@ARTICLE{TreeBASE2Ref26191,
author = {Charlotte Avanzi and Jorge del-Pozo and Andrej Benjak and Karen Stevenson and Victor R. Simpson and Philippe Busso and Joyce McLuckie and Chlo? Loiseau and Colin Lawton and Janne Schoening and Darren J. Shaw and J?r?mie Piton and Lucio Vera-Cabrera and Jes? S. Velarde-Felix and Fergal McDermott and Stephen V. Gordon and Stewart T. Cole and Anna L. Meredith},
title = {Red squirrels in the British Isles are infected with leprosy bacilli},
year = {2016},
keywords = {},
doi = {},
url = {http://},
pmid = {},
journal = {Science},
volume = {},
number = {},
pages = {},
abstract = {Leprosy, caused by infection with Mycobacterium leprae or the recently discovered Mycobacterium lepromatosis, was once endemic in humans in the British Isles. UK red squirrels (Sciurus vulgaris) have increasingly been observed with leprosy-like lesions on the head and limbs. Using genomics, histopathology and serology we found M. lepromatosis in squirrels from England, Ireland and Scotland, and M. leprae in squirrels from Brownsea Island, England. Infection was detected in overtly diseased and seemingly healthy animals. Phylogenetic comparisons of British and Irish M. lepromatosis with two Mexican strains from humans showed they diverged from a common ancestor around 27,000 years ago whereas the M. leprae strain is closest to one that circulated in Medieval England. Red squirrels are thus a reservoir for leprosy in the British Isles.}
}
Matrices for Study 19692
Citation title:
"Red squirrels in the British Isles are infected with leprosy bacilli".
Study name:
"Red squirrels in the British Isles are infected with leprosy bacilli".
This study is part of submission 19692
(Status: Published).
Matrices
| ID |
Matrix Title |
Description |
Data type |
NTAX |
NCHAR |
Taxa |
|
|
|
|
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M37588
|
Fig. 3A M. lepromatosis SNP alignments for BEAST |
M.lepromatosis SNP alignments for BEAST |
Nucleic Acid |
9 |
432 |
View Taxa
|
|
|
|
|
|
M37586
|
Fig. S4A Mycobacterium leprae SNP alignments for MP |
M.leprae SNP alignments for MP |
Nucleic Acid |
28 |
865 |
View Taxa
|
|
|
|
|
|
M37590
|
Fig. 3B Mycobacterium leprae SNP alignments for BEAST |
M.leprae SNP alignments for BEAST |
Nucleic Acid |
23 |
498 |
View Taxa
|
|
|
|
|
|
M37589
|
Fig. S4B M. lepromatosis SNP alignments for MP |
M.lepromatosis SNP alignments for MP |
Nucleic Acid |
10 |
436 |
View Taxa
|
|
|
|
|
|
M37587
|
Fig. S5 Mycobacterium leprae and M. lepromatosis SNP alignments for NJ |
M.leprae and M.lepromatosis SNP alignments for NJ |
Nucleic Acid |
33 |
311324 |
View Taxa
|
|
|
|
|
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