@ARTICLE{TreeBASE2Ref28231,
author = {Hassiba BELAHBIB and Emmanuelle Renard and Sebastien Santini and Cyril Jourda and Jean Michel Clavery and Carole Borchiellini and Andre Le Bivic},
title = {New Genomic Data and Analyses Challenge the Traditional Vision of Epithelium Evolution in Sponges and Ctenophores.},
year = {2018},
keywords = {Metazoans, polarity complexes, E-cadherin complex},
doi = {},
url = {http://},
pmid = {},
journal = {BMC Genomics},
volume = {},
number = {},
pages = {},
abstract = {The emergence of epithelia was the foundation of metazoan expansion. To investigate the early evolution of animal epithelia, we characterized epithelial markers such as the E-cadherin complex and the polarity complexes in all classes (Calcarea, Demospongiae, Hexactinellida, Homoscleromorpha) of sponges (phylum Porifera), in Placozoa and in Ctenophora. We found that Placozoa and most sponges possess orthologs of all essential genes encoding proteins found in bilaterian epithelial cells, as well as their conserved interaction domains. In stark contrast, we found that ctenophores lack several major polarity complex components such as the Crumbs complex and Scribble. Furthermore, the E-cadherin ctenophore ortholog exhibits a divergent cytoplasmic domain making it unlikely to be able to interact with its canonical cytoplasmic partners. These unexpected findings are interpreted in the context of the highly debated evolutionary position of Porifera and Ctenophora to challenge the current evolutionary paradigm on the emergence of epithelia.}
}
Matrices for Study 22408

Citation title:
"New Genomic Data and Analyses Challenge the Traditional Vision of Epithelium Evolution in Sponges and Ctenophores.".

Study name:
"New Genomic Data and Analyses Challenge the Traditional Vision of Epithelium Evolution in Sponges and Ctenophores.".

This study is part of submission 22408
(Status: Published).
Matrices
| ID |
Matrix Title |
Description |
Data type |
NTAX |
NCHAR |
Taxa |
|
|
|
|
|
M45622
|
Character Matrix figure 4 tree |
Phylogenetic relationships between GUK proteins |
Amino Acid |
47 |
271 |
View Taxa
|
|
|
|
|
|
M45606
|
Character Matrix figure S1C |
Analyses of alpha-catenins and vinculins sequences |
Amino Acid |
31 |
229 |
View Taxa
|
|
|
|
|
|
M45607
|
Character Matrix figure S2-CR1 |
Structure of Par3 proteins in metazoans |
Amino Acid |
9 |
107 |
View Taxa
|
|
|
|
|
|
M45572
|
Character Matrix figure 1C tree |
Alignment of the cytoplasmic cadherin beta-catenin binding domain (CBD). |
Amino Acid |
17 |
70 |
View Taxa
|
|
|
|
|
|
M45613
|
Character Matrix figure S1B |
Comparison of beta-catenin sequences |
Amino Acid |
19 |
957 |
View Taxa
|
|
|
|
|
|
M45609
|
Character Matrix figure S2-PDZ1 |
Structure of Par3 proteins in metazoans |
Amino Acid |
9 |
99 |
View Taxa
|
|
|
|
|
|
M45623
|
Character Matrix figure 3 tree |
Phylogenetic relationships between members of the Protein Kinase C (PKC) family |
Amino Acid |
60 |
1083 |
View Taxa
|
|
|
|
|
|
M45610
|
Character Matrix figure S2-PDZ2 |
Structure of Par3 proteins in metazoans |
Amino Acid |
9 |
102 |
View Taxa
|
|
|
|
|
|
M45621
|
Character Matrix figure 5 tree |
Domain composition of Crumbs proteins |
Amino Acid |
47 |
71 |
View Taxa
|
|
|
|
|
|
M45575
|
Character Matrix figure S1A tree |
Comparison of p120 sequences |
Amino Acid |
17 |
250 |
View Taxa
|
|
|
|
|
|
M45574
|
Character Matrix figure 2 tree |
Structure of Par3 proteins in metazoans |
Amino Acid |
15 |
271 |
View Taxa
|
|
|
|
|
|
M45624
|
Character Matrix figure 6 tree |
Phylogenetic tree of MAGUK proteins |
Amino Acid |
57 |
393 |
View Taxa
|
|
|
|
|
|
M45573
|
Character Matrix figure 1B tree |
Alignment of the cytoplasmic cadherin p120 binding domain (Juxtamembrane domain, JMD) |
Amino Acid |
17 |
83 |
View Taxa
|
|
|
|
|
|
M45611
|
Character Matrix figure S2-PDZ3 |
Structure of Par3 proteins in metazoans |
Amino Acid |
9 |
122 |
View Taxa
|
|
|
|
|
|
M45608
|
Character Matrix figure S2-CR3 |
Structure of Par3 proteins in metazoans |
Amino Acid |
9 |
35 |
View Taxa
|
|
|
|
|