@ARTICLE{TreeBASE2Ref24680, author = {E. Sally Chang and Moran Neuhof and Nimrod Rubinstein and Arik Diamant and Herv? Philippe and Dorothee Huchon and Paulyn Cartwright}, title = {Genomic insights into the evolutionary origin of Myxozoa within Cnidaria}, year = {2015}, keywords = {Myxozoa, Cnidaria, parasite, genome}, doi = {10.1073/pnas.1511468112}, url = {http://www.pnas.org/cgi/doi/10.1073/pnas.1511468112}, pmid = {}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, volume = {}, number = {}, pages = {}, abstract = {Myxozoans are a diverse group of microscopic parasites that infect invertebrate and vertebrate hosts. The assertion that myxozoans are highly reduced cnidarians is supported by the presence of polar capsules, which resemble cnidarian stinging structures called nematocysts. Our study characterizes the genomes and transcriptomes of two distantly related myxozoan species, Kudoa iwatai and Myxobolus cerebralis, and another cnidarian parasite Polypodium hydriforme. A phylogenomic analysis, using the most extensive sampling of myxozoans to date, confirms the phylogenetic position of myxozoans within Cnidaria, with Polypodium as the sister taxon to Myxozoa. Analyses of myxozoan genomes indicate that the transition to the highly reduced body plan was accompanied by massive reduction in genome size, including depletion of genes considered hallmarks of animal multicellularity. } }

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