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Citation for Study 796

Citation title: "Evolved RNA secondary structure and the rooting of the universal tree of life.".

This study was previously identified under the legacy study ID S653 (Status: Published).

Citation

Caetano-anoll?s G. 2002. Evolved RNA secondary structure and the rooting of the universal tree of life. Journal of Molecular Evolution, 54(3): 333-345.

Authors

• Caetano-anoll?s G.

Abstract

The origin and diversification of RNA secondary structure were traced using cladistic methods. Structural components were coded as polarized and ordered multi-state characters, following a model of character state transformation outlined by considerations in statistical mechanics. Several classes of functional RNA were analyzed, including ribosomal RNA (rRNA). Considerable phylogenetic signal was present in their secondary structure. The intrinsically rooted phylogenies reconstructed from evolved RNA structure depicted those derived from nucleic acid sequence at all taxonomical levels, and grouped organisms in concordance with traditional classification, especially in the archaeal and eukaryal domains. Natural selection appears therefore to operate early in the information flow that originates in sequence and ends in an adapted phenotype. When examining the hierarchical classification of the living world, phylogenetic analysis of secondary structure of the small and large rRNA subunits reconstructed a universal tree of life that branched in three monophyletic groups corresponding to Eucarya, Archaea and Bacteria, and was rooted in the eukaryotic branch. Ribosomal characters involved in the translational cycle could be easily traced and showed that transfer RNA (tRNA) binding domains in the large rRNA subunit evolved concurrently with the rest of the rRNA molecule. Results suggest it is equally parsimonious to consider that ancestral unicellular eukaryotes or prokaryotes gave rise to all extant life forms and provide a rare insight into the early evolution of nucleic acid and protein biosynthesis.

Keywords

Cladistic analysis; Molecular evolution; Ribosomal RNA; Secondary structure; Universal tree

External links

• DOI: 10.1007/s00239-001-0048-3
• PMID: 11847559
• Other URL: http://www.springerlink.com/content/h9wq8ukvv7crgqgp/

About this resource

• Canonical resource URI: http://purl.org/phylo/treebase/phylows/study/TB2:S796
• Other versions: Nexus NeXML
• Show BibTeX reference

  		@ARTICLE{TreeBASE2Ref14896,
  	 author = {Gustavo  Caetano-Anoll?s},
  	 title = {Evolved RNA secondary structure and the rooting of the universal tree of life.},
  	 year = {2002},
  	 keywords = {Cladistic analysis; Molecular evolution; Ribosomal RNA; Secondary structure; Universal tree},
  	 doi = {10.1007/s00239-001-0048-3},
  	 url = {http://www.springerlink.com/content/h9wq8ukvv7crgqgp/},
  	 pmid = {11847559 },
  	 journal = {Journal of Molecular Evolution},
  	 volume = {54},
  	 number = {3},
  	 pages = {333--345},
  	 abstract = {The origin and diversification of RNA secondary structure were traced using cladistic methods. Structural components were coded as polarized and ordered multi-state characters, following a model of character state transformation outlined by considerations in statistical mechanics. Several classes of functional RNA were analyzed, including ribosomal RNA (rRNA). Considerable phylogenetic signal was present in their secondary structure. The intrinsically rooted phylogenies reconstructed from evolved RNA structure depicted those derived from nucleic acid sequence at all taxonomical levels, and grouped organisms in concordance with traditional classification, especially in the archaeal and eukaryal domains. Natural selection appears therefore to operate early in the information flow that originates in sequence and ends in an adapted phenotype. When examining the hierarchical classification of the living world, phylogenetic analysis of secondary structure of the small and large rRNA subunits reconstructed a universal tree of life that branched in three monophyletic groups corresponding to Eucarya, Archaea and Bacteria, and was rooted in the eukaryotic branch. Ribosomal characters involved in the translational cycle could be easily traced and showed that transfer RNA (tRNA) binding domains in the large rRNA subunit evolved concurrently with the rest of the rRNA molecule. Results suggest it is equally parsimonious to consider that ancestral unicellular eukaryotes or prokaryotes gave rise to all extant life forms and provide a rare insight into the early evolution of nucleic acid and protein biosynthesis.}
  }
  		

• Show RIS reference

  		TY  - JOUR
  ID  - 14896
  AU  - Caetano-Anoll?s,Gustavo 
  T1  - Evolved RNA secondary structure and the rooting of the universal tree of life.
  PY  - 2002
  KW  - Cladistic analysis; Molecular evolution; Ribosomal RNA; Secondary structure; Universal tree
  UR  - http://www.springerlink.com/content/h9wq8ukvv7crgqgp/
  N2  - The origin and diversification of RNA secondary structure were traced using cladistic methods. Structural components were coded as polarized and ordered multi-state characters, following a model of character state transformation outlined by considerations in statistical mechanics. Several classes of functional RNA were analyzed, including ribosomal RNA (rRNA). Considerable phylogenetic signal was present in their secondary structure. The intrinsically rooted phylogenies reconstructed from evolved RNA structure depicted those derived from nucleic acid sequence at all taxonomical levels, and grouped organisms in concordance with traditional classification, especially in the archaeal and eukaryal domains. Natural selection appears therefore to operate early in the information flow that originates in sequence and ends in an adapted phenotype. When examining the hierarchical classification of the living world, phylogenetic analysis of secondary structure of the small and large rRNA subunits reconstructed a universal tree of life that branched in three monophyletic groups corresponding to Eucarya, Archaea and Bacteria, and was rooted in the eukaryotic branch. Ribosomal characters involved in the translational cycle could be easily traced and showed that transfer RNA (tRNA) binding domains in the large rRNA subunit evolved concurrently with the rest of the rRNA molecule. Results suggest it is equally parsimonious to consider that ancestral unicellular eukaryotes or prokaryotes gave rise to all extant life forms and provide a rare insight into the early evolution of nucleic acid and protein biosynthesis.
  L3  - 10.1007/s00239-001-0048-3
  JF  - Journal of Molecular Evolution
  VL  - 54
  IS  - 3
  SP  - 333
  EP  - 345
  ER  -