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Citation for Study 12835

Citation title: "Mitochondrial capture by a transmissible cancer".

Study name: "Mitochondrial capture by a transmissible cancer".

This study is part of submission 12835 (Status: Published).

Citation

Rebbeck C.A., Leroi A.M., & Burt A. 2011. Mitochondrial capture by a transmissible cancer. Science, 331: 303.

Authors

• Rebbeck C.A.
• Leroi A.M.
• Burt A.

Abstract

Canine transmissible venereal tumor (CTVT) is an infectious cell line circulating in many feral dog populations. It originated once, about 10,000 years ago. Phylogenetic analyses of mitochondrial sequences from dogs, wolves, and a geographically diverse collection of CTVT samples indicate that the cancer has periodically acquired mitochondria from its host. We suggest that this may be because the cancer?s own mitochondria have a tendency to degenerate, due to high mutation rates and relaxed selection, resulting in host mitochondria being more fit.

External links

• DOI: 10.1126/science.1197696
• PMID: 21252340
• Other URL: http://dx.doi.org/10.5061/dryad.8081

About this resource

• Canonical resource URI: http://purl.org/phylo/treebase/phylows/study/TB2:S12835
• Other versions: Nexus NeXML
• Show BibTeX reference

  		@ARTICLE{TreeBASE2Ref20806,
  	 author = {Clare A. Rebbeck and Armand M. Leroi and Austin  Burt},
  	 title = {Mitochondrial capture by a transmissible cancer},
  	 year = {2011},
  	 keywords = {},
  	 doi = {10.1126/science.1197696},
  	 url = {http://dx.doi.org/10.5061/dryad.8081},
  	 pmid = {21252340 },
  	 journal = {Science},
  	 volume = {331},
  	 number = {},
  	 pages = {303},
  	 abstract = {Canine transmissible venereal tumor (CTVT) is an infectious cell line circulating in many feral dog populations. It originated once, about 10,000 years ago. Phylogenetic analyses of mitochondrial sequences from dogs, wolves, and a geographically diverse collection of CTVT samples indicate that the cancer has periodically acquired mitochondria from its host. We suggest that this may be because the cancer?s own mitochondria have a tendency to degenerate, due to high mutation rates and relaxed selection, resulting in host mitochondria being more fit.}
  }
  		

• Show RIS reference

  		TY  - JOUR
  ID  - 20806
  AU  - Rebbeck,Clare A.
  AU  - Leroi,Armand M.
  AU  - Burt,Austin 
  T1  - Mitochondrial capture by a transmissible cancer
  PY  - 2011
  KW  - 
  UR  - http://dx.doi.org/10.5061/dryad.8081
  N2  - Canine transmissible venereal tumor (CTVT) is an infectious cell line circulating in many feral dog populations. It originated once, about 10,000 years ago. Phylogenetic analyses of mitochondrial sequences from dogs, wolves, and a geographically diverse collection of CTVT samples indicate that the cancer has periodically acquired mitochondria from its host. We suggest that this may be because the cancer?s own mitochondria have a tendency to degenerate, due to high mutation rates and relaxed selection, resulting in host mitochondria being more fit.
  L3  - 10.1126/science.1197696
  JF  - Science
  VL  - 331
  IS  - 
  ER  -