogeny of Living Primates.".
About This study is part of submission 12186 (Status: Published).


Perelman P., Johnson W.E., Roos C., Seuá́nez H.N., Horvath J.E., Moreira M.A., Kessing B.D., Pontius J., Roelke M., Rumpler Y., Schneider M.C., Silva A., O'brien S., & Pecon-slattery J. 2011. A Molecular Phylogeny of Living Primates. PLoS Genetics, 7(3): e1001342.


  • Perelman P.
  • Johnson W.E.
  • Roos C.
  • Seuá́nez H.N.
  • Horvath J.E.
  • Moreira M.A.
  • Kessing B.D.
  • Pontius J.
  • Roelke M.
  • Rumpler Y.
  • Schneider M.C.
  • Silva A.
  • O'brien S.
  • Pecon-slattery J.


Comparative genomic analyses of primates offer considerable potential to define and understand the processes that mold, shape, and transform the human genome. However, primate taxonomy is both complex and controversial, with marginal unifying consensus of the evolutionary hierarchy of extant primate species. Here we provide new genomic sequence (,8 Mb) from 186 primates representing 61 (,90%) of the described genera, and we include outgroup species from Dermoptera, Scandentia, and Lagomorpha. The resultant phylogeny is exceptionally robust and illuminates events in primate evolution from ancient to recent, clarifying numerous taxonomic controversies and providing new data on human evolution. Ongoing speciation, reticulate evolution, ancient relic lineages, unequal rates of evolution, and disparate distributions of insertions/deletions among the reconstructed primate lineages are uncovered. Our resolution of the primate phylogeny provides an essential evolutionary framework with far-reaching applications including: human selection and adaptation, global emergence of zoonotic diseases, mammalian comparative genomics, primate taxonomy, and conservation of endangered species.

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