CiteULike

Delicious

Connotea

Citation for Study 21918

Citation title: "The emerging picture of the mitochondrial protein import complexes of Amoebozoa supergroup".

Study name: "The emerging picture of the mitochondrial protein import complexes of Amoebozoa supergroup".

This study is part of submission 21918 (Status: Published).

Citation

Wojtkowska M., Buczek D., Suzuki Y., Shabardina V., Makałowski W., & Kmita H. 2017. The emerging picture of the mitochondrial protein import complexes of Amoebozoa supergroup. BMC Genomics, .

Authors

• Wojtkowska M. (submitter) +48505126815
• Buczek D.
• Suzuki Y.
• Shabardina V.
• Makałowski W.
• Kmita H.

Abstract

Background: The existence of mitochondria-related organelles (MROs) is proposed for eukaryotic organisms. The Amoebozoa includes some organisms that are known to have mitosomes but also organisms that have aerobic mitochondria. However, the mitochondrial protein apparatus of this supergroup remains largely unsampled, except for the mitochondrial outer membrane import complexes studied recently. Therefore, in this study we investigated the mitochondrial inner membrane and intermembrane space complexes, using the available genome and transcriptome sequences. Results: When compared with the canonical cognate complexes described for the yeast Saccharomyces cerevisiae, amoebozoans with aerobic mitochondria, display lower differences in the number of subunits predicted for these complexes than the mitochondrial outer membrane complexes, although the predicted subunits appear to display different levels of diversity in regard to phylogenetic position and isoform numbers. For the putative mitosome-bearing amoebozoans, the number of predicted subunits suggests the complex elimination distinctly more pronounced than in the case of the outer membrane ones. Conclusion: The results concern the problem of mitochondrial and mitosome protein import machinery structural variability and the reduction of their complexity within the currently defined supergroup of Amoebozoa. This results are crucial for better understanding of the Amoebozoa taxa of both biomedical and evolutionary importance.

Keywords

Amoebozoa, mitochondria, mitosomes, protein import, TIM22 complex, TIM23 complex, small Tims, MIA complex, PAM complex, OXA complex

External links

• DOI: 10.1186/s12864-017-4383-1

About this resource

• Canonical resource URI: http://purl.org/phylo/treebase/phylows/study/TB2:S21918
• Other versions: Nexus NeXML
• Show BibTeX reference

  		@ARTICLE{TreeBASE2Ref27882,
  	 author = {MAŁGORZATA  WOJTKOWSKA and Dorota  Buczek and Yutaka  Suzuki and Victoria  Shabardina and Wojciech  Makałowski and Hanna  Kmita},
  	 title = {The emerging picture of the mitochondrial protein import complexes of Amoebozoa supergroup},
  	 year = {2017},
  	 keywords = {Amoebozoa, mitochondria, mitosomes, protein import, TIM22 complex, TIM23 complex, small Tims, MIA complex, PAM complex, OXA complex },
  	 doi = {10.1186/s12864-017-4383-1},
  	 url = {http://},
  	 pmid = {},
  	 journal = {BMC Genomics},
  	 volume = {},
  	 number = {},
  	 pages = {},
  	 abstract = {Background: The existence of mitochondria-related organelles (MROs) is proposed for eukaryotic organisms. The Amoebozoa includes some organisms that are known to have mitosomes but also organisms that have aerobic mitochondria. However, the mitochondrial protein apparatus of this supergroup remains largely unsampled, except for the mitochondrial outer membrane import complexes studied recently. Therefore, in this study we investigated the mitochondrial inner membrane and intermembrane space complexes, using the available genome and transcriptome sequences. 
  Results: When compared with the canonical cognate complexes described for the yeast Saccharomyces cerevisiae, amoebozoans with aerobic mitochondria, display lower differences in the number of subunits predicted for these complexes than the mitochondrial outer membrane complexes, although the predicted subunits appear to display different levels of diversity in regard to phylogenetic position and isoform numbers. For the putative mitosome-bearing amoebozoans, the number of predicted subunits suggests the complex elimination distinctly more pronounced than in the case of the outer membrane ones.
  Conclusion: The results concern the problem of mitochondrial and mitosome protein import machinery structural variability and the reduction of their complexity within the currently defined supergroup of Amoebozoa. This results are crucial for better understanding of the Amoebozoa taxa of both biomedical and evolutionary importance.
  
  }
  }
  		

• Show RIS reference

  		TY  - JOUR
  ID  - 27882
  AU  - WOJTKOWSKA,MAŁGORZATA 
  AU  - Buczek,Dorota 
  AU  - Suzuki,Yutaka 
  AU  - Shabardina,Victoria 
  AU  - Makałowski,Wojciech 
  AU  - Kmita,Hanna 
  T1  - The emerging picture of the mitochondrial protein import complexes of Amoebozoa supergroup
  PY  - 2017
  KW  - Amoebozoa
  KW  - mitochondria
  KW  - mitosomes
  KW  - protein import
  KW  - TIM22 complex
  KW  - TIM23 complex
  KW  - small Tims
  KW  - MIA complex
  KW  - PAM complex
  KW  - OXA complex 
  UR  - http://dx.doi.org/10.1186/s12864-017-4383-1
  N2  - Background: The existence of mitochondria-related organelles (MROs) is proposed for eukaryotic organisms. The Amoebozoa includes some organisms that are known to have mitosomes but also organisms that have aerobic mitochondria. However, the mitochondrial protein apparatus of this supergroup remains largely unsampled, except for the mitochondrial outer membrane import complexes studied recently. Therefore, in this study we investigated the mitochondrial inner membrane and intermembrane space complexes, using the available genome and transcriptome sequences. 
  Results: When compared with the canonical cognate complexes described for the yeast Saccharomyces cerevisiae, amoebozoans with aerobic mitochondria, display lower differences in the number of subunits predicted for these complexes than the mitochondrial outer membrane complexes, although the predicted subunits appear to display different levels of diversity in regard to phylogenetic position and isoform numbers. For the putative mitosome-bearing amoebozoans, the number of predicted subunits suggests the complex elimination distinctly more pronounced than in the case of the outer membrane ones.
  Conclusion: The results concern the problem of mitochondrial and mitosome protein import machinery structural variability and the reduction of their complexity within the currently defined supergroup of Amoebozoa. This results are crucial for better understanding of the Amoebozoa taxa of both biomedical and evolutionary importance.
  
  
  L3  - 10.1186/s12864-017-4383-1
  JF  - BMC Genomics
  VL  - 
  IS  - 
  ER  -