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Citation for Study 12813

Citation title: "RPB1 and RPB2 phylogeny supports an early Cretaceous origin and a strongly supported clade comprising all agriculturally and medically important fusaria".

Study name: "RPB1 and RPB2 phylogeny supports an early Cretaceous origin and a strongly supported clade comprising all agriculturally and medically important fusaria".

This study is part of submission 12813 (Status: Published).

Citation

O'donnell K., Rooney A., Proctor R.H., Brown D., Mccormick S.P., Ward T.J., Rehner S.A., Aoki T., Robert V., Crous P.W., Kang S., Geiser D., Frandsen R., & Lys?e E. 2012. RPB1 and RPB2 phylogeny supports an early Cretaceous origin and a strongly supported clade comprising all agriculturally and medically important fusaria. Fungal Genetics and Biology, .

Authors

• O'donnell K. 309-681-6383
• Rooney A.
• Proctor R.H.
• Brown D.
• Mccormick S.P.
• Ward T.J.
• Rehner S.A. 301050405326
• Aoki T.
• Robert V.
• Crous P.W.
• Kang S.
• Geiser D.
• Frandsen R.
• Lys?e E.

Abstract

Fusarium (Hypocreales, Nectriaceae) is one of the most economically important and systematically challenging groups of mycotoxigenic phytopathogens and emergent human pathogens. We conducted maximum likelihood (ML), maximum parsimony (MP) and Bayesian (B) analyses on partial RNA polymerase largest (RPB1) and second largest subunit (RPB2) nucleotide sequences of 94 fusaria to infer the first comprehensive and well-supported phylogenetic hypothesis of evolutionary relationships within the genus and 20 of its near relatives. Our analysis revealed that Cylindrocarpon formed a basal monophyletic sister to a ?terminal Fusarium clade? (TFC, sensu Gr?fenhan et al., 2011) comprising 20 strongly supported species complexes and nine monotypic lineages. The basal-most divergences within the TFC were only significantly supported by Bayesian posterior probabilities (B-PP = 0.99-1), with the ventricosum and dimerum species complexes forming the two earliest diverging lineages. An internode supporting the remaining TFC, however, was strongly supported by MP and ML bootstrapping (ML-BS 100%, MP-BS 87%) and by a B-PP of 1. By way of contrast, reanalysis of the Gr?fenhan et al. two-locus data set (portions of RPB2 and ATP citrate lyase) did not resolve any strongly supported relationship among the eight basal-most lineages within the TFC. Diversification time estimates date the origin of the TFC to the early Cretaceous 135.8 million years ago (Mya) (95% highest posterior density [HPD] interval: 85.3, 184.0). We also dated the evolutionary origin of several bioactive secondary metabolites, including three mycotoxins and the gibberellin phytohormones, and the economically devastating plant pathogenic lineage responsible for Fusarium head blight (FHB) of cereals. Dating of several plant-associated species complexes (e.g., fujikuroi, oxysporum, sambucinum, tricinctum and nisikadoi) suggests their evolution may have been driven by angiosperm diversification during the Miocene and Pliocene. Dating of the homothallic F. graminearum species complex (FGSC) of FHB pathogens suggests that it split from its heterothallic ancestors in the Pliocene 2.7 Mya [95% HPD interval: 0.5, 5.6] and that the most recent common ancestor of F. graminearum and F. asiaticum diverged 1.2 Mya [95% HPD interval: 0.16, 3.0]. In addition, evolutionary radiation of the vascular wilt pathogens within the oxysporum species complex was dated to the Pliocene 3.7 Mya [95% HPD interval: 0.4, 8.9]. Our phylogenetic results support the unitary application of the name Fusarium to the TFC and provide a robust framework for future comparative phylogenetic and genomic analyses of Fusarium.

Keywords

Bayesian inference; evolution; fumonisins; fusarins; gibberellins, maximum likelihood; maximum parsimony; molecular dating; mycotoxins; systematics; trichothecenes

External links

About this resource

• Canonical resource URI: http://purl.org/phylo/treebase/phylows/study/TB2:S12813
• Other versions: Nexus NeXML
• Show BibTeX reference

