TreeBASE Search-Citation for study 19692

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Citation for Study 19692

Citation title: "Red squirrels in the British Isles are infected with leprosy bacilli".

Study name: "Red squirrels in the British Isles are infected with leprosy bacilli".

This study is part of submission 19692 (Status: Published).

Citation

Avanzi C., Del-pozo J., Benjak A., Stevenson K., Simpson V.R., Busso P., Mcluckie J., Loiseau C., Lawton C., Schoening J., Shaw D.J., Piton J., Vera-cabrera L., Velarde-felix J.S., Mcdermott F., Gordon S.V., Cole S.T., & Meredith A.L. 2016. Red squirrels in the British Isles are infected with leprosy bacilli. Science, .

Authors

Avanzi C.
Del-pozo J.
Benjak A.
Stevenson K.
Simpson V.R.
Busso P.
Mcluckie J.
Loiseau C.
Lawton C.
Schoening J.
Shaw D.J.
Piton J.
Vera-cabrera L.
Velarde-felix J.S.
Mcdermott F.
Gordon S.V.
Cole S.T.
Meredith A.L.

Abstract

Leprosy, caused by infection with Mycobacterium leprae or the recently discovered Mycobacterium lepromatosis, was once endemic in humans in the British Isles. UK red squirrels (Sciurus vulgaris) have increasingly been observed with leprosy-like lesions on the head and limbs. Using genomics, histopathology and serology we found M. lepromatosis in squirrels from England, Ireland and Scotland, and M. leprae in squirrels from Brownsea Island, England. Infection was detected in overtly diseased and seemingly healthy animals. Phylogenetic comparisons of British and Irish M. lepromatosis with two Mexican strains from humans showed they diverged from a common ancestor around 27,000 years ago whereas the M. leprae strain is closest to one that circulated in Medieval England. Red squirrels are thus a reservoir for leprosy in the British Isles.

External links

About this resource

Canonical resource URI: http://purl.org/phylo/treebase/phylows/study/TB2:S19692
Other versions: Nexus NeXML

Show BibTeX reference

		@ARTICLE{TreeBASE2Ref26191,
	 author = {Charlotte  Avanzi and Jorge  del-Pozo and Andrej  Benjak and Karen  Stevenson and Victor R. Simpson and Philippe  Busso and Joyce  McLuckie and Chlo?  Loiseau and Colin  Lawton and Janne  Schoening and Darren J. Shaw and J?r?mie  Piton and Lucio  Vera-Cabrera and Jes? S. Velarde-Felix and Fergal  McDermott and Stephen V. Gordon and Stewart T. Cole and Anna L. Meredith},
	 title = {Red squirrels in the British Isles are infected with leprosy bacilli},
	 year = {2016},
	 keywords = {},
	 doi = {},
	 url = {http://},
	 pmid = {},
	 journal = {Science},
	 volume = {},
	 number = {},
	 pages = {},
	 abstract = {Leprosy, caused by infection with Mycobacterium leprae or the recently discovered Mycobacterium lepromatosis, was once endemic in humans in the British Isles. UK red squirrels (Sciurus vulgaris) have increasingly been observed with leprosy-like lesions on the head and limbs.  Using genomics, histopathology and serology we found M. lepromatosis in squirrels from England, Ireland and Scotland, and M. leprae in squirrels from Brownsea Island, England.  Infection was detected in overtly diseased and seemingly healthy animals.  Phylogenetic comparisons of British and Irish M. lepromatosis with two Mexican strains from humans showed they diverged from a common ancestor around 27,000 years ago whereas the M. leprae strain is closest to one that circulated in Medieval England.  Red squirrels are thus a reservoir for leprosy in the British Isles.}
}

Show RIS reference

		TY  - JOUR
ID  - 26191
AU  - Avanzi,Charlotte 
AU  - del-Pozo,Jorge 
AU  - Benjak,Andrej 
AU  - Stevenson,Karen 
AU  - Simpson,Victor R.
AU  - Busso,Philippe 
AU  - McLuckie,Joyce 
AU  - Loiseau,Chlo? 
AU  - Lawton,Colin 
AU  - Schoening,Janne 
AU  - Shaw,Darren J.
AU  - Piton,J?r?mie 
AU  - Vera-Cabrera,Lucio 
AU  - Velarde-Felix,Jes? S.
AU  - McDermott,Fergal 
AU  - Gordon,Stephen V.
AU  - Cole,Stewart T.
AU  - Meredith,Anna L.
T1  - Red squirrels in the British Isles are infected with leprosy bacilli
PY  - 2016
KW  - 
UR  - http://dx.doi.org/
N2  - Leprosy, caused by infection with Mycobacterium leprae or the recently discovered Mycobacterium lepromatosis, was once endemic in humans in the British Isles. UK red squirrels (Sciurus vulgaris) have increasingly been observed with leprosy-like lesions on the head and limbs.  Using genomics, histopathology and serology we found M. lepromatosis in squirrels from England, Ireland and Scotland, and M. leprae in squirrels from Brownsea Island, England.  Infection was detected in overtly diseased and seemingly healthy animals.  Phylogenetic comparisons of British and Irish M. lepromatosis with two Mexican strains from humans showed they diverged from a common ancestor around 27,000 years ago whereas the M. leprae strain is closest to one that circulated in Medieval England.  Red squirrels are thus a reservoir for leprosy in the British Isles.
L3  - 
JF  - Science
VL  - 
IS  - 
ER  -