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Citation for Study 18595

Citation title: "Whole Mitochondrial Genomes Unveil the Impact of Domestication on Goat Matrilineal Variability".

Study name: "Whole Mitochondrial Genomes Unveil the Impact of Domestication on Goat Matrilineal Variability".

This study is part of submission 18595 (Status: Published).

Citation

Colli L., Lancioni H., Cardinali I., Olivieri A., Capodiferro M., Pellecchia M., Rzepus M., Zamani W., Naderi S., Gandini F., Vahidi S., Agha S., Randi E., Battaglia V., Sardina M., Portolano B., Rezaei H., Lymberakis P., Boyer F., Coissac E., Pompanon F., Taberlet P., Ajmone marsan P., & Achilli A. 2015. Whole Mitochondrial Genomes Unveil the Impact of Domestication on Goat Matrilineal Variability. BMC Genomics, .

Authors

• Colli L.
• Lancioni H. (submitter) 0755855752
• Cardinali I.
• Olivieri A.
• Capodiferro M.
• Pellecchia M.
• Rzepus M.
• Zamani W.
• Naderi S.
• Gandini F.
• Vahidi S.
• Agha S.
• Randi E.
• Battaglia V.
• Sardina M.
• Portolano B.
• Rezaei H.
• Lymberakis P.
• Boyer F.
• Coissac E.
• Pompanon F.
• Taberlet P.
• Ajmone marsan P.
• Achilli A.

Abstract

Background The current extensive use of the domestic goat (Capra hircus) is the result of its medium size and high adaptability as multiple breeds. The extent to which its genetic variability was influenced by early domestication practices is largely unknown. A common standard by which to analyze maternally-inherited variability of livestock species is through complete sequencing of the entire mitogenome (mitochondrial DNA, mtDNA). Results We present the first extensive survey of goat mitogenomic variability based on 84 complete sequences selected from an initial collection of 758 samples that represent 60 different breeds of C. hircus, as well as its wild sister species, bezoar (Capra aegagrus) from Iran. Our phylogenetic analyses dated the most recent common ancestor of C. hircus to ~460 thousand years (ka) ago and identified five distinctive domestic haplogroups (A, B1, C1a, D1 and G). More than 90% of goats examined were in haplogroup A. These domestic lineages are predominantly nested within C. aegagrus branches, diverged concomitantly at the interface between the Epipaleolithic and early Neolithic periods, and underwent a dramatic expansion starting from ~12-10 ka ago. Conclusions Domestic goat mitogenomes descended from a small number of founding haplotypes that underwent domestication after surviving the last glacial maximum in the Near Eastern refuges. All modern haplotypes A probably descended from a single (or at most a few closely related) female C. aegagrus. Zooarchaelogical data indicate that domestication first occurred in Southeastern Anatolia. Goats accompanying the first Neolithic migration waves into the Mediterranean were already characterized by two ancestral A and C variants. The ancient separation of the C branch (~130 ka ago) suggests a genetically distinct population that could have been involved in a second event of domestication. The novel diagnostic mutational motifs defined here, which distinguish wild and domestic haplogroups, could be used to understand phylogenetic relationships among modern breeds and ancient remains and to evaluate whether selection differentially affected mitochondrial genome variants during the development of economically important breeds.

Keywords

Goat mitochondrial genome; mtDNA haplogroups; domestication; origin of Capra hircus; Capra aegagrus.

External links

About this resource

• Canonical resource URI: http://purl.org/phylo/treebase/phylows/study/TB2:S18595
• Other versions: Nexus NeXML
• Show BibTeX reference