  		@ARTICLE{TreeBASE2Ref20785,
  	 author = {Kerry  O'Donnell and Alejandro  Rooney and Robert H. Proctor and Daren  Brown and Susan P. McCormick and Todd J. Ward and Stephen A Rehner and Takayuki  Aoki and Vincent  Robert and Pedro W. Crous and Seogchan  Kang and David M.  Geiser and Rasmus  Frandsen and Erik  Lys?e},
  	 title = {RPB1 and RPB2 phylogeny supports an early Cretaceous origin and a strongly supported clade comprising all agriculturally and medically important fusaria},
  	 year = {2012},
  	 keywords = {Bayesian inference; evolution; fumonisins; fusarins; gibberellins, maximum likelihood; maximum parsimony; molecular dating; mycotoxins; systematics; trichothecenes},
  	 doi = {},
  	 url = {http://},
  	 pmid = {},
  	 journal = {Fungal Genetics and Biology},
  	 volume = {},
  	 number = {},
  	 pages = {},
  	 abstract = {Fusarium (Hypocreales, Nectriaceae) is one of the most economically important and systematically challenging groups of mycotoxigenic phytopathogens and emergent human pathogens.  We conducted maximum likelihood (ML), maximum parsimony (MP) and Bayesian (B) analyses on partial RNA polymerase largest (RPB1) and second largest subunit (RPB2) nucleotide sequences of 94 fusaria to infer the first comprehensive and well-supported phylogenetic hypothesis of evolutionary relationships within the genus and 20 of its near relatives.  Our analysis revealed that Cylindrocarpon formed a basal monophyletic sister to a ?terminal Fusarium clade? (TFC, sensu Gr?fenhan et al., 2011) comprising 20 strongly supported species complexes and nine monotypic lineages.  The basal-most divergences within the TFC were only significantly supported by Bayesian posterior probabilities (B-PP = 0.99-1), with the ventricosum and dimerum species complexes forming the two earliest diverging lineages.  An internode supporting the remaining TFC, however, was strongly supported by MP and ML bootstrapping (ML-BS 100%, MP-BS 87%) and by a B-PP of 1.  By way of contrast, reanalysis of the Gr?fenhan et al. two-locus data set (portions of RPB2 and ATP citrate lyase) did not resolve any strongly supported relationship among the eight basal-most lineages within the TFC.  Diversification time estimates date the origin of the TFC to the early Cretaceous 135.8 million years ago (Mya) (95% highest posterior density [HPD] interval: 85.3, 184.0). We also dated the evolutionary origin of several bioactive secondary metabolites, including three mycotoxins and the gibberellin phytohormones, and the economically devastating plant pathogenic lineage responsible for Fusarium head blight (FHB) of cereals. Dating of several plant-associated species complexes (e.g., fujikuroi, oxysporum, sambucinum, tricinctum and nisikadoi) suggests their evolution may have been driven by angiosperm diversification during the Miocene and Pliocene.  Dating of the homothallic F. graminearum species complex (FGSC) of FHB pathogens suggests that it split from its heterothallic ancestors in the Pliocene 2.7 Mya [95% HPD interval: 0.5, 5.6] and that the most recent common ancestor of F. graminearum and F. asiaticum diverged 1.2 Mya [95% HPD interval: 0.16, 3.0].  In addition, evolutionary radiation of the vascular wilt pathogens within the oxysporum species complex was dated to the Pliocene 3.7 Mya [95% HPD interval: 0.4, 8.9].  Our phylogenetic results support the unitary application of the name Fusarium to the TFC and provide a robust framework for future comparative phylogenetic and genomic analyses of Fusarium.}
  }
  		

• Show RIS reference

  		TY  - JOUR
  ID  - 20785
  AU  - O'Donnell,Kerry 
  AU  - Rooney,Alejandro 
  AU  - Proctor,Robert H.
  AU  - Brown,Daren 
  AU  - McCormick,Susan P.
  AU  - Ward,Todd J.
  AU  - Rehner,Stephen A
  AU  - Aoki,Takayuki 
  AU  - Robert,Vincent 
  AU  - Crous,Pedro W.
  AU  - Kang,Seogchan 
  AU  - Geiser,David M. 
  AU  - Frandsen,Rasmus 
  AU  - Lys?e,Erik 
  T1  - RPB1 and RPB2 phylogeny supports an early Cretaceous origin and a strongly supported clade comprising all agriculturally and medically important fusaria
  PY  - 2012
  KW  - Bayesian inference; evolution; fumonisins; fusarins; gibberellins
  KW  - maximum likelihood; maximum parsimony; molecular dating; mycotoxins; systematics; trichothecenes
  UR  - http://dx.doi.org/
  N2  - Fusarium (Hypocreales, Nectriaceae) is one of the most economically important and systematically challenging groups of mycotoxigenic phytopathogens and emergent human pathogens.  We conducted maximum likelihood (ML), maximum parsimony (MP) and Bayesian (B) analyses on partial RNA polymerase largest (RPB1) and second largest subunit (RPB2) nucleotide sequences of 94 fusaria to infer the first comprehensive and well-supported phylogenetic hypothesis of evolutionary relationships within the genus and 20 of its near relatives.  Our analysis revealed that Cylindrocarpon formed a basal monophyletic sister to a ?terminal Fusarium clade? (TFC, sensu Gr?fenhan et al., 2011) comprising 20 strongly supported species complexes and nine monotypic lineages.  The basal-most divergences within the TFC were only significantly supported by Bayesian posterior probabilities (B-PP = 0.99-1), with the ventricosum and dimerum species complexes forming the two earliest diverging lineages.  An internode supporting the remaining TFC, however, was strongly supported by MP and ML bootstrapping (ML-BS 100%, MP-BS 87%) and by a B-PP of 1.  By way of contrast, reanalysis of the Gr?fenhan et al. two-locus data set (portions of RPB2 and ATP citrate lyase) did not resolve any strongly supported relationship among the eight basal-most lineages within the TFC.  Diversification time estimates date the origin of the TFC to the early Cretaceous 135.8 million years ago (Mya) (95% highest posterior density [HPD] interval: 85.3, 184.0). We also dated the evolutionary origin of several bioactive secondary metabolites, including three mycotoxins and the gibberellin phytohormones, and the economically devastating plant pathogenic lineage responsible for Fusarium head blight (FHB) of cereals. Dating of several plant-associated species complexes (e.g., fujikuroi, oxysporum, sambucinum, tricinctum and nisikadoi) suggests their evolution may have been driven by angiosperm diversification during the Miocene and Pliocene.  Dating of the homothallic F. graminearum species complex (FGSC) of FHB pathogens suggests that it split from its heterothallic ancestors in the Pliocene 2.7 Mya [95% HPD interval: 0.5, 5.6] and that the most recent common ancestor of F. graminearum and F. asiaticum diverged 1.2 Mya [95% HPD interval: 0.16, 3.0].  In addition, evolutionary radiation of the vascular wilt pathogens within the oxysporum species complex was dated to the Pliocene 3.7 Mya [95% HPD interval: 0.4, 8.9].  Our phylogenetic results support the unitary application of the name Fusarium to the TFC and provide a robust framework for future comparative phylogenetic and genomic analyses of Fusarium.
  L3  - 
  JF  - Fungal Genetics and Biology
  VL  - 
  IS  - 
  ER  -