TreeBASE Search-Citation for study 22798

Delicious

Citation for Study 22798

Citation title: "Genome-wide identification and expression of the entire 90 glutathione S-transferase (GST) subfamily genes in four rotifer Brachionus species and transcriptional modulation in response to endocrine disrupting chemicals".

Study name: "Genome-wide identification and expression of the entire 90 glutathione S-transferase (GST) subfamily genes in four rotifer Brachionus species and transcriptional modulation in response to endocrine disrupting chemicals".

This study is part of submission 22798 (Status: Published).

Citation

Park J., Lee J., Kim H., Kim D., Lee M., Han J., Hagiwara A., Hwang U., & Park H. 2018. Genome-wide identification and expression of the entire 90 glutathione S-transferase (GST) subfamily genes in four rotifer Brachionus species and transcriptional modulation in response to endocrine disrupting chemicals. BMC genomics, .

Authors

Park J.
Lee J.
Kim H.
Kim D. (submitter) +82-10-8929-9576
Lee M.
Han J.
Hagiwara A.
Hwang U.
Park H.

Abstract

Genome-wide identification of glutathione S-transferase (GST), a major phase II detoxification enzyme, was investigated in four different aquatic model rotifer species Brachionus koreanus, B. plicatilis, B. rotundiformis, and B. calyciflorus. GSTs are ubiquitous antioxidant enzymes that play versatile function including cellular detoxification, stress alleviation, and production of the radical conjugates. Among the four rotifers, B. rotundiformis were found with the least number of GST genes (total 19 GST genes), whereas the other three species shared 23 to 24 GST genes. Among the identified GST genes, the expansion of GST sigma classes mainly occurs through tandem duplication, resulting in tandem-arrayed gene clusters on the chromosomes. Overall, the number of genes discovered in this study was highest in the sigma class, zeta, alpha, and omega in the descending order. With integration of phylogenetic analysis and xenobiotic-mediated GST mRNA expression patterns along with previous enzymatic activities, the functional divergence among species-specific GST genes was clearly observed. This study covers full identification of GST superfamily and their critical role in marine environmental ecotoxicology.

Keywords

Glutathione S-transferase, genome-wide identification, detoxification, rotifer, tandem duplication

External links

About this resource

Canonical resource URI: http://purl.org/phylo/treebase/phylows/study/TB2:S22798
Other versions: Nexus NeXML

Show BibTeX reference

		@ARTICLE{TreeBASE2Ref28500,
	 author = {Jun Chul  Park and Jae-Seong  Lee and Hui-Su  Kim and Duck-Hyun  Kim and Min-Chul  Lee and Jeonghoon  Han and Atsushi  Hagiwara and un-Ki  Hwang and Heum Gi  Park},
	 title = {Genome-wide identification and expression of the entire 90 glutathione S-transferase (GST) subfamily genes in four rotifer Brachionus species and transcriptional modulation in response to endocrine disrupting chemicals},
	 year = {2018},
	 keywords = {Glutathione S-transferase, genome-wide identification, detoxification, rotifer, tandem duplication},
	 doi = {},
	 url = {http://},
	 pmid = {},
	 journal = {BMC genomics},
	 volume = {},
	 number = {},
	 pages = {},
	 abstract = {Genome-wide identification of glutathione S-transferase (GST), a major phase II detoxification enzyme, was investigated in four different aquatic model rotifer species Brachionus koreanus, B. plicatilis, B. rotundiformis, and B. calyciflorus. GSTs are ubiquitous antioxidant enzymes that play versatile function including cellular detoxification, stress alleviation, and production of the radical conjugates. Among the four rotifers, B. rotundiformis were found with the least number of GST genes (total 19 GST genes), whereas the other three species shared 23 to 24 GST genes. Among the identified GST genes, the expansion of GST sigma classes mainly occurs through tandem duplication, resulting in tandem-arrayed gene clusters on the chromosomes. Overall, the number of genes discovered in this study was highest in the sigma class, zeta, alpha, and omega in the descending order. With integration of phylogenetic analysis and xenobiotic-mediated GST mRNA expression patterns along with previous enzymatic activities, the functional divergence among species-specific GST genes was clearly observed. This study covers full identification of GST superfamily and their critical role in marine environmental ecotoxicology.}
}

Show RIS reference

TY - JOUR
ID - 28500
AU - Park,Jun Chul
AU - Lee,Jae-Seong
AU - Kim,Hui-Su
AU - Kim,Duck-Hyun
AU - Lee,Min-Chul
AU - Han,Jeonghoon
AU - Hagiwara,Atsushi
AU - Hwang,un-Ki
AU - Park,Heum Gi
T1 - Genome-wide identification and expression of the entire 90 glutathione S-transferase (GST) subfamily genes in four rotifer Brachionus species and transcriptional modulation in response to endocrine disrupting chemicals
PY - 2018
KW - Glutathione S-transferase
KW - genome-wide identification
KW - detoxification
KW - rotifer
KW - tandem duplication
UR - http://dx.doi.org/
N2 - Genome-wide identification of glutathione S-transferase (GST), a major phase II detoxification enzyme, was investigated in four different aquatic model rotifer species Brachionus koreanus, B. plicatilis, B. rotundiformis, and B. calyciflorus. GSTs are ubiquitous antioxidant enzymes that play versatile function including cellular detoxification, stress alleviation, and production of the radical conjugates. Among the four rotifers, B. rotundiformis were found with the least number of GST genes (total 19 GST genes), whereas the other three species shared 23 to 24 GST genes. Among the identified GST genes, the expansion of GST sigma classes mainly occurs through tandem duplication, resulting in tandem-arrayed gene clusters on the chromosomes. Overall, the number of genes discovered in this study was highest in the sigma class, zeta, alpha, and omega in the descending order. With integration of phylogenetic analysis and xenobiotic-mediated GST mRNA expression patterns along with previous enzymatic activities, the functional divergence among species-specific GST genes was clearly observed. This study covers full identification of GST superfamily and their critical role in marine environmental ecotoxicology.
L3 -
JF - BMC genomics
VL -
IS -
ER -