  		@ARTICLE{TreeBASE2Ref25372,
  	 author = {Licia  Colli and Hovirag  Lancioni and Irene  Cardinali and Anna  Olivieri and Marco Rosario  Capodiferro and Marco  Pellecchia and Marcin  Rzepus and Wahid  Zamani and Saeid  Naderi and Francesca  Gandini and Seyed Mohammad Farhad  Vahidi and Saif  Agha and Ettore  Randi and Vincenza  Battaglia and Maria Teresa  Sardina and Baldassare  Portolano and Hamid Reza  Rezaei and Petros  Lymberakis and Frédéric  Boyer and Eric  Coissac and François  Pompanon and Pierre  Taberlet and Paolo  Ajmone Marsan and Alessandro  Achilli},
  	 title = {Whole Mitochondrial Genomes Unveil the Impact of Domestication on Goat Matrilineal Variability},
  	 year = {2015},
  	 keywords = {Goat mitochondrial genome; mtDNA haplogroups; domestication; origin of Capra hircus; Capra aegagrus.},
  	 doi = {},
  	 url = {http://},
  	 pmid = {},
  	 journal = {BMC Genomics},
  	 volume = {},
  	 number = {},
  	 pages = {},
  	 abstract = {Background
  The current extensive use of the domestic goat (Capra hircus) is the result of its medium size and high adaptability as multiple breeds. The extent to which its genetic variability was influenced by early domestication practices is largely unknown. A common standard by which to analyze maternally-inherited variability of livestock species is through complete sequencing of the entire mitogenome (mitochondrial DNA, mtDNA).
  Results
  We present the first extensive survey of goat mitogenomic variability based on 84 complete sequences selected from an initial collection of 758 samples that represent 60 different breeds of C. hircus, as well as its wild sister species, bezoar (Capra aegagrus) from Iran. Our phylogenetic analyses dated the most recent common ancestor of C. hircus to ~460 thousand years (ka) ago and identified five distinctive domestic haplogroups (A, B1, C1a, D1 and G). More than 90% of goats examined were in haplogroup A. These domestic lineages are predominantly nested within C. aegagrus branches, diverged concomitantly at the interface between the Epipaleolithic and early Neolithic periods, and underwent a dramatic expansion starting from ~12-10 ka ago.
  Conclusions
  Domestic goat mitogenomes descended from a small number of founding haplotypes that underwent domestication after surviving the last glacial maximum in the Near Eastern refuges. All modern haplotypes A probably descended from a single (or at most a few closely related) female C. aegagrus. Zooarchaelogical data indicate that domestication first occurred in Southeastern Anatolia. Goats accompanying the first Neolithic migration waves into the Mediterranean were already characterized by two ancestral A and C variants. The ancient separation of the C branch (~130 ka ago) suggests a genetically distinct population that could have been involved in a second event of domestication. The novel diagnostic mutational motifs defined here, which distinguish wild and domestic haplogroups, could be used to understand phylogenetic relationships among modern breeds and ancient remains and to evaluate whether selection differentially affected mitochondrial genome variants during the development of economically important breeds.
  }
  }
  		

• Show RIS reference

  		TY  - JOUR
  ID  - 25372
  AU  - Colli,Licia 
  AU  - Lancioni,Hovirag 
  AU  - Cardinali,Irene 
  AU  - Olivieri,Anna 
  AU  - Capodiferro,Marco Rosario 
  AU  - Pellecchia,Marco 
  AU  - Rzepus,Marcin 
  AU  - Zamani,Wahid 
  AU  - Naderi,Saeid 
  AU  - Gandini,Francesca 
  AU  - Vahidi,Seyed Mohammad Farhad 
  AU  - Agha,Saif 
  AU  - Randi,Ettore 
  AU  - Battaglia,Vincenza 
  AU  - Sardina,Maria Teresa 
  AU  - Portolano,Baldassare 
  AU  - Rezaei,Hamid Reza 
  AU  - Lymberakis,Petros 
  AU  - Boyer,Frédéric 
  AU  - Coissac,Eric 
  AU  - Pompanon,François 
  AU  - Taberlet,Pierre 
  AU  - Ajmone Marsan,Paolo 
  AU  - Achilli,Alessandro 
  T1  - Whole Mitochondrial Genomes Unveil the Impact of Domestication on Goat Matrilineal Variability
  PY  - 2015
  KW  - Goat mitochondrial genome; mtDNA haplogroups; domestication; origin of Capra hircus; Capra aegagrus.
  UR  - http://dx.doi.org/
  N2  - Background
  The current extensive use of the domestic goat (Capra hircus) is the result of its medium size and high adaptability as multiple breeds. The extent to which its genetic variability was influenced by early domestication practices is largely unknown. A common standard by which to analyze maternally-inherited variability of livestock species is through complete sequencing of the entire mitogenome (mitochondrial DNA, mtDNA).
  Results
  We present the first extensive survey of goat mitogenomic variability based on 84 complete sequences selected from an initial collection of 758 samples that represent 60 different breeds of C. hircus, as well as its wild sister species, bezoar (Capra aegagrus) from Iran. Our phylogenetic analyses dated the most recent common ancestor of C. hircus to ~460 thousand years (ka) ago and identified five distinctive domestic haplogroups (A, B1, C1a, D1 and G). More than 90% of goats examined were in haplogroup A. These domestic lineages are predominantly nested within C. aegagrus branches, diverged concomitantly at the interface between the Epipaleolithic and early Neolithic periods, and underwent a dramatic expansion starting from ~12-10 ka ago.
  Conclusions
  Domestic goat mitogenomes descended from a small number of founding haplotypes that underwent domestication after surviving the last glacial maximum in the Near Eastern refuges. All modern haplotypes A probably descended from a single (or at most a few closely related) female C. aegagrus. Zooarchaelogical data indicate that domestication first occurred in Southeastern Anatolia. Goats accompanying the first Neolithic migration waves into the Mediterranean were already characterized by two ancestral A and C variants. The ancient separation of the C branch (~130 ka ago) suggests a genetically distinct population that could have been involved in a second event of domestication. The novel diagnostic mutational motifs defined here, which distinguish wild and domestic haplogroups, could be used to understand phylogenetic relationships among modern breeds and ancient remains and to evaluate whether selection differentially affected mitochondrial genome variants during the development of economically important breeds.
  
  L3  - 
  JF  - BMC Genomics
  VL  - 
  IS  - 
  ER  -