@ARTICLE{TreeBASE2Ref26078,
author = {Alex Clop and Abdoallah Sharaf and Anna Castell? and Sebastian E. Ramos-Onsins and Susanna Cirera and Anna Mercad? and Sophia Derdak and Sergi Beltran and Abe Huisman and Merete Fredholm and Pieter van As and Armand S?nchez},
title = {Identification of protein-damaging mutations in 10 swine taste receptors and 191 appetite-reward genes.},
year = {2016},
keywords = {},
doi = {},
url = {http://},
pmid = {},
journal = {BMC Genomics},
volume = {},
number = {},
pages = {},
abstract = {Taste receptors (TASRs) are essential for the body?s recognition of chemical compounds. In the tongue, TASRs sense the sweet and umami and the toxin-related bitter taste thus promoting a particular eating behaviour. Moreover, their relevance in other organs is now becoming evident. In the intestine, they regulate nutrient absorption and gut motility. Upon ligand binding, TASRs activate the appetite-reward circuitry to signal the nervous system and keep body homeostasis. With the aim to identify genetic variation in the swine TASRs and in the genes from the appetite and the reward pathways, we have sequenced the exons of 201 TASRs and appetite-reward genes from 304 pigs belonging to ten breeds and to two phenotypically extreme groups from a F2 resource with data on growth and fat deposition. }
}
Taxa for tree 97141 of Study 19540
Citation title:
"Identification of protein-damaging mutations in 10 swine taste receptors and 191 appetite-reward genes.".
Study name:
"Identification of protein-damaging mutations in 10 swine taste receptors and 191 appetite-reward genes.".
This study is part of submission 19540
(Status: Published).
